Whole Genome Methylation Analysis of Nondysplastic Barrett Esophagus that Progresses to Invasive Cancer

por Dilworth, Mark P., Nieto, Tom, Stockton, Jo D., Whalley, Celina M., Tee, Louise, James, Jonathan D., Noble, Fergus, Underwood, Tim J., Hallissey, Michael T., Hejmadi, Rahul, Trudgill, Nigel, Tucker, Olga, Beggs, Andrew D.
Publicado 2019

Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting

por Ronson, George E., Starowicz, Katarzyna, Anthony, Elizabeth J., Piberger, Ann Liza, Clarke, Lucy C., Garvin, Alexander J., Beggs, Andrew D., Whalley, Celina M., Edmonds, Matthew J., Beesley, James F. J., Morris, Joanna R.
Publicado 2023

MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids

por Pickles, Oliver J., Wanigasooriya, Kasun, Ptasinska, Anetta, Patel, Akshay J., Robbins, Helen L., Bryer, Claire, Whalley, Celina M., Tee, Louise, Lal, Neeraj, Pinna, Claudia M.A., Elzefzafy, Nahla, Taniere, Philippe, Beggs, Andrew D., Middleton, Gary M.
Publicado 2023

Ultrarapid detection of SARS-CoV-2 RNA using a reverse transcription–free exponential amplification reaction, RTF-EXPAR

por Carter, Jake G., Orueta Iturbe, Lorea, Duprey, Jean-Louis H. A., Carter, Ian R., Southern, Craig D., Rana, Marium, Whalley, Celina M., Bosworth, Andrew, Beggs, Andrew D., Hicks, Matthew R., Tucker, James H. R., Dafforn, Timothy R.
Publicado 2021

Patient Derived Organoids Confirm That PI3K/AKT Signalling Is an Escape Pathway for Radioresistance and a Target for Therapy in Rectal Cancer

por Wanigasooriya, Kasun, Barros-Silva, Joao D., Tee, Louise, El-asrag, Mohammed E., Stodolna, Agata, Pickles, Oliver J., Stockton, Joanne, Bryer, Claire, Hoare, Rachel, Whalley, Celina M., Tyler, Robert, Sillo, Toritseju, Yau, Christopher, Ismail, Tariq, Beggs, Andrew D.
Publicado 2022

Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes

por Goel, Anshita, Ward, Douglas G., Noyvert, Boris, Yu, Minghao, Gordon, Naheema S., Abbotts, Ben, Colbourne, John K., Kissane, Stephen, James, Nicholas D., Zeegers, Maurice P., Cheng, Kar Keung, Cazier, Jean-Baptiste, Whalley, Celina M., Beggs, Andrew D., Palles, Claire, Arnold, Roland, Bryan, Richard T.
Publicado 2022

Targeted deep sequencing of urothelial bladder cancers and associated urinary DNA: a 23‐gene panel with utility for non‐invasive diagnosis and risk stratification

por Ward, Douglas G., Gordon, Naheema S., Boucher, Rebecca H., Pirrie, Sarah J., Baxter, Laura, Ott, Sascha, Silcock, Lee, Whalley, Celina M., Stockton, Joanne D., Beggs, Andrew D., Griffiths, Mike, Abbotts, Ben, Ijakipour, Hanieh, Latheef, Fathimath N., Robinson, Robert A., White, Andrew J., James, Nicholas D., Zeegers, Maurice P., Cheng, K. K., Bryan, Richard T.
Publicado 2019

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

por Sirinukunwattana, Korsuk, Domingo, Enric, Richman, Susan D, Redmond, Keara L, Blake, Andrew, Verrill, Clare, Leedham, Simon J, Chatzipli, Aikaterini, Hardy, Claire, Whalley, Celina M, Wu, Chieh-hsi, Beggs, Andrew D, McDermott, Ultan, Dunne, Philip D, Meade, Angela, Walker, Steven M, Murray, Graeme I, Samuel, Leslie, Seymour, Matthew, Tomlinson, Ian, Quirke, Phil, Maughan, Timothy, Rittscher, Jens, Koelzer, Viktor H
Publicado 2021