Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies

por Temple, William C, Nix, Matthew A, Naik, Akul, Izgutdina, Adila, Huang, Benjamin J, Wicaksono, Gianina, Phojanakong, Paul, Serrano, Juan Antonio Camara, Young, Elizabeth P, Ramos, Emilio, Salangsang, Fernando, Steri, Veronica, Xirenayi, Simayijiang, Hermiston, Michelle, Logan, Aaron C, Stieglitz, Elliot, Wiita, Arun P
Publicado 2023

Structural surfaceomics reveals an AML-specific conformation of integrin β(2) as a CAR T cellular therapy target

por Mandal, Kamal, Wicaksono, Gianina, Yu, Clinton, Adams, Jarrett J., Hoopmann, Michael R., Temple, William C., Izgutdina, Adila, Escobar, Bonell Patiño, Gorelik, Maryna, Ihling, Christian H., Nix, Matthew A., Naik, Akul, Xie, William H., Hübner, Juwita, Rollins, Lisa A., Reid, Sandy M., Ramos, Emilio, Kasap, Corynn, Steri, Veronica, Serrano, Juan Antonio Camara, Salangsang, Fernando, Phojanakong, Paul, McMillan, Melanie, Gavallos, Victor, Leavitt, Andrew D., Logan, Aaron C., Rooney, Cliona M., Eyquem, Justin, Sinz, Andrea, Huang, Benjamin J., Stieglitz, Elliot, Smith, Catherine C., Moritz, Robert L., Sidhu, Sachdev S., Huang, Lan, Wiita, Arun P.
Publicado 2023