Modulation of CRMP2 via (S)-Lacosamide shows therapeutic promise but is ultimately ineffective in a mouse model of CLN6-Batten disease

por White, Katherine A., Cain, Jacob T., Magee, Helen, Yeon, Seul Ki, Park, Ki Duk, Khanna, Rajesh, Weimer, Jill M.
Publicado 2019

Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female Cln8(mnd) mice

por Holmes, Andrew D., White, Katherine A., Pratt, Melissa A., Johnson, Tyler B., Likhite, Shibi, Meyer, Kathrin, Weimer, Jill M.
Publicado 2022

Development of a tobacco 21 policy assessment tool and state-level analysis in the USA, 2015–2019

por D Dobbs, Page, Chadwick, Ginny, W Ungar, Katherine, M Dunlap, Chris, White, Katherine A, Kelly, Michael CT, K Cheney, Marshall
Publicado 2020

Tracking sex-dependent differences in a mouse model of CLN6-Batten disease

por Poppens, McKayla J., Cain, Jacob T., Johnson, Tyler B., White, Katherine A., Davis, Samantha S., Laufmann, Rachel, Kloth, Alexander D., Weimer, Jill M.
Publicado 2019

Validating indicators of CNS disorders in a swine model of neurological disease

por Swier, Vicki J., White, Katherine A., Meyerholz, David K., Chefdeville, Aude, Khanna, Rajesh, Sieren, Jessica C., Quelle, Dawn E., Weimer, Jill M.
Publicado 2020

Magnetic resonance brain volumetry biomarkers of CLN2 Batten disease identified with miniswine model

por Knoernschild, Kevin, Johnson, Hans J., Schroeder, Kimberly E., Swier, Vicki J., White, Katherine A., Sato, Takashi S., Rogers, Christopher S., Weimer, Jill M., Sieren, Jessica C.
Publicado 2023

Searching for novel biomarkers using a mouse model of CLN3-Batten disease

por Timm, Derek, Cain, Jacob T., Geraets, Ryan D., White, Katherine A., Koh, Seung yon, Kielian, Tammy, Pearce, David A., Hastings, Michelle L., Weimer, Jill M.
Publicado 2018

A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes

por Swier, Vicki J., White, Katherine A., Johnson, Tyler B., Wang, Xiaojun, Han, Jimin, Pearce, David A., Singh, Ruchira, Drack, Arlene V., Pfeifer, Wanda, Rogers, Christopher S., Brudvig, Jon J., Weimer, Jill M.
Publicado 2023

Sortilin inhibition treats multiple neurodegenerative lysosomal storage disorders

por Leppert, Hannah G., Anderson, Joelle T., Timm, Kaylie J., Davoli, Cristina, Pratt, Melissa A., Booth, Clarissa D., White, Katherine A., Rechtzigel, Mitchell J., Meyerink, Brandon L., Johnson, Tyler B., Brudvig, Jon J., Weimer, Jill M.
Publicado 2023

Abbreviated Exposure to Hypoxia Is Sufficient to Induce CNS Dysmyelination, Modulate Spinal Motor Neuron Composition, and Impair Motor Development in Neonatal Mice

por Watzlawik, Jens O., Kahoud, Robert J., O’Toole, Ryan J., White, Katherine A. M., Ogden, Alyssa R., Painter, Meghan M., Wootla, Bharath, Papke, Louisa M., Denic, Aleksandar, Weimer, Jill M., Carey, William A., Rodriguez, Moses
Publicado 2015

Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease

por Johnson, Tyler B., Brudvig, Jon J., Likhite, Shibi, Pratt, Melissa A., White, Katherine A., Cain, Jacob T., Booth, Clarissa D., Timm, Derek J., Davis, Samantha S., Meyerink, Brandon, Pineda, Ricardo, Dennys-Rivers, Cassandra, Kaspar, Brian K., Meyer, Kathrin, Weimer, Jill M.
Publicado 2023

Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice

por White, Katherine A., Nelvagal, Hemanth R., Poole, Timothy A., Lu, Bin, Johnson, Tyler B., Davis, Samantha, Pratt, Melissa A., Brudvig, Jon, Assis, Ana B., Likhite, Shibi, Meyer, Kathrin, Kaspar, Brian K., Cooper, Jonathan D., Wang, Shaomei, Weimer, Jill M.
Publicado 2021

Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease

por Cain, Jacob T., Likhite, Shibi, White, Katherine A., Timm, Derek J., Davis, Samantha S., Johnson, Tyler B., Dennys-Rivers, Cassandra N., Rinaldi, Federica, Motti, Dario, Corcoran, Sarah, Morales, Pablo, Pierson, Christopher, Hughes, Stephanie M., Lee, Stella Y., Kaspar, Brian K., Meyer, Kathrin, Weimer, Jill M.
Publicado 2019