Regulatory T‐cells in helminth infection: induction, function and therapeutic potential

por White, Madeleine P. J., McManus, Caitlin M., Maizels, Rick M.
Publicado 2020

Innate IFN-γ ameliorates experimental autoimmune encephalomyelitis and promotes myeloid expansion and PDL-1 expression

por White, Madeleine P. J., Webster, Gill, Leonard, Faith, La Flamme, Anne Camille
Publicado 2018

Targeting Innate Receptors with MIS416 Reshapes Th Responses and Suppresses CNS Disease in a Mouse Model of Multiple Sclerosis

por White, Madeleine, Webster, Gill, O’Sullivan, David, Stone, Sarrabeth, La Flamme, Anne Camille
Publicado 2014

The parasite cytokine mimic Hp‐TGM potently replicates the regulatory effects of TGF‐β on murine CD4(+) T cells

por White, Madeleine P J, Smyth, Danielle J, Cook, Laura, Ziegler, Steven F, Levings, Megan K, Maizels, Rick M
Publicado 2021

The Helminth Parasite Heligmosomoides polygyrus Attenuates EAE in an IL-4Rα-Dependent Manner

por White, Madeleine P. J., Johnston, Chris J. C., Grainger, John R., Konkel, Joanne E., O'Connor, Richard A., Anderton, Stephen M., Maizels, Rick M.
Publicado 2020

Protection from T cell-dependent colitis by the helminth-derived immunomodulatory mimic of transforming growth factor-β, Hp-TGM

por Smyth, Danielle J, White, Madeleine P J, Johnston, Chris J C, Donachie, Anne-Marie, Campillo Poveda, Marta, McSorley, Henry J, Maizels, Rick M
Publicado 2023

Oral delivery of a functional algal-expressed TGF-β mimic halts colitis in a murine DSS model

por Smyth, Danielle J., Ren, Bijie, White, Madeleine P.J., McManus, Caitlin, Webster, Holly, Shek, Vivien, Evans, Caroline, Pandhal, Jagroop, Fields, Francis, Maizels, Rick M., Mayfield, Stephen
Publicado 2021

The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF)

por Varyani, Fumi, Löser, Stephan, Filbey, Kara J., Harcus, Yvonne, Drurey, Claire, Poveda, Marta Campillo, Rasid, Orhan, White, Madeleine P. J., Smyth, Danielle J., Gerbe, François, Jay, Philippe, Maizels, Rick M.
Publicado 2022

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

por Smyth, Danielle J., Harcus, Yvonne, White, Madeleine P.J., Gregory, William F., Nahler, Janina, Stephens, Ian, Toke-Bjolgerud, Edward, Hewitson, James P., Ivens, Alasdair, McSorley, Henry J., Maizels, Rick M.
Publicado 2018

Induction of stable human FOXP3(+) Tregs by a parasite‐derived TGF‐β mimic

por Cook, Laura, Reid, Kyle T, Häkkinen, Elmeri, de Bie, Brett, Tanaka, Shigeru, Smyth, Danielle J, White, Madeleine PJ, Wong, May Q, Huang, Qing, Gillies, Jana K, Ziegler, Steven F., Maizels, Rick M, Levings, Megan K
Publicado 2021

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

por Oftedal, Bergithe E., Maio, Stefano, Handel, Adam E., White, Madeleine P. J., Howie, Duncan, Davis, Simon, Prevot, Nicolas, Rota, Ioanna A., Deadman, Mary E., Kessler, Benedikt M., Fischer, Roman, Trede, Nikolaus S., Sezgin, Erdinc, Maizels, Rick M., Holländer, Georg A.
Publicado 2021

CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic

por van Dinther, Maarten, Cunningham, Kyle T., Singh, Shashi Prakash, White, Madeleine P. J., Campion, Tiffany, Ciancia, Claire, van Veelen, Peter A., de Ru, Arnoud H., González-Prieto, Román, Mukundan, Ananya, Byeon, Chang-Hyeock, Staggers, Sophia R., Hinck, Cynthia S., Hinck, Andrew P., Dijke, Peter ten, Maizels, Rick M.
Publicado 2023

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

por Johnston, Chris J. C., Smyth, Danielle J., Kodali, Ravindra B., White, Madeleine P. J., Harcus, Yvonne, Filbey, Kara J., Hewitson, James P., Hinck, Cynthia S., Ivens, Alasdair, Kemter, Andrea M., Kildemoes, Anna O., Le Bihan, Thierry, Soares, Dinesh C., Anderton, Stephen M., Brenn, Thomas, Wigmore, Stephen J., Woodcock, Hannah V., Chambers, Rachel C., Hinck, Andrew P., McSorley, Henry J., Maizels, Rick M.
Publicado 2017