How the BRAF V600E Mutation Defines a Distinct Subgroup of Colorectal Cancer: Molecular and Clinical Implications

por Bond, Catherine E., Whitehall, Vicki L. J.
Publicado 2018

The Therapeutic Landscape for KRAS-Mutated Colorectal Cancers

por Tria, Simon Manuel, Burge, Matthew E., Whitehall, Vicki L. J.
Publicado 2023

The Efficacy of Using Patient-Derived Organoids to Predict Treatment Response in Colorectal Cancer

por Su, Chang, Olsen, Kelly A., Bond, Catherine E., Whitehall, Vicki L. J.
Publicado 2023

Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

por Rosty, Christophe, Hewett, David G., Brown, Ian S., Leggett, Barbara A., Whitehall, Vicki L. J.
Publicado 2012

Chromosomal Instability in BRAF Mutant, Microsatellite Stable Colorectal Cancers

por Bond, Catherine E., Umapathy, Aarti, Buttenshaw, Ron L., Wockner, Leesa, Leggett, Barbara A., Whitehall, Vicki L. J.
Publicado 2012

DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas

por Liu, Cheng, Fennell, Lochlan J., Bettington, Mark L., Walker, Neal I., Dwine, Joel, Leggett, Barbara A., Whitehall, Vicki L. J.
Publicado 2019

Microsatellite Stable Colorectal Cancers Stratified by the BRAF V600E Mutation Show Distinct Patterns of Chromosomal Instability

por Bond, Catherine E., Nancarrow, Derek J., Wockner, Leesa F., Wallace, Leanne, Montgomery, Grant W., Leggett, Barbara A., Whitehall, Vicki L. J.
Publicado 2014

Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysis

por Fennell, Lochlan J., Hartel, Gunter, McKeone, Diane M., Bond, Catherine E., Kane, Alexandra, Leggett, Barbara A., Patch, Ann-Marie, Whitehall, Vicki L.J.
Publicado 2022

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis

por Bond, Catherine E., McKeone, Diane M., Kalimutho, Murugan, Bettington, Mark L., Pearson, Sally-Ann, Dumenil, Troy D., Wockner, Leesa F., Burge, Matthew, Leggett, Barbara A., Whitehall, Vicki L.J.
Publicado 2016

Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer

por Kane, Alexandra M., Fennell, Lochlan J., Liu, Cheng, Borowsky, Jennifer, McKeone, Diane M., Bond, Catherine E., Kazakoff, Stephen, Patch, Ann-Marie, Koufariotis, Lambros T., Pearson, John, Waddell, Nicola, Leggett, Barbara A., Whitehall, Vicki L.J.
Publicado 2020

APC Mutation Marks an Aggressive Subtype of BRAF Mutant Colorectal Cancers

por Fennell, Lochlan J., Kane, Alexandra, Liu, Cheng, McKeone, Diane, Fernando, Winnie, Su, Chang, Bond, Catherine, Jamieson, Saara, Dumenil, Troy, Patch, Ann-Marie, Kazakoff, Stephen H., Pearson, John V., Waddell, Nicola, Leggett, Barbara, Whitehall, Vicki L. J.
Publicado 2020

Global Methylome Scores Correlate with Histological Subtypes of Colorectal Carcinoma and Show Different Associations with Common Clinical and Molecular Features

por Turpín-Sevilla, María del Carmen, Pérez-Sanz, Fernando, García-Solano, José, Sebastián-León, Patricia, Trujillo-Santos, Javier, Carbonell, Pablo, Estrada, Eduardo, Tuomisto, Anne, Herruzo, Irene, Fennell, Lochlan J., Mäkinen, Markus J., Rodríguez-Braun, Edith, Whitehall, Vicki L. J., Conesa, Ana, Conesa-Zamora, Pablo
Publicado 2021

Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia

por Bond, Catherine E., Liu, Cheng, Kawamata, Futoshi, McKeone, Diane M., Fernando, Winnie, Jamieson, Saara, Pearson, Sally-Ann, Kane, Alexandra, Woods, Susan L., Lannagan, Tamsin R. M., Somashekar, Roshini, Lee, Young, Dumenil, Troy, Hartel, Gunter, Spring, Kevin J., Borowsky, Jennifer, Fennell, Lochlan, Bettington, Mark, Lee, Jason, Worthley, Daniel L., Leggett, Barbara A., Whitehall, Vicki L. J.
Publicado 2018

Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression

por Luk, Ian Y., Jenkins, Laura J., Schoffer, Kael L., Ng, Irvin, Tse, Janson W. T., Mouradov, Dmitri, Kaczmarczyk, Stanislaw, Nightingale, Rebecca, Burrows, Allan D., Anderson, Robin L., Arango, Diego, Dopeso, Higinio, Croft, Larry, Richardson, Mark F., Sieber, Oliver M., Liao, Yang, Mooi, Jennifer K., Vukelic, Natalia, Reehorst, Camilla M., Afshar-Sterle, Shoukat, Whitehall, Vicki L. J., Fennell, Lochlan, Abud, Helen E., Tebbutt, Niall C., Phillips, Wayne A., Williams, David S., Shi, Wei, Mielke, Lisa A., Ernst, Matthias, Dhillon, Amardeep S., Clemons, Nicholas J., Mariadason, John M.
Publicado 2022