CNTN5(-)(/+)or EHMT2(-)(/+)human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks

por Deneault, Eric, Faheem, Muhammad, White, Sean H, Rodrigues, Deivid C, Sun, Song, Wei, Wei, Piekna, Alina, Thompson, Tadeo, Howe, Jennifer L, Chalil, Leon, Kwan, Vickie, Walker, Susan, Pasceri, Peter, Roth, Frederick P, Yuen, Ryan KC, Singh, Karun K, Ellis, James, Scherer, Stephen W
Publicado 2019

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

por Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Publicado 2018

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

por Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Publicado 2019

OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome

por Uddin, Mohammed, Unda, Brianna K., Kwan, Vickie, Holzapfel, Nicholas T., White, Sean H., Chalil, Leon, Woodbury-Smith, Marc, Ho, Karen S., Harward, Erin, Murtaza, Nadeem, Dave, Biren, Pellecchia, Giovanna, D’Abate, Lia, Nalpathamkalam, Thomas, Lamoureux, Sylvia, Wei, John, Speevak, Marsha, Stavropoulos, James, Hope, Kristin J., Doble, Brad W., Nielsen, Jacob, Wassman, E. Robert, Scherer, Stephen W., Singh, Karun K.
Publicado 2018

Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling

por Richter, Melanie, Murtaza, Nadeem, Scharrenberg, Robin, White, Sean H., Johanns, Ole, Walker, Susan, Yuen, Ryan K. C., Schwanke, Birgit, Bedürftig, Bianca, Henis, Melad, Scharf, Sarah, Kraus, Vanessa, Dörk, Ronja, Hellmann, Jakob, Lindenmaier, Zsuzsa, Ellegood, Jacob, Hartung, Henrike, Kwan, Vickie, Sedlacik, Jan, Fiehler, Jens, Schweizer, Michaela, Lerch, Jason P., Hanganu-Opatz, Ileana L., Morellini, Fabio, Scherer, Stephen W., Singh, Karun K., Calderon de Anda, Froylan
Publicado 2018