The Underappreciated Role of Eosinophils in Esophageal Cancer

por Fuller, Annie D., Whelan, Kelly A.
Publicado 2023

Esophageal 3D Culture Systems as Modeling Tools in Esophageal Epithelial Pathobiology and Personalized Medicine

por Whelan, Kelly A., Muir, Amanda B., Nakagawa, Hiroshi
Publicado 2018

Hypoxia Suppression of Bim and Bmf Blocks Anoikis and Luminal Clearing during Mammary Morphogenesis

por Whelan, Kelly A., Caldwell, Sarah A., Shahriari, Kristina S., Jackson, S. RaElle, Franchetti, Lisa D., Johannes, Gregg J., Reginato, Mauricio J.
Publicado 2010

Disruption of Cytochrome c Oxidase Function Induces Warburg Effect and Metabolic Reprogramming

por Srinivasan, Satish, Guha, Manti, Dong, Dawei W, Whelan, Kelly A, Ruthel, Gordon, Uchikado, Yasuto, Natsugoe, Shoji, Nakagawa, Hiroshi, Avadhani, Narayan G.
Publicado 2015

A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice

por Laronda, Monica M., Rutz, Alexandra L., Xiao, Shuo, Whelan, Kelly A., Duncan, Francesca E., Roth, Eric W., Woodruff, Teresa K., Shah, Ramille N.
Publicado 2017

Roles for Autophagy in Esophageal Carcinogenesis: Implications for Improving Patient Outcomes

por Saxena, Reshu, Klochkova, Alena, Murray, Mary Grace, Kabir, Mohammad Faujul, Samad, Safiyah, Beccari, Tyler, Gang, Julie, Patel, Kishan, Hamilton, Kathryn E., Whelan, Kelly A.
Publicado 2019

Eosinophilic esophagitis-associated epithelial remodeling may limit esophageal carcinogenesis

por Fuller, Annie D., Karami, Adam L., Kabir, Mohammad Faujul, Klochkova, Alena, Jackson, Jazmyne L., Mu, Anbin, Tan, Yinfei, Klein-Szanto, Andres J., Whelan, Kelly A.
Publicado 2023

Suprabasal cells retaining stem cell identity programs drive basal cell hyperplasia in eosinophilic esophagitis

por Clevenger, Margarette H., Karami, Adam L., Carlson, Dustin A., Kahrilas, Peter J., Gonsalves, Nirmala, Pandolfino, John E., Winter, Deborah R., Whelan, Kelly A., Tétreault, Marie-Pier
Publicado 2023

Suprabasal cells retain progenitor cell identity programs in eosinophilic esophagitis–driven basal cell hyperplasia

por Clevenger, Margarette H., Karami, Adam L., Carlson, Dustin A., Kahrilas, Peter J., Gonsalves, Nirmala, Pandolfino, John E., Winter, Deborah R., Whelan, Kelly A., Tétreault, Marie-Pier
Publicado 2023

KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF

por Shaverdashvili, Khvaramze, Padlo, Jennie, Weinblatt, Daniel, Jia, Yang, Jiang, Wenpeng, Rao, Divya, Laczkó, Dorottya, Whelan, Kelly A., Lynch, John P., Muir, Amanda B., Katz, Jonathan P.
Publicado 2019

A role for age-associated alterations in esophageal epithelium in eosinophilic esophagitis-associated fibrosis

por Klochkova, Alena, Fuller, Annie D., Miller, Riley, Karami, Adam L., Panchani, Surali R., Natarajan, Shruthi, Mu, Anbin, Jackson, Jazmyne L., Klein-Szanto, Andres J., Muir, Amanda B., Whelan, Kelly A.
Publicado 2022

Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium

por Amanuma, Yusuke, Ohashi, Shinya, Itatani, Yoshiro, Tsurumaki, Mihoko, Matsuda, Shun, Kikuchi, Osamu, Nakai, Yukie, Miyamoto, Shin’ichi, Oyama, Tsunehiro, Kawamoto, Toshihiro, Whelan, Kelly A., Nakagawa, Hiroshi, Chiba, Tsutomu, Matsuda, Tomonari, Muto, Manabu
Publicado 2015

A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis

por Guo, Qian, Xin, Mingyang, Lu, Qingchun, Feng, Dechun, Yang, Vicky, Peng, Lee F., Whelan, Kelly A., Hu, Wenhui, Wu, Sheng, Yang, Xiaofeng, Wang, Hong, Rothberg, Brad S., Gamero, Ana M., Gerhard, Glenn S., Gao, Bin, Yang, Ling
Publicado 2023

Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression

por Kinugasa, Hideaki, Whelan, Kelly A., Tanaka, Koji, Natsuizaka, Mitsuteru, Long, Apple, Guo, Andy, Chang, Sanders, Kagawa, Shingo, Srinivasan, Satish, Guha, Manti, Yamamoto, Kazuhide, St. Clair, Daret K., Avadhani, Narayan G., Diehl, J. Alan, Nakagawa, Hiroshi
Publicado 2015

Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance

por Whelan, Kelly A., Chandramouleeswaran, Prasanna M., Tanaka, Koji, Natsuizaka, Mitsuteru, Guha, Manti, Srinivasan, Satish, Darling, Douglas S., Kita, Yoshiaki, Natsugoe, Shoji, Winkler, Jeffrey D., Klein-Szanto, Andres J., Amaravadi, Ravi K., Avadhani, Narayan G., Rustgi, Anil. K, Nakagawa, Hiroshi
Publicado 2017

Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis

por Sasaki, Masaru, Hara, Takeo, Wang, Joshua X., Zhou, Yusen, Kennedy, Kanak V., Umeweni, Nicole N., Alston, Maiya A., Spergel, Zachary C., Nakagawa, Ritsu, Mcmillan, Emily A., Whelan, Kelly A., Karakasheva, Tatiana A., Hamilton, Kathryn E., Ruffner, Melanie A., Muir, Amanda B.
Publicado 2023

Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor suppressor activities

por Kagawa, Shingo, Natsuizaka, Mitsuteru, Whelan, Kelly A., Facompre, Nicole, Naganuma, Seiji, Ohashi, Shinya, Kinugasa, Hideaki, Egloff, Ann Marie, Basu, Devraj, Gimotty, Phyllis A., Klein-Szanto, Andres J, Bass, Adam, Wong, Kwok-Kin, Diehl, J. Alan, Rustgi, Anil K., Nakagawa, Hiroshi
Publicado 2014

The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes

por Kasagi, Yuta, Chandramouleeswaran, Prasanna M., Whelan, Kelly A., Tanaka, Koji, Giroux, Veronique, Sharma, Medha, Wang, Joshua, Benitez, Alain J., DeMarshall, Maureen, Tobias, John W., Hamilton, Kathryn E., Falk, Gary W., Spergel, Jonathan M., Klein-Szanto, Andres J., Rustgi, Anil K., Muir, Amanda B., Nakagawa, Hiroshi
Publicado 2018

Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes

por Chandramouleeswaran, Prasanna M., Guha, Manti, Shimonosono, Masataka, Whelan, Kelly A., Maekawa, Hisatsugu, Sachdeva, Uma M., Ruthel, Gordon, Mukherjee, Sarmistha, Engel, Noah, Gonzalez, Michael V., Garifallou, James, Ohashi, Shinya, Klein-Szanto, Andres J., Mesaros, Clementina A., Blair, Ian A., Pellegrino da Silva, Renata, Hakonarson, Hakon, Noguchi, Eishi, Baur, Joseph A., Nakagawa, Hiroshi
Publicado 2020

CD73(+) Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis

por Hara, Takeo, Kasagi, Yuta, Wang, Joshua, Sasaki, Masaru, Aaron, Bailey, Karami, Adam, Shimonosono, Masataka, Shimonosono, Rieko, Maekawa, Hisatsugu, Dolinsky, Lauren, Wilkins, Benjamin, Klein, Jeremy, Wei, Jane, Nunes, Kathryn, Lynch, Kristle, Spergel, Jonathan M., Hamilton, Kathryn E., Ruffner, Melanie A., Karakasheva, Tatiana A., Whelan, Kelly A., Nakagawa, Hiroshi, Muir, Amanda B.
Publicado 2022