Circulating Tumor Cells in Metastatic Breast Cancer: From Genome Instability to Metastasis

por Ivanova, Ekaterina, Ward, Ambber, Wiegmans, Adrian P., Richard, Derek John
Publicado 2020

RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

por Wiegmans, Adrian P., Miranda, Mariska, Wen, Shu Wen, Al-Ejeh, Fares, Möller, Andreas
Publicado 2016

Current challenges in metastasis research and future innovation for clinical translation

por Parker, Amelia L., Benguigui, Madeleine, Fornetti, Jaime, Goddard, Erica, Lucotti, Serena, Insua-Rodríguez, Jacob, Wiegmans, Adrian P.
Publicado 2022

Optimized exosome isolation protocol for cell culture supernatant and human plasma

por Lobb, Richard J., Becker, Melanie, Wen Wen, Shu, Wong, Christina S. F., Wiegmans, Adrian P., Leimgruber, Antoine, Möller, Andreas
Publicado 2015

High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations

por Johnston, Rebecca L., Wockner, Leesa, McCart Reed, Amy E., Wiegmans, Adrian, Chenevix-Trench, Georgia, Khanna, Kum Kum, Lakhani, Sunil R., Smart, Chanel E.
Publicado 2016

Breast Cancer-Derived Exosomes Alter Macrophage Polarization via gp130/STAT3 Signaling

por Ham, Sunyoung, Lima, Luize G., Chai, Edna Pei Zhi, Muller, Alexandra, Lobb, Richard J., Krumeich, Sophie, Wen, Shu Wen, Wiegmans, Adrian P., Möller, Andreas
Publicado 2018

EGFR and Prion protein promote signaling via FOXO3a‐KLF5 resulting in clinical resistance to platinum agents in colorectal cancer

por Atkinson, Caroline J., Kawamata, Futoshi, Liu, Cheng, Ham, Sunyoung, Győrffy, Balázs, Munn, Alan L., Wei, Ming Q., Möller, Andreas, Whitehall, Vicki, Wiegmans, Adrian P.
Publicado 2019

Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen

por Bhatia, Sugandha, Blick, Tony, Pinto, Cletus, Waltham, Mark, Monkman, James, Ivanova, Ekaterina, Pollock, Pamela M., Nagaraj, Shivashankar H., Wiegmans, Adrian P., Haviv, Izhak, Simpson, Kaylene J., Thompson, Erik W.
Publicado 2020

Rad51 supports triple negative breast cancer metastasis

por Wiegmans, Adrian P, Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J, Silva, Leonard Da, Bolderson, Emma, Chenevix-Trench, Georgia, Anderson, Robin, Simpson, Peter T, Lakhani, Sunil R, Khanna, Kum Kum
Publicado 2014

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

por Al-Ejeh, Fares, Miranda, Mariska, Shi, Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R., Khanna, Kum Kum
Publicado 2014

Genome instability and pressure on non-homologous end joining drives chemotherapy resistance via a DNA repair crisis switch in triple negative breast cancer

por Wiegmans, Adrian P, Ward, Ambber, Ivanova, Ekaterina, Duijf, Pascal H G, Adams, Mark N, Najib, Idris Mohd, Van Oosterhout, Romy, Sadowski, Martin C, Kelly, Greg, Morrical, Scott W, O’Byrne, Ken, Lee, Jason S, Richard, Derek J
Publicado 2021

Correction to ‘Genome instability and pressure on non-homologous end joining drives chemotherapy resistance via a DNA repair crisis switch in triple negative breast cancer’

por Wiegmans, Adrian P, Ward, Ambber, Ivanova, Ekaterina, Duijf, Pascal H G, Adams, Mark N, Najib, Idris Mohd, Van Oosterhout, Romy, Sadowski, Martin C, Kelly, Greg, Morrical, Scott W, O’Byrne, Ken, Lee, Jason S, Richard, Derek J
Publicado 2021

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefi...

por Bessette, Darrell C., Tilch, Erik, Seidens, Tatjana, Quinn, Michael C. J., Wiegmans, Adrian P., Shi, Wei, Cocciardi, Sibylle, McCart-Reed, Amy, Saunus, Jodi M., Simpson, Peter T., Grimmond, Sean M., Lakhani, Sunil R., Khanna, Kum Kum, Waddell, Nic, Al-Ejeh, Fares, Chenevix-Trench, Georgia
Publicado 2015

Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore

por Lim, Yi Chieh, Ensbey, Kathleen S, Offenhäuser, Carolin, D’souza, Rochelle C J, Cullen, Jason K, Stringer, Brett W, Quek, Hazel, Bruce, Zara C, Kijas, Amanda, Cianfanelli, Valentina, Mahboubi, Bijan, Smith, Fiona, Jeffree, Rosalind L, Wiesmüeller, Lisa, Wiegmans, Adrian P, Bain, Amanda, Lombard, Fanny J, Roberts, Tara L, Khanna, Kum Kum, Lavin, Martin F, Kim, Baek, Hamerlik, Petra, Johns, Terrance G, Coster, Mark J, Boyd, Andrew W, Day, Bryan W
Publicado 2020