Dietary change without caloric restriction maintains a youthful profile in ageing yeast

por Horkai, Dorottya, Hadj-Moussa, Hanane, Whale, Alex J., Houseley, Jonathan
Publicado 2023

Stimulation of adaptive gene amplification by origin firing under replication fork constraint

por Whale, Alex J, King, Michelle, Hull, Ryan M, Krueger, Felix, Houseley, Jonathan
Publicado 2022

Senescence in yeast is associated with amplified linear fragments of chromosome XII rather than ribosomal DNA circle accumulation

por Zylstra, Andre, Hadj-Moussa, Hanane, Horkai, Dorottya, Whale, Alex J., Piguet, Baptiste, Houseley, Jonathan
Publicado 2023

Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress

por Hadjicharalambous, Andreas, Whale, Alex J., Can, Geylani, Skehel, J. Mark, Houseley, Jonathan M., Zegerman, Philip
Publicado 2023

Abo1, a conserved bromodomain AAA‐ATPase, maintains global nucleosome occupancy and organisation

por Gal, Csenge, Murton, Heather E, Subramanian, Lakxmi, Whale, Alex J, Moore, Karen M, Paszkiewicz, Konrad, Codlin, Sandra, Bähler, Jürg, Creamer, Kevin M, Partridge, Janet F, Allshire, Robin C, Kent, Nicholas A, Whitehall, Simon K
Publicado 2015

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

por Nunes, Carolina, Depestel, Lisa, Mus, Liselot, Keller, Kaylee M., Delhaye, Louis, Louwagie, Amber, Rishfi, Muhammad, Whale, Alex, Kara, Neesha, Andrews, Simon R., Dela Cruz, Filemon, You, Daoqi, Siddiquee, Armaan, Cologna, Camila Takeno, De Craemer, Sam, Dolman, Emmy, Bartenhagen, Christoph, De Vloed, Fanny, Sanders, Ellen, Eggermont, Aline, Bekaert, Sarah-Lee, Van Loocke, Wouter, Bek, Jan Willem, Dewyn, Givani, Loontiens, Siebe, Van Isterdael, Gert, Decaesteker, Bieke, Tilleman, Laurentijn, Van Nieuwerburgh, Filip, Vermeirssen, Vanessa, Van Neste, Christophe, Ghesquiere, Bart, Goossens, Steven, Eyckerman, Sven, De Preter, Katleen, Fischer, Matthias, Houseley, Jon, Molenaar, Jan, De Wilde, Bram, Roberts, Stephen S., Durinck, Kaat, Speleman, Frank
Publicado 2022