TAL Effectors Specificity Stems from Negative Discrimination

por Wicky, Basile I. M., Stenta, Marco, Dal Peraro, Matteo
Publicado 2013

Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies

por Shammas, Sarah L., Crabtree, Michael D., Dahal, Liza, Wicky, Basile I. M., Clarke, Jane
Publicado 2016

Protein sequence design by conformational landscape optimization

por Norn, Christoffer, Wicky, Basile I. M., Juergens, David, Liu, Sirui, Kim, David, Tischer, Doug, Koepnick, Brian, Anishchenko, Ivan, Baker, David, Ovchinnikov, Sergey
Publicado 2021

Hallucination of closed repeat proteins containing central pockets

por An, Linna, Hicks, Derrick R., Zorine, Dmitri, Dauparas, Justas, Wicky, Basile I. M., Milles, Lukas F., Courbet, Alexis, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Carter, Lauren, Baker, David
Publicado 2023

De novo design of monomeric helical bundles for pH‐controlled membrane lysis

por Goldbach, Nicolas, Benna, Issa, Wicky, Basile I. M., Croft, Jacob T., Carter, Lauren, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Sankaran, Banumathi, Yang, Erin C., Lee, Kelly K., Baker, David
Publicado 2023

Stepwise design of pseudosymmetric protein hetero-oligomers

por Kibler, Ryan D., Lee, Sangmin, Kennedy, Madison A., Wicky, Basile I. M., Lai, Stella M., Kostelic, Marius M., Li, Xinting, Chow, Cameron M., Carter, Lauren, Wysocki, Vicki H., Stoddard, Barry L., Baker, David
Publicado 2023

Reconfigurable asymmetric protein assemblies through implicit negative design

por Sahtoe, Danny D., Praetorius, Florian, Courbet, Alexis, Hsia, Yang, Wicky, Basile I.M., Edman, Natasha I., Miller, Lauren M., Timmermans, Bart J. R., Decarreau, Justin, Morris, Hana M., Kang, Alex, Bera, Asim K., Baker, David
Publicado 2022

Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐x(L) and MCL‐1 through Noncanonical Structural Motifs

por Miles, Jennifer A., Hobor, Fruzsina, Trinh, Chi H., Taylor, James, Tiede, Christian, Rowell, Philip R., Jackson, Brian R., Nadat, Fatima A., Ramsahye, Pallavi, Kyle, Hannah F., Wicky, Basile I. M., Clarke, Jane, Tomlinson, Darren C., Wilson, Andrew J., Edwards, Thomas A.
Publicado 2020

Scaffolding protein functional sites using deep learning

por Wang, Jue, Lisanza, Sidney, Juergens, David, Tischer, Doug, Watson, Joseph L., Castro, Karla M., Ragotte, Robert, Saragovi, Amijai, Milles, Lukas F., Baek, Minkyung, Anishchenko, Ivan, Yang, Wei, Hicks, Derrick R., Expòsit, Marc, Schlichthaerle, Thomas, Chun, Jung-Ho, Dauparas, Justas, Bennett, Nathaniel, Wicky, Basile I. M., Muenks, Andrew, DiMaio, Frank, Correia, Bruno, Ovchinnikov, Sergey, Baker, David
Publicado 2022

Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants

por Zhang, Jason Z., Yeh, Hsien-Wei, Walls, Alexandra C., Wicky, Basile I. M., Sprouse, Kaitlin R., VanBlargan, Laura A., Treger, Rebecca, Quijano-Rubio, Alfredo, Pham, Minh N., Kraft, John C., Haydon, Ian C., Yang, Wei, DeWitt, Michelle, Bowen, John E., Chow, Cameron M., Carter, Lauren, Ravichandran, Rashmi, Wener, Mark H., Stewart, Lance, Veesler, David, Diamond, Michael S., Greninger, Alexander L., Koelle, David M., Baker, David
Publicado 2022

De novo design of protein structure and function with RFdiffusion

por Watson, Joseph L., Juergens, David, Bennett, Nathaniel R., Trippe, Brian L., Yim, Jason, Eisenach, Helen E., Ahern, Woody, Borst, Andrew J., Ragotte, Robert J., Milles, Lukas F., Wicky, Basile I. M., Hanikel, Nikita, Pellock, Samuel J., Courbet, Alexis, Sheffler, William, Wang, Jue, Venkatesh, Preetham, Sappington, Isaac, Torres, Susana Vázquez, Lauko, Anna, De Bortoli, Valentin, Mathieu, Emile, Ovchinnikov, Sergey, Barzilay, Regina, Jaakkola, Tommi S., DiMaio, Frank, Baek, Minkyung, Baker, David
Publicado 2023