Animal Models of Drug-Resistant Epilepsy as Tools for Deciphering the Cellular and Molecular Mechanisms of Pharmacoresistance and Discovering More Effective Treatments

por Löscher, Wolfgang, White, H. Steve
Publicado 2023

Brief history of anti‐seizure drug development

por Rho, Jong M., White, H. Steve
Publicado 2018

New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: II. Treatments in Clinical Development

por Perucca, Emilio, White, H. Steve, Bialer, Meir
Publicado 2023

New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: I. Role of GABA as a Modulator of Seizure Activity and Recently Approved Medications Acting on the GABA Sys...

por Perucca, Emilio, Bialer, Meir, White, H. Steve
Publicado 2023

Perampanel’s forgiveness factor in a variable medication adherence paradigm in a rat model of chronic epilepsy

por Guignet, Michelle, Campbell, Amanda, Vuong, Jonathan, Whittington, Dale, White, H. Steve
Publicado 2023

Diurnal burden of spontaneous seizures in early epileptogenesis in the post‐kainic acid rat model of epilepsy

por Mizuno, Stephanie, Koneval, Zachery, Zierath, Dannielle K., Knox, Kevin M., White, H. Steve, Barker‐Haliski, Melissa
Publicado 2021

Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital

por Barker‐Haliski, Melissa, Knox, Kevin, Zierath, Dannielle, Koneval, Zachery, Metcalf, Cameron, Wilcox, Karen S., White, H. Steve
Publicado 2021

Diet composition and sterilization modifies intestinal microbiome diversity and burden of Theiler’s virus infection-induced acute seizures

por Zierath, Dannielle K., Davidson, Stephanie, Manoukian, Jonathan, White, H. Steve, Meeker, Stacey, Ericsson, Aaron, Barker-Haliski, Melissa
Publicado 2023

Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents

por Henshall, David C, Dürmüller, Nick, White, H Steve, Williams, Robert, Moser, Paul, Dunleavy, Mark, Silverstone, Peter H
Publicado 2009

Anticonvulsive properties of soticlestat, a novel cholesterol 24‐hydroxylase inhibitor

por Nishi, Toshiya, Metcalf, Cameron S., Fujimoto, Shinji, Hasegawa, Shigeo, Miyamoto, Maki, Sunahara, Eiji, Watanabe, Sayuri, Kondo, Shinichi, White, H. Steve
Publicado 2022

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects

por Lie, Maria E. K., Kickinger, Stefanie, Skovgaard-Petersen, Jonas, Ecker, Gerhard F., Clausen, Rasmus P., Schousboe, Arne, White, H. Steve, Wellendorph, Petrine
Publicado 2020

Music-Enhanced Analgesia and Antiseizure Activities in Animal Models of Pain and Epilepsy: Toward Preclinical Studies Supporting Development of Digital Therapeutics and Their Combi...

por Metcalf, Cameron S., Huntsman, Merodean, Garcia, Gerry, Kochanski, Adam K., Chikinda, Michael, Watanabe, Eugene, Underwood, Tristan, Vanegas, Fabiola, Smith, Misty D., White, H. Steve, Bulaj, Grzegorz
Publicado 2019

A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties

por Lee, Hee-Kyoung, Zhang, Liuyin, Smith, Misty D., Walewska, Aleksandra, Vellore, Nadeem A., Baron, Riccardo, McIntosh, J. Michael, White, H. Steve, Olivera, Baldomero M., Bulaj, Grzegorz
Publicado 2015

Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models

por Patra, Pabitra Hriday, Barker‐Haliski, Melissa, White, H. Steve, Whalley, Benjamin J., Glyn, Sarah, Sandhu, Haramrit, Jones, Nicholas, Bazelot, Michael, Williams, Claire M., McNeish, Alister James
Publicado 2018

Deconstructing tolerance with clobazam: Post hoc analyses from an open-label extension study

por Gidal, Barry E., Wechsler, Robert T., Sankar, Raman, Montouris, Georgia D., White, H. Steve, Cloyd, James C., Kane, Mary Clare, Peng, Guangbin, Tworek, David M., Shen, Vivienne, Isojarvi, Jouko
Publicado 2016

Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored antiepileptogenesis and...

por Galanopoulou, Aristea S., Löscher, Wolfgang, Lubbers, Laura, O’Brien, Terence J., Staley, Kevin, Vezzani, Annamaria, D’Ambrosio, Raimondo, White, H. Steve, Sontheimer, Harald, Wolf, John A., Twyman, Roy, Whittemore, Vicky, Wilcox, Karen S., Klein, Brian
Publicado 2021

A Role of SCN9A in Human Epilepsies, As a Cause of Febrile Seizures and As a Potential Modifier of Dravet Syndrome

por Singh, Nanda A., Pappas, Chris, Dahle, E. Jill, Claes, Lieve R. F., Pruess, Timothy H., De Jonghe, Peter, Thompson, Joel, Dixon, Missy, Gurnett, Christina, Peiffer, Andy, White, H. Steve, Filloux, Francis, Leppert, Mark F.
Publicado 2009

Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy

por Patel, Dipan C., Wallis, Glenna, Dahle, E. Jill, McElroy, Pallavi B., Thomson, Kyle E., Tesi, Raymond J., Szymkowski, David E., West, Peter J., Smeal, Roy M., Patel, Manisha, Fujinami, Robert S., White, H. Steve, Wilcox, Karen S.
Publicado 2017