Incoherent dose-escalation in phase I trials using the escalation with overdose control approach

por Wheeler, Graham M.
Publicado 2016

AplusB: A Web Application for Investigating A + B Designs for Phase I Cancer Clinical Trials

por Wheeler, Graham M., Sweeting, Michael J., Mander, Adrian P.
Publicado 2016

Toxicity‐dependent feasibility bounds for the escalation with overdose control approach in phase I cancer trials

por Wheeler, Graham M., Sweeting, Michael J., Mander, Adrian P.
Publicado 2017

Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

por Burnett, Thomas, Mozgunov, Pavel, Pallmann, Philip, Villar, Sofia S., Wheeler, Graham M., Jaki, Thomas
Publicado 2020

Modelling semi‐attributable toxicity in dual‐agent phase I trials with non‐concurrent drug administration

por Wheeler, Graham M., Sweeting, Michael J., Mander, Adrian P., Lee, Shing M., Cheung, Ying Kuen K.
Publicado 2016

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

por Pallmann, Philip, Wan, Fang, Mander, Adrian P, Wheeler, Graham M, Yap, Christina, Clive, Sally, Hampson, Lisa V, Jaki, Thomas
Publicado 2019

How to design a dose-finding study using the continual reassessment method

por Wheeler, Graham M., Mander, Adrian P., Bedding, Alun, Brock, Kristian, Cornelius, Victoria, Grieve, Andrew P., Jaki, Thomas, Love, Sharon B., Odondi, Lang’o, Weir, Christopher J., Yap, Christina, Bond, Simon J.
Publicado 2019

Adaptive designs in clinical trials: why use them, and how to run and report them

por Pallmann, Philip, Bedding, Alun W., Choodari-Oskooei, Babak, Dimairo, Munyaradzi, Flight, Laura, Hampson, Lisa V., Holmes, Jane, Mander, Adrian P., Odondi, Lang’o, Sydes, Matthew R., Villar, Sofía S., Wason, James M. S., Weir, Christopher J., Wheeler, Graham M., Yap, Christina, Jaki, Thomas
Publicado 2018

Extended and standard duration weight-loss programme referrals for adults in primary care (WRAP): a randomised controlled trial

por Ahern, Amy L, Wheeler, Graham M, Aveyard, Paul, Boyland, Emma J, Halford, Jason C G, Mander, Adrian P, Woolston, Jennifer, Thomson, Ann M, Tsiountsioura, Melina, Cole, Darren, Mead, Bethan R, Irvine, Lisa, Turner, David, Suhrcke, Marc, Pimpin, Laura, Retat, Lise, Jaccard, Abbygail, Webber, Laura, Cohn, Simon R, Jebb, Susan A
Publicado 2017