E- and P-Selectins Are Essential for Repopulation of Chronic Myelogenous and Chronic Eosinophilic Leukemias in a Scid Mouse Xenograft Model

por Wicklein, Daniel, Schmidt, Anna, Labitzky, Vera, Ullrich, Sebastian, Valent, Peter, Schumacher, Udo
Publicado 2013

SDA, a DNA Aptamer Inhibiting E- and P-Selectin Mediated Adhesion of Cancer and Leukemia Cells, the First and Pivotal Step in Transendothelial Migration during Metastasis Formation

por Faryammanesh, Rassa, Lange, Tobias, Magbanua, Eileen, Haas, Sina, Meyer, Cindy, Wicklein, Daniel, Schumacher, Udo, Hahn, Ulrich
Publicado 2014

Antibody Directed against Human YKL-40 Increases Tumor Volume in a Human Melanoma Xenograft Model in Scid Mice

por Salamon, Johannes, Hoffmann, Tatjana, Elies, Eva, Peldschus, Kersten, Johansen, Julia S., Lüers, Georg, Schumacher, Udo, Wicklein, Daniel
Publicado 2014

Nilotinib and Imatinib Are Comparably Effective in Reducing Growth of Human Eosinophil Leukemia Cells in a Newly Established Xenograft Model

por Wicklein, Daniel, Ramos Leal, Nuno, Salamon, Johannes, Thamer, Mohammed, Herrmann, Harald, Valent, Peter, Schumacher, Udo, Ullrich, Sebastian
Publicado 2012

LAMA4-Regulating miR-4274 and Its Host Gene SORCS2 Play a Role in IGFBP6-Dependent Effects on Phenotype of Basal-Like Breast Cancer

por Shkurnikov, Maxim, Nikulin, Sergey, Nersisyan, Stepan, Poloznikov, Andrey, Zaidi, Shan, Baranova, Ancha, Schumacher, Udo, Wicklein, Daniel, Tonevitsky, Alexander
Publicado 2019

Carcinoembryonic Antigen-Related Cell Adhesion Molecules (CEACAM) 1, 5 and 6 as Biomarkers in Pancreatic Cancer

por Gebauer, Florian, Wicklein, Daniel, Horst, Jennifer, Sundermann, Philipp, Maar, Hanna, Streichert, Thomas, Tachezy, Michael, Izbicki, Jakob R., Bockhorn, Maximilian, Schumacher, Udo
Publicado 2014

Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells

por Nikulin, Sergey, Zakharova, Galina, Poloznikov, Andrey, Raigorodskaya, Maria, Wicklein, Daniel, Schumacher, Udo, Nersisyan, Stepan, Bergquist, Jonas, Bakalkin, Georgy, Astakhova, Lidiia, Tonevitsky, Alexander
Publicado 2021

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

por Velthaus, Arne, Cornils, Kerstin, Hennigs, Jan K., Grüb, Saskia, Stamm, Hauke, Wicklein, Daniel, Bokemeyer, Carsten, Heuser, Michael, Windhorst, Sabine, Fiedler, Walter, Wellbrock, Jasmin
Publicado 2019

Identification of potential classes of glycoligands mediating dynamic endothelial adhesion of human tumor cells

por Starzonek, Sarah, Maar, Hanna, Mereiter, Stefan, Freytag, Vera, Haider, Marie-Therese, Riecken, Kristoffer, Huang, Yen-Lin, Jacob, Francis, Wicklein, Daniel, Schumacher, Udo, Lange, Tobias
Publicado 2023

Molecular Changes in Pre-Metastatic Lymph Nodes of Esophageal Cancer Patients

por Otto, Benjamin, Koenig, Alexandra M., Tolstonog, Genrich V., Jeschke, Anke, Klaetschke, Kristin, Vashist, Yogesh K., Wicklein, Daniel, Wagener, Christoph, Izbicki, Jakob R., Streichert, Thomas
Publicado 2014

CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells

por Wicklein, Daniel, Otto, Benjamin, Suling, Anna, Elies, Eva, Lüers, Georg, Lange, Tobias, Feldhaus, Susanne, Maar, Hanna, Schröder-Schwarz, Jennifer, Brunner, Georg, Wagener, Christoph, Schumacher, Udo
Publicado 2018

Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions

por Starzonek, Sarah, Maar, Hanna, Labitzky, Vera, Wicklein, Daniel, Rossdam, Charlotte, Buettner, Falk F R, Wolters-Eisfeld, Gerrit, Guengoer, Cenap, Wagener, Christoph, Schumacher, Udo, Lange, Tobias
Publicado 2020

Fra-2 overexpression upregulates pro-metastatic cell-adhesion molecules, promotes pulmonary metastasis, and reduces survival in a spontaneous xenograft model of human breast cancer

por Arnold, Sabrina, Kortland, Jan, Maltseva, Diana V., Nersisyan, Stepan A., Samatov, Timur R., Lezius, Susanne, Tonevitsky, Alexander G., Milde-Langosch, Karin, Wicklein, Daniel, Schumacher, Udo, Stürken, Christine
Publicado 2021

Selectins Mediate Small Cell Lung Cancer Systemic Metastasis

por Heidemann, Franziska, Schildt, Anna, Schmid, Katharina, Bruns, Oliver T., Riecken, Kristoffer, Jung, Caroline, Ittrich, Harald, Wicklein, Daniel, Reimer, Rudolph, Fehse, Boris, Heeren, Joerg, Lüers, Georg, Schumacher, Udo, Heine, Markus
Publicado 2014

Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression

por Kemper, Marius, Schiecke, Alina, Maar, Hanna, Nikulin, Sergey, Poloznikov, Andrey, Galatenko, Vladimir, Tachezy, Michael, Gebauer, Florian, Lange, Tobias, Riecken, Kristoffer, Tonevitsky, Alexander, Aigner, Achim, Izbicki, Jakob, Schumacher, Udo, Wicklein, Daniel
Publicado 2021

Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy

por Ernst, Ann-Kathrin, Putscher, Annika, Samatov, Timur R., Suling, Anna, Galatenko, Vladimir V., Shkurnikov, Maxim Yu, Knyazev, Evgeny N., Tonevitsky, Alexander G., Haalck, Thomas, Lange, Tobias, Maar, Hanna, Schröder- Schwarz, Jennifer, Riecken, Kristoffer, Schumacher, Udo, Wicklein, Daniel
Publicado 2018

Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung

por Kalinina, Tatyana, Güngör, Cenap, Thieltges, Sabrina, Möller-Krull, Maren, Murga Penas, Eva Maria, Wicklein, Daniel, Streichert, Thomas, Schumacher, Udo, Kalinin, Viacheslav, Simon, Ronald, Otto, Benjamin, Dierlamm, Judith, Schwarzenbach, Heidi, Effenberger, Katharina E, Bockhorn, Maximilian, Izbicki, Jakob R, Yekebas, Emre F
Publicado 2010

Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo

por Lange, Tobias, Valentiner, Ursula, Wicklein, Daniel, Maar, Hanna, Labitzky, Vera, Ahlers, Ann-Kristin, Starzonek, Sarah, Genduso, Sandra, Staffeldt, Lisa, Pahlow, Carolin, Dück, Anna-Maria, Stürken, Christine, Baranowsky, Anke, Bauer, Alexander T., Bulk, Etmar, Schwab, Albrecht, Riecken, Kristoffer, Börnchen, Christian, Kiefmann, Rainer, Abraham, Valsamma, DeLisser, Horace M., Gemoll, Timo, Habermann, Jens K., Block, Andreas, Pantel, Klaus, Schumacher, Udo
Publicado 2022

Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo

por Genduso, Sandra, Freytag, Vera, Schetler, Daniela, Kirchner, Lennart, Schiecke, Alina, Maar, Hanna, Wicklein, Daniel, Gebauer, Florian, Bröker, Katharina, Stürken, Christine, Milde-Langosch, Karin, Oliveira-Ferrer, Leticia, Ricklefs, Franz L., Ewald, Florian, Wolters-Eisfeld, Gerrit, Riecken, Kristoffer, Unrau, Ludmilla, Krause, Linda, Bohnenberger, Hanibal, Offermann, Anne, Perner, Sven, Sebens, Susanne, Lamszus, Katrin, Diehl, Linda, Linder, Stefan, Jücker, Manfred, Schumacher, Udo, Lange, Tobias
Publicado 2023