Combining modelling and experimental approaches to explain how calcium signatures are decoded by calmodulin‐binding transcription activators (CAMTAs) to produce specific gene expre...

por Liu, Junli, Whalley, Helen J., Knight, Marc R.
Publicado 2015

Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation

por Whalley, Helen J., Porter, Andrew P., Diamantopoulou, Zoi, White, Gavin R. M., Castañeda-Saucedo, Eduardo, Malliri, Angeliki
Publicado 2015

The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels

por Porter, Andrew P., Reed, Hannah, White, Gavin R. M., Ogg, Erinn-Lee, Whalley, Helen J., Malliri, Angeliki
Publicado 2021

Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1

por Amalina, Ilma, Bennett, Ailsa, Whalley, Helen, Perera, David, McGrail, Joanne C., Tighe, Anthony, Procter, David J., Taylor, Stephen S.
Publicado 2021

β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity

por Mack, Natalie A., Porter, Andrew P., Whalley, Helen J., Schwarz, Juliane P., Jones, Richard C., Syed, Azharuddin Sajid, Bjartell, Anders, Anderson, Kurt I., Malliri, Angeliki
Publicado 2012

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

por Simões-Sousa, Susana, Littler, Samantha, Thompson, Sarah L., Minshall, Paul, Whalley, Helen, Bakker, Bjorn, Belkot, Klaudyna, Moralli, Daniela, Bronder, Daniel, Tighe, Anthony, Spierings, Diana C.J., Bah, Nourdine, Graham, Joshua, Nelson, Louisa, Green, Catherine M., Foijer, Floris, Townsend, Paul A., Taylor, Stephen S.
Publicado 2018