Structural principles of SNARE complex recognition by the AAA+ protein NSF

por White, K Ian, Zhao, Minglei, Choi, Ucheor B, Pfuetzner, Richard A, Brunger, Axel T
Publicado 2018

Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle

por Yang, Kailu, Wang, Chuchu, White, K. Ian, Pfuetzner, Richard A., Esquivies, Luis, Brunger, Axel T.
Publicado 2022

NSF-mediated disassembly of on- and off-pathway SNARE complexes and inhibition by complexin

por Choi, Ucheor B, Zhao, Minglei, White, K Ian, Pfuetzner, Richard A, Esquivies, Luis, Zhou, Qiangjun, Brunger, Axel T
Publicado 2018

Calibration of rotation axes for multi-axis goniometers in macromolecular crystallography

por White, K. Ian, Bugris, Valeria, McCarthy, Andrew A., Ravelli, Raimond B. G., Csankó, Krisztián, Cassetta, Alberto, Brockhauser, Sandor
Publicado 2018

Structures of neurexophilin–neurexin complexes reveal a regulatory mechanism of alternative splicing

por Wilson, Steven C, White, K Ian, Zhou, Qiangjun, Pfuetzner, Richard A, Choi, Ucheor B, Südhof, Thomas C, Brunger, Axel T
Publicado 2019

Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor

por Yang, Kailu, Wang, Chuchu, Kreutzberger, Alex J. B., White, K. Ian, Pfuetzner, Richard A., Esquivies, Luis, Kirchhausen, Tomas, Brunger, Axel T.
Publicado 2023

Sensory deficit screen identifies nsf mutation that differentially affects SNARE recycling and quality control

por Gao, Yan, Khan, Yousuf A., Mo, Weike, White, K. Ian, Perkins, Matthew, Pfuetzner, Richard A., Trapani, Josef G., Brunger, Axel T., Nicolson, Teresa
Publicado 2023

Drug discovery targeting SARS-CoV-2 membrane fusion

por Yang, Kailu, Wang, Chuchu, Kreutzberger, Alex J.B., Ojha, Ravi, Kuivanen, Suvi, Couoh-Cardel, Sergio, Muratcioglu, Serena, Eisen, Timothy J., White, K. Ian, Pfuetzner, Richard, Kuriyan, John, Vapalahti, Olli, Balistreri, Giuseppe, Kirchhausen, Tomas, Brunger, Axel T.
Publicado 2023

Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein

por Yang, Kailu, Wang, Chuchu, Kreutzberger, Alex J. B., Ojha, Ravi, Kuivanen, Suvi, Couoh-Cardel, Sergio, Muratcioglu, Serena, Eisen, Timothy J., White, K. Ian, Held, Richard G., Subramanian, Subu, Marcus, Kendra, Pfuetzner, Richard A., Esquivies, Luis, Doyle, Catherine A., Kuriyan, John, Vapalahti, Olli, Balistreri, Giuseppe, Kirchhausen, Tom, Brunger, Axel T.
Publicado 2022