Major Histocompatibility Complex–linked Control of Autoimmunity

por Wicker, Linda S.
Publicado 1997

Adaptive dose-finding designs to identify multiple doses that achieve multiple response targets

por Bond, Simon, Mander, Adrian, Todd, John, Wicker, Linda, Waldron-Lynch, Frank
Publicado 2013

Simulation work in adaptive dose-finding designs to identify dose-intervals that achieve targets in multiple endpoints

por Howlett, James, Bond, Simon, Mander, Adrian, Todd, John, Wicker, Linda, Waldron-Lynch, Frank
Publicado 2015

Fluorescence Intensity Normalisation: Correcting for Time Effects in Large-Scale Flow Cytometric Analysis

por Dendrou, Calliope A., Fung, Erik, Esposito, Laura, Todd, John A., Wicker, Linda S., Plagnol, Vincent
Publicado 2009

The Soluble CTLA-4 Splice Variant Protects From Type 1 Diabetes and Potentiates Regulatory T-Cell Function

por Gerold, Kay D., Zheng, Peilin, Rainbow, Daniel B., Zernecke, Alma, Wicker, Linda S., Kissler, Stephan
Publicado 2011

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

por Trzupek, Dominik, Lee, Mercede, Hamey, Fiona, Wicker, Linda S., Todd, John A., Ferreira, Ricardo C.
Publicado 2022

Slc11a1 Enhances the Autoimmune Diabetogenic T-Cell Response by Altering Processing and Presentation of Pancreatic Islet Antigens

por Dai, Yang D., Marrero, Idania G., Gros, Philippe, Zaghouani, Habib, Wicker, Linda S., Sercarz, Eli E.
Publicado 2009

Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases

por Asimit, Jennifer L., Rainbow, Daniel B., Fortune, Mary D., Grinberg, Nastasiya F., Wicker, Linda S., Wallace, Chris
Publicado 2019

SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile

por Zhang, Jia-Yuan, Whalley, Justin P., Knight, Julian C., Wicker, Linda S., Todd, John A., Ferreira, Ricardo C.
Publicado 2023

Cellular Mechanisms of Restored β-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5

por Hamilton-Williams, Emma E., Cheung, Jocelyn, Rainbow, Daniel B., Hunter, Kara M., Wicker, Linda S., Sherman, Linda A.
Publicado 2012

Rationale and study design of the Adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D): a non-randomised, open label, adaptive dose finding trial

por Waldron-Lynch, Frank, Kareclas, Paula, Irons, Kathryn, Walker, Neil M, Mander, Adrian, Wicker, Linda S, Todd, John A, Bond, Simon
Publicado 2014

CD56(bright) natural killer cells preferentially kill proliferating CD4(+) T cells

por Lee, Mercede, Bell, Charles J M, Rubio Garcia, Arcadio, Godfrey, Leila, Pekalski, Marcin, Wicker, Linda S, Todd, John A, Ferreira, Ricardo C
Publicado 2023

Idd9.2 and Idd9.3 Protective Alleles Function in CD4(+) T-Cells and Nonlymphoid Cells to Prevent Expansion of Pathogenic Islet-Specific CD8(+) T-Cells

por Hamilton-Williams, Emma E., Wong, S.B. Justin, Martinez, Xavier, Rainbow, Daniel B., Hunter, Kara M., Wicker, Linda S., Sherman, Linda A.
Publicado 2010

Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD): a phase 2, multicentre, double-blind, randomized, placebo-controlled trial

por Marcovecchio, M. Loredana, Wicker, Linda S., Dunger, David B., Dutton, Susan J., Kopijasz, Sylwia, Scudder, Claire, Todd, John A., Johnson, Paul R. V.
Publicado 2020

The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes

por Steward, Charles A., Gonzalez, Jose M., Trevanion, Steve, Sheppard, Dan, Kerry, Giselle, Gilbert, James G. R., Wicker, Linda S., Rogers, Jane, Harrow, Jennifer L.
Publicado 2013

Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice

por Mangada, Julie, Pearson, Todd, Brehm, Michael A., Wicker, Linda S., Peterson, Laurence B., Shultz, Leonard D., Serreze, David V., Rossini, Aldo A., Greiner, Dale L.
Publicado 2009

Idd9.1 Locus Controls the Suppressive Activity of FoxP3(+)CD4(+)CD25(+) Regulatory T-Cells

por Yamanouchi, Jun, Puertas, Maria-Carmen, Verdaguer, Joan, Lyons, Paul A., Rainbow, Daniel B., Chamberlain, Giselle, Hunter, Kara M., Peterson, Laurence B., Wicker, Linda S., Santamaria, Pere
Publicado 2010

Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity

por Hamilton-Williams, Emma E., Rainbow, Daniel B., Cheung, Jocelyn, Christensen, Mikkel, Lyons, Paul A., Peterson, Laurence B., Steward, Charles A., Sherman, Linda A., Wicker, Linda S.
Publicado 2013

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment

por Ferreira, Ricardo C., Rainbow, Daniel B., Rubio García, Arcadio, Pekalski, Marcin L., Porter, Linsey, Oliveira, João J., Waldron-Lynch, Frank, Wicker, Linda S., Todd, John A.
Publicado 2017

Human IL-6R(hi)TIGIT(−) CD4(+) CD127(low)CD25(+) T cells display potent in vitro suppressive capacity and a distinct Th17 profile

por Ferreira, Ricardo C., Rainbow, Daniel B., Rubio García, Arcadio, Pekalski, Marcin L., Porter, Linsey, Oliveira, João J., Waldron-Lynch, Frank, Wicker, Linda S., Todd, John A.
Publicado 2017