A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells

por Xu, Yunjian, Schwede, Frank, Wienk, Hans, Tengholm, Anders, Rehmann, Holger
Publicado 2019

DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface

por Corbeski, Ivan, Dolinar, Klemen, Wienk, Hans, Boelens, Rolf, van Ingen, Hugo
Publicado 2018

The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition

por Wienk, Hans, Slootweg, Jack C., Speerstra, Sietske, Kaptein, Robert, Boelens, Rolf, Folkers, Gert E.
Publicado 2013

Disordered Peptides Looking for Their Native Environment: Structural Basis of CB1 Endocannabinoid Receptor Binding to Pepcans

por Emendato, Alessandro, Guerrini, Remo, Marzola, Erika, Wienk, Hans, Boelens, Rolf, Leone, Serena, Picone, Delia
Publicado 2018

Identification of a diagnostic structural motif reveals a new reaction intermediate and condensation pathway in kraft lignin formation

por Lancefield, Christopher S., Wienk, Hans L. J., Boelens, Rolf, Weckhuysen, Bert M., Bruijnincx, Pieter C. A.
Publicado 2018

New Insights Into the Polar Lipid Composition of Extremely Halo(alkali)philic Euryarchaea From Hypersaline Lakes

por Bale, Nicole J., Sorokin, Dimitry Y., Hopmans, Ellen C., Koenen, Michel, Rijpstra, W. Irene C., Villanueva, Laura, Wienk, Hans, Sinninghe Damsté, Jaap S.
Publicado 2019

Diubiquitin-Based NMR Analysis: Interactions Between Lys6-Linked diUb and UBA Domain of UBXN1

por Shahul Hameed, Dharjath, van Tilburg, Gabrielle B. A., Merkx, Remco, Flierman, Dennis, Wienk, Hans, El Oualid, Farid, Hofmann, Kay, Boelens, Rolf, Ovaa, Huib
Publicado 2020

Lysine and novel hydroxylysine lipids in soil bacteria: amino acid membrane lipid response to temperature and pH in Pseudopedobacter saltans

por Moore, Eli K., Hopmans, Ellen C., Rijpstra, W. Irene C., Sánchez-Andrea, Irene, Villanueva, Laura, Wienk, Hans, Schoutsen, Frans, Stams, Alfons J. M., Sinninghe Damsté, Jaap S.
Publicado 2015

Lipids Are the Preferred Substrate of the Protist Naegleria gruberi, Relative of a Human Brain Pathogen

por Bexkens, Michiel L., Zimorski, Verena, Sarink, Maarten J., Wienk, Hans, Brouwers, Jos F., De Jonckheere, Johan F., Martin, William F., Opperdoes, Fred R., van Hellemond, Jaap J., Tielens, Aloysius G.M.
Publicado 2018

Structure-Guided Design of Selective Epac1 and Epac2 Agonists

por Schwede, Frank, Bertinetti, Daniela, Langerijs, Carianne N., Hadders, Michael A., Wienk, Hans, Ellenbroek, Johanne H., de Koning, Eelco J. P., Bos, Johannes L., Herberg, Friedrich W., Genieser, Hans-Gottfried, Janssen, Richard A. J., Rehmann, Holger
Publicado 2015

NMR Structure of the FIV gp36 C-terminal Heptad Repeat and Membrane-Proximal External Region

por Grimaldi, Manuela, Buonocore, Michela, Scrima, Mario, Stillitano, Ilaria, D’Errico, Gerardino, Santoro, Angelo, Amodio, Giuseppina, Eletto, Daniela, Gloria, Antonio, Russo, Teresa, Moltedo, Ornella, Remondelli, Paolo, Tosco, Alessandra, Wienk, Hans L. J, D’Ursi, Anna Maria
Publicado 2020

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF

por Corbeski, Ivan, Guo, Xiaohu, Eckhardt, Bruna V., Fasci, Domenico, Wiegant, Wouter, Graewert, Melissa A., Vreeken, Kees, Wienk, Hans, Svergun, Dmitri I., Heck, Albert J. R., van Attikum, Haico, Boelens, Rolf, Sixma, Titia K., Mattiroli, Francesca, van Ingen, Hugo
Publicado 2022