From genetic discovery to future personalized health research

por Palotie, Aarno, Widén, Elisabeth, Ripatti, Samuli
Publicado 2013

Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes

por Tamlander, Max, Mars, Nina, Pirinen, Matti, Widén, Elisabeth, Ripatti, Samuli
Publicado 2022

Association of LIN28B with Adult Adiposity-Related Traits in Females

por Leinonen, Jaakko T., Surakka, Ida, Havulinna, Aki S., Kettunen, Johannes, Luoto, Riitta, Salomaa, Veikko, Widén, Elisabeth
Publicado 2012

LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels

por Leinonen, Jaakko T., Chen, Yu-Chia, Pennonen, Jana, Lehtonen, Leevi, Junna, Nella, Tukiainen, Taru, Panula, Pertti, Widén, Elisabeth
Publicado 2019

Systematic comparison of family history and polygenic risk across 24 common diseases

por Mars, Nina, Lindbohm, Joni V., della Briotta Parolo, Pietro, Widén, Elisabeth, Kaprio, Jaakko, Palotie, Aarno, Ripatti, Samuli
Publicado 2022

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

por Ottensmann, Linda, Tabassum, Rubina, Ruotsalainen, Sanni E., Gerl, Mathias J., Klose, Christian, Widén, Elisabeth, Simons, Kai, Ripatti, Samuli, Pirinen, Matti
Publicado 2023

Lipidome‐ and Genome‐Wide Study to Understand Sex Differences in Circulatory Lipids

por Tabassum, Rubina, Ruotsalainen, Sanni, Ottensmann, Linda, Gerl, Mathias J., Klose, Christian, Tukiainen, Taru, Pirinen, Matti, Simons, Kai, Widén, Elisabeth, Ripatti, Samuli
Publicado 2022

Genealogy and clinical course of catecholaminergic polymorphic ventricular tachycardia caused by the ryanodine receptor type 2 P2328S mutation

por Koponen, Mikael, Marjamaa, Annukka, Tuiskula, Annukka M., Viitasalo, Matti, Nallinmaa-Luoto, Terhi, Leinonen, Jaakko T., Widen, Elisabeth, Toivonen, Lauri, Kontula, Kimmo, Swan, Heikki
Publicado 2020

Targeted Resequencing of the Pericentromere of Chromosome 2 Linked to Constitutional Delay of Growth and Puberty

por Cousminer, Diana L., Leinonen, Jaakko T., Sarin, Antti-Pekka, Chheda, Himanshu, Surakka, Ida, Wehkalampi, Karoliina, Ellonen, Pekka, Ripatti, Samuli, Dunkel, Leo, Palotie, Aarno, Widén, Elisabeth
Publicado 2015

The role of polygenic risk and susceptibility genes in breast cancer over the course of life

por Mars, Nina, Widén, Elisabeth, Kerminen, Sini, Meretoja, Tuomo, Pirinen, Matti, della Briotta Parolo, Pietro, Palta, Priit, Palotie, Aarno, Kaprio, Jaakko, Joensuu, Heikki, Daly, Mark, Ripatti, Samuli
Publicado 2020

Pubertal Timing and Growth Influences Cardiometabolic Risk Factors in Adult Males and Females

por Widén, Elisabeth, Silventoinen, Karri, Sovio, Ulla, Ripatti, Samuli, Cousminer, Diana L., Hartikainen, Anna-Liisa, Laitinen, Jaana, Pouta, Anneli, Kaprio, Jaakko, Järvelin, Marjo-Riitta, Peltonen, Leena, Palotie, Aarno
Publicado 2012

Effectiveness and feasibility of cardiovascular disease personalized prevention on high polygenic risk score subjects: a randomized controlled pilot study

por Viigimaa, Margus, Jürisson, Mikk, Pisarev, Heti, Kalda, Ruth, Alavere, Helene, Irs, Alar, Saar, Aet, Fischer, Krista, Läll, Kristi, Kruuv-Käo, Krista, Mars, Nina, Widen, Elisabeth, Ripatti, Samuli, Metspalu, Andres
Publicado 2022

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

por Ripatti, Pietari, Rämö, Joel T., Mars, Nina J., Fu, Yu, Lin, Jake, Söderlund, Sanni, Benner, Christian, Surakka, Ida, Kiiskinen, Tuomo, Havulinna, Aki S., Palta, Priit, Freimer, Nelson B., Widén, Elisabeth, Salomaa, Veikko, Tukiainen, Taru, Pirinen, Matti, Palotie, Aarno, Taskinen, Marja-Riitta, Ripatti, Samuli
Publicado 2020

Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis

por Ruotsalainen, Sanni E., Surakka, Ida, Mars, Nina, Karjalainen, Juha, Kurki, Mitja, Kanai, Masahiro, Krebs, Kristi, Graham, Sarah, Mishra, Pashupati P., Mishra, Binisha H., Sinisalo, Juha, Palta, Priit, Lehtimäki, Terho, Raitakari, Olli, Milani, Lili, Okada, Yukinori, Palotie, Aarno, Widen, Elisabeth, Daly, Mark J., Ripatti, Samuli
Publicado 2022

Intracranial Aneurysm Risk Locus 5q23.2 Is Associated with Elevated Systolic Blood Pressure

por Gaál, Emília Ilona, Salo, Perttu, Kristiansson, Kati, Rehnström, Karola, Kettunen, Johannes, Sarin, Antti-Pekka, Niemelä, Mika, Jula, Antti, Raitakari, Olli T., Lehtimäki, Terho, Eriksson, Johan G., Widen, Elisabeth, Günel, Murat, Kurki, Mitja, von und zu Fraunberg, Mikael, Jääskeläinen, Juha E., Hernesniemi, Juha, Järvelin, Marjo-Riitta, Pouta, Anneli, Newton-Cheh, Christopher, Salomaa, Veikko, Palotie, Aarno, Perola, Markus
Publicado 2012

Combined Genome Scans for Body Stature in 6,602 European Twins: Evidence for Common Caucasian Loci

por Perola, Markus, Sammalisto, Sampo, Hiekkalinna, Tero, Martin, Nick G, Visscher, Peter M, Montgomery, Grant W, Benyamin, Beben, Harris, Jennifer R, Boomsma, Dorret, Willemsen, Gonneke, Hottenga, Jouke-Jan, Christensen, Kaare, Kyvik, Kirsten Ohm, Sørensen, Thorkild I. A, Pedersen, Nancy L, Magnusson, Patrik K. E, Spector, Tim D, Widen, Elisabeth, Silventoinen, Karri, Kaprio, Jaakko, Palotie, Aarno, Peltonen, Leena
Publicado 2007

Genetic Determinants of Height Growth Assessed Longitudinally from Infancy to Adulthood in the Northern Finland Birth Cohort 1966

por Sovio, Ulla, Bennett, Amanda J., Millwood, Iona Y., Molitor, John, O'Reilly, Paul F., Timpson, Nicholas J., Kaakinen, Marika, Laitinen, Jaana, Haukka, Jari, Pillas, Demetris, Tzoulaki, Ioanna, Molitor, Jassy, Hoggart, Clive, Coin, Lachlan J. M., Whittaker, John, Pouta, Anneli, Hartikainen, Anna-Liisa, Freimer, Nelson B., Widen, Elisabeth, Peltonen, Leena, Elliott, Paul, McCarthy, Mark I., Jarvelin, Marjo-Riitta
Publicado 2009

Identification of MAMDC1 as a Candidate Susceptibility Gene for Systemic Lupus Erythematosus (SLE)

por Hellquist, Anna, Zucchelli, Marco, Lindgren, Cecilia M., Saarialho-Kere, Ulpu, Järvinen, Tiina M., Koskenmies, Sari, Julkunen, Heikki, Onkamo, Päivi, Skoog, Tiina, Panelius, Jaana, Räisänen-Sokolowski, Anne, Hasan, Taina, Widen, Elisabeth, Gunnarson, Iva, Svenungsson, Elisabet, Padyukov, Leonid, Assadi, Ghazaleh, Berglind, Linda, Mäkelä, Ville-Veikko, Kivinen, Katja, Wong, Andrew, Cunningham Graham, Deborah S., Vyse, Timothy J., D'Amato, Mauro, Kere, Juha
Publicado 2009

Molecular Genetic Evidence for Genetic Overlap between General Cognitive Ability and Risk for Schizophrenia: A Report from the Cognitive Genomics Consortium (COGENT)

por Lencz, Todd, Knowles, Emma, Davies, Gail, Guha, Saurav, Liewald, David C, Starr, John M, Djurovic, Srdjan, Melle, Ingrid, Sundet, Kjetil, Christoforou, Andrea, Reinvang, Ivar, Mukherjee, Semanti, Lundervold, Astri, Steen, Vidar M., John, Majnu, Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G, Giegling, Ina, Konte, Bettina, Ikeda, Masashi, Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E., Payton, Antony, Ollier, William, Horan, Mike, Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Pendleton, Neil, Iwata, Nakao, Darvasi, Ariel, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Hellard, Stephanie Le, Keller, Matthew C., Andreassen, Ole A., Deary, Ian J, Glahn, David C., Malhotra, Anil K.
Publicado 2013

Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA

por Ramasamy, Adaikalavan, Kuokkanen, Mikko, Vedantam, Sailaja, Gajdos, Zofia K., Couto Alves, Alexessander, Lyon, Helen N., Ferreira, Manuel A. R., Strachan, David P., Zhao, Jing Hua, Abramson, Michael J., Brown, Matthew A., Coin, Lachlan, Dharmage, Shyamali C., Duffy, David L., Haahtela, Tari, Heath, Andrew C., Janson, Christer, Kähönen, Mika, Khaw, Kay-Tee, Laitinen, Jaana, Le Souef, Peter, Lehtimäki, Terho, Madden, Pamela A. F., Marks, Guy B., Martin, Nicholas G., Matheson, Melanie C., Palmer, Cameron D., Palotie, Aarno, Pouta, Anneli, Robertson, Colin F., Viikari, Jorma, Widen, Elisabeth, Wjst, Matthias, Jarvis, Deborah L., Montgomery, Grant W., Thompson, Philip J., Wareham, Nick, Eriksson, Johan, Jousilahti, Pekka, Laitinen, Tarja, Pekkanen, Juha, Raitakari, Olli T., O'Connor, George T., Salomaa, Veikko, Jarvelin, Marjo-Riitta, Hirschhorn, Joel N.
Publicado 2012