Comparison of Statistical Tests for Association between Rare Variants and Binary Traits

por Bacanu, Silviu-Alin, Nelson, Matthew R., Whittaker, John C.
Publicado 2012

The impact of targeting all elderly persons in England and Wales for yearly influenza vaccination: excess mortality due to pneumonia or influenza and time trend study

por Mann, Andrea G, Mangtani, Punam, Russell, Colin A, Whittaker, John C
Publicado 2013

Variance components linkage analysis for adjusted systolic blood pressure in the Framingham Heart Study

por Byng, Martyn C, Fisher, Sheila A, Lewis, Cathryn M, Whittaker, John C
Publicado 2003

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies

por Hoggart, Clive J., Whittaker, John C., De Iorio, Maria, Balding, David J.
Publicado 2008

Evaluation of Genetic Markers as Instruments for Mendelian Randomization Studies on Vitamin D

por Berry, Diane J., Vimaleswaran, Karani S., Whittaker, John C., Hingorani, Aroon D., Hyppönen, Elina
Publicado 2012

Genetic association analysis of vitamin D pathway with obesity traits

por Vimaleswaran, Karani Santhanakrishnan, Cavadino, Alana, Berry, Diane J, Whittaker, John C, Power, Chris, Järvelin, Marjo-Riitta, Hyppönen, Elina
Publicado 2013

Fregene: Simulation of realistic sequence-level data in populations and ascertained samples

por Chadeau-Hyam, Marc, Hoggart, Clive J, O'Reilly, Paul F, Whittaker, John C, De Iorio, Maria, Balding, David J
Publicado 2008

Selecting instruments for Mendelian randomization in the wake of genome-wide association studies

por Swerdlow, Daniel I, Kuchenbaecker, Karoline B, Shah, Sonia, Sofat, Reecha, Holmes, Michael V, White, Jon, Mindell, Jennifer S, Kivimaki, Mika, Brunner, Eric J, Whittaker, John C, Casas, Juan P, Hingorani, Aroon D
Publicado 2016

Performance of Genotype Imputation for Rare Variants Identified in Exons and Flanking Regions of Genes

por Li, Li, Li, Yun, Browning, Sharon R., Browning, Brian L., Slater, Andrew J., Kong, Xiangyang, Aponte, Jennifer L., Mooser, Vincent E., Chissoe, Stephanie L., Whittaker, John C., Nelson, Matthew R., Ehm, Margaret Gelder
Publicado 2011

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits

por Silverwood, Richard J, Holmes, Michael V, Dale, Caroline E, Lawlor, Debbie A, Whittaker, John C, Smith, George Davey, Leon, David A, Palmer, Tom, Keating, Brendan J, Zuccolo, Luisa, Casas, Juan P, Dudbridge, Frank
Publicado 2014

Genetic risk factors for variant Creutzfeldt–Jakob disease: a genome-wide association study

por Mead, Simon, Poulter, Mark, Uphill, James, Beck, John, Whitfield, Jerome, Webb, Thomas EF, Campbell, Tracy, Adamson, Gary, Deriziotis, Pelagia, Tabrizi, Sarah J, Hummerich, Holger, Verzilli, Claudio, Alpers, Michael P, Whittaker, John C, Collinge, John
Publicado 2009

The role and interaction of imprinted genes in human fetal growth

por Moore, Gudrun E., Ishida, Miho, Demetriou, Charalambos, Al-Olabi, Lara, Leon, Lydia J., Thomas, Anna C., Abu-Amero, Sayeda, Frost, Jennifer M., Stafford, Jaime L., Chaoqun, Yao, Duncan, Andrew J., Baigel, Rachel, Brimioulle, Marina, Iglesias-Platas, Isabel, Apostolidou, Sophia, Aggarwal, Reena, Whittaker, John C., Syngelaki, Argyro, Nicolaides, Kypros H., Regan, Lesley, Monk, David, Stanier, Philip
Publicado 2015

Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation

por Warren, Liling L., Li, Li, Nelson, Matthew R., Ehm, Margaret G., Shen, Judong, Fraser, Dana J., Aponte, Jennifer L., Nangle, Keith L., Slater, Andrew J., Woollard, Peter M., Hall, Matt D., Topp, Simon D., Yuan, Xin, Cardon, Lon R., Chissoe, Stephanie L., Mooser, Vincent, Morris, Andrew D., Palmer, Colin N.A., Perry, John R., Frayling, Timothy M., Whittaker, John C., Waterworth, Dawn M.
Publicado 2012

Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes

por Talmud, Philippa J., Cooper, Jackie A., Morris, Richard W., Dudbridge, Frank, Shah, Tina, Engmann, Jorgen, Dale, Caroline, White, Jon, McLachlan, Stela, Zabaneh, Delilah, Wong, Andrew, Ong, Ken K., Gaunt, Tom, Holmes, Michael V., Lawlor, Debbie A., Richards, Marcus, Hardy, Rebecca, Kuh, Diana, Wareham, Nicholas, Langenberg, Claudia, Ben-Shlomo, Yoav, Wannamethee, S. Goya, Strachan, Mark W.J., Kumari, Meena, Whittaker, John C., Drenos, Fotios, Kivimaki, Mika, Hingorani, Aroon D., Price, Jacqueline F., Humphries, Steve E.
Publicado 2015

Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

por Shah, Tina, Engmann, Jorgen, Dale, Caroline, Shah, Sonia, White, Jon, Giambartolomei, Claudia, McLachlan, Stela, Zabaneh, Delilah, Cavadino, Alana, Finan, Chris, Wong, Andrew, Amuzu, Antoinette, Ong, Ken, Gaunt, Tom, Holmes, Michael V., Warren, Helen, Davies, Teri-Louise, Drenos, Fotios, Cooper, Jackie, Sofat, Reecha, Caulfield, Mark, Ebrahim, Shah, Lawlor, Debbie A., Talmud, Philippa J., Humphries, Steve E., Power, Christine, Hypponen, Elina, Richards, Marcus, Hardy, Rebecca, Kuh, Diana, Wareham, Nicholas, Ben-Shlomo, Yoav, Day, Ian N., Whincup, Peter, Morris, Richard, Strachan, Mark W. J., Price, Jacqueline, Kumari, Meena, Kivimaki, Mika, Plagnol, Vincent, Dudbridge, Frank, Whittaker, John C., Casas, Juan P., Hingorani, Aroon D.
Publicado 2013

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consorti...

por Shah, Tina, Engmann, Jorgen, Dale, Caroline, Shah, Sonia, White, Jon, Giambartolomei, Claudia, McLachlan, Stela, Zabaneh, Delilah, Cavadino, Alana, Finan, Chris, Wong, Andrew, Amuzu, Antoinette, Ong, Ken, Gaunt, Tom, Holmes, Michael V., Warren, Helen, Davies, Teri-Louise, Drenos, Fotios, Cooper, Jackie, Sofat, Reecha, Caulfield, Mark, Ebrahim, Shah, Lawlor, Debbie A., Talmud, Philippa J., Humphries, Steve E., Power, Christine, Hypponen, Elina, Richards, Marcus, Hardy, Rebecca, Kuh, Diana, Wareham, Nicholas, Ben-Shlomo, Yoav, Day, Ian N., Whincup, Peter, Morris, Richard, Strachan, Mark W. J., Price, Jacqueline, Kumari, Meena, Kivimaki, Mika, Plagnol, Vincent, Dudbridge, Frank, Whittaker, John C., Casas, Juan P., Hingorani, Aroon D.
Publicado 2013

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

por Angelakopoulou, Aspasia, Shah, Tina, Sofat, Reecha, Shah, Sonia, Berry, Diane J., Cooper, Jackie, Palmen, Jutta, Tzoulaki, Ioanna, Wong, Andrew, Jefferis, Barbara J., Maniatis, Nikolas, Drenos, Fotios, Gigante, Bruna, Hardy, Rebecca, Laxton, Ross C., Leander, Karin, Motterle, Anna, Simpson, Iain A., Smeeth, Liam, Thomson, Andy, Verzilli, Claudio, Kuh, Diana, Ireland, Helen, Deanfield, John, Caulfield, Mark, Wallace, Chris, Samani, Nilesh, Munroe, Patricia B., Lathrop, Mark, Fowkes, F. Gerry R., Marmot, Michael, Whincup, Peter H., Whittaker, John C., de Faire, Ulf, Kivimaki, Mika, Kumari, Meena, Hypponen, Elina, Power, Chris, Humphries, Steve E., Talmud, Philippa J., Price, Jackie, Morris, Richard W., Ye, Shu, Casas, Juan P., Hingorani, Aroon D.
Publicado 2012

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

por White, Jon, Sofat, Reecha, Hemani, Gibran, Shah, Tina, Engmann, Jorgen, Dale, Caroline, Shah, Sonia, Kruger, Felix A, Giambartolomei, Claudia, Swerdlow, Daniel I, Palmer, Tom, McLachlan, Stela, Langenberg, Claudia, Zabaneh, Delilah, Lovering, Ruth, Cavadino, Alana, Jefferis, Barbara, Finan, Chris, Wong, Andrew, Amuzu, Antoinette, Ong, Ken, Gaunt, Tom R, Warren, Helen, Davies, Teri-Louise, Drenos, Fotios, Cooper, Jackie, Ebrahim, Shah, Lawlor, Debbie A, Talmud, Philippa J, Humphries, Steve E, Power, Christine, Hypponen, Elina, Richards, Marcus, Hardy, Rebecca, Kuh, Diana, Wareham, Nicholas, Ben-Shlomo, Yoav, Day, Ian N, Whincup, Peter, Morris, Richard, Strachan, Mark W J, Price, Jacqueline, Kumari, Meena, Kivimaki, Mika, Plagnol, Vincent, Whittaker, John C, Smith, George Davey, Dudbridge, Frank, Casas, Juan P, Holmes, Michael V, Hingorani, Aroon D
Publicado 2016

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

por Holmes, Michael V, Newcombe, Paul, Hubacek, Jaroslav A, Sofat, Reecha, Ricketts, Sally L, Cooper, Jackie, Breteler, Monique MB, Bautista, Leonelo E, Sharma, Pankaj, Whittaker, John C, Smeeth, Liam, Fowkes, F Gerald R, Algra, Ale, Shmeleva, Veronika, Szolnoki, Zoltan, Roest, Mark, Linnebank, Michael, Zacho, Jeppe, Nalls, Michael A, Singleton, Andrew B, Ferrucci, Luigi, Hardy, John, Worrall, Bradford B, Rich, Stephen S, Matarin, Mar, Norman, Paul E, Flicker, Leon, Almeida, Osvaldo P, van Bockxmeer, Frank M, Shimokata, Hiroshi, Khaw, Kay-Tee, Wareham, Nicholas J, Bobak, Martin, Sterne, Jonathan AC, Smith, George Davey, Talmud, Philippa J, van Duijn, Cornelia, Humphries, Steve E, Price, Jackie F, Ebrahim, Shah, Lawlor, Debbie A, Hankey, Graeme J, Meschia, James F, Sandhu, Manjinder S, Hingorani, Aroon D, Casas, Juan P
Publicado 2011

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts

por Vimaleswaran, Karani S., Berry, Diane J., Lu, Chen, Tikkanen, Emmi, Pilz, Stefan, Hiraki, Linda T., Cooper, Jason D., Dastani, Zari, Li, Rui, Houston, Denise K., Wood, Andrew R., Michaëlsson, Karl, Vandenput, Liesbeth, Zgaga, Lina, Yerges-Armstrong, Laura M., McCarthy, Mark I., Dupuis, Josée, Kaakinen, Marika, Kleber, Marcus E., Jameson, Karen, Arden, Nigel, Raitakari, Olli, Viikari, Jorma, Lohman, Kurt K., Ferrucci, Luigi, Melhus, Håkan, Ingelsson, Erik, Byberg, Liisa, Lind, Lars, Lorentzon, Mattias, Salomaa, Veikko, Campbell, Harry, Dunlop, Malcolm, Mitchell, Braxton D., Herzig, Karl-Heinz, Pouta, Anneli, Hartikainen, Anna-Liisa, Streeten, Elizabeth A., Theodoratou, Evropi, Jula, Antti, Wareham, Nicholas J., Ohlsson, Claes, Frayling, Timothy M., Kritchevsky, Stephen B., Spector, Timothy D., Richards, J. Brent, Lehtimäki, Terho, Ouwehand, Willem H., Kraft, Peter, Cooper, Cyrus, März, Winfried, Power, Chris, Loos, Ruth J. F., Wang, Thomas J., Järvelin, Marjo-Riitta, Whittaker, John C., Hingorani, Aroon D., Hyppönen, Elina
Publicado 2013