Acalabrutinib: A Selective Bruton Tyrosine Kinase Inhibitor for the Treatment of B-Cell Malignancies

por Abbas, Hussein A., Wierda, William G.
Publicado 2021

The Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View

por Tambaro, Francesco Paolo, De Novellis, Danilo, Wierda, William G
Publicado 2021

Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL)

por Al-Kali, Aref, Wierda, William, Keating, Michael, O’Brien, Susan
Publicado 2010

Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia: Response to obinutuzumab

por Jain, Punit, Kanagal-Shamanna, Rashmi, Wierda, William, Ferrajoli, Alessandra, Keating, Michael, Jain, Nitin
Publicado 2016

Regulation of Mcl-1 Expression in Context to Bone Marrow Stromal Microenvironment in Chronic Lymphocytic Leukemia()

por Balakrishnan, Kumudha, Burger, Jan A., Fu, Min, Doifode, Tejaswini, Wierda, William G., Gandhi, Varsha
Publicado 2014

Reactivation of Smac-mediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic

por Balakrishnan, Kumudha, Fu, Min, Onida, Francesco, Wierda, William G., Keating, Michael J., Gandhi, Varsha
Publicado 2016

Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells

por Modi, Prexy, Balakrishnan, Kumudha, Yang, Qingshan, Wierda, William G., Keating, Michael J., Gandhi, Varsha
Publicado 2017

P637: TIME-LIMITED TREATMENT WITH ACALABRUTINIB PLUS OBINUTUZUMAB IN TREATMENT-NAÏVE CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS: EARLY RESULTS OF AN ONGOING PHASE 2 TRIAL

por Burger, Jan, Kim, Ekaterina, Sivina, Mariela, Issa, Ghayas, Thompson, Philip, G. Wierda, William, Ferrajoli, Alessandra
Publicado 2023

Prognostication of DNA Damage Response Protein Expression Patterns in Chronic Lymphocytic Leukemia

por Griffen, Ti’ara L., Hoff, Fieke W., Qiu, Yihua, Burger, Jan, Wierda, William, Kornblau, Steven M.
Publicado 2023

The TKI Era in Chronic Leukemias

por De Novellis, Danilo, Cacace, Fabiana, Caprioli, Valeria, Wierda, William G., Mahadeo, Kris M., Tambaro, Francesco Paolo
Publicado 2021

Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia

por Yi, Xue, Jain, Nitin, Iles, LaKesla R., Ayres, Mary L., Wierda, William G., Gandhi, Varsha
Publicado 2022

PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells

por Cervantes-Gomez, Fabiola, Stellrecht, Christine M., Ayres, Mary L., Keating, Michael J., Wierda, William G., Gandhi, Varsha
Publicado 2019

2211. Impact of Early Fiberoptic Bronchoscopy on Microbiological Diagnostic Rate and Clinical Outcomes of Pneumonia in Acute Leukemia Patients

por Sakurai, Aki, Bala-Hampton, Justin E, Mulanovich, Victor E, Wierda, William G, Cortes, Jorge E, Adachi, Javier
Publicado 2019

Vecabrutinib inhibits B-cell receptor signal transduction in chronic lymphocytic leukemia cell types with wild-type or mutant Bruton tyrosine kinase

por Aslan, Burcu, Hubner, Stefan Edward, Fox, Judith A., Taverna, Pietro, Wierda, William G., Kornblau, Steven M., Gandhi, Varsha
Publicado 2021

Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells

por Chen, Rong, Chen, Yuling, Xiong, Ping, Zheleva, Daniella, Blake, David, Keating, Michael J., Wierda, William G., Plunkett, William
Publicado 2022

Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells

por Vangapandu, Hima V., Alston, Brandon, Morse, Joshua, Ayres, Mary L., Wierda, William G., Keating, Michael J., Marszalek, Joseph R., Gandhi, Varsha
Publicado 2018

1719. Incidence and Characterization of Invasive Fungal Infections (IFIs) in Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Ibrutinib (IBR)

por Frei, Michael, Aitken, Samuel L, Aitken, Samuel L, Jain, Nitin, Thompson, Philip, Wierda, William G, Kontoyiannis, Dimitrios P, DiPippo, Adam
Publicado 2019

Complete remission in refractory acute lymphoblastic leukemia using blinatumomab after failure of response to CD‐19 chimeric antigen receptor T‐cell therapy

por Tambaro, Francesco Paolo, Khazal, Sajad, Nunez, Cesar, Ragoonanan, Dristhi, Tewari, Priti, Petropoulos, Demetrios, Kebriaei, Partow, Wierda, William George, Mahadeo, Kris Michael
Publicado 2020

Monitoring and Managing BTK Inhibitor Treatment-Related Adverse Events in Clinical Practice

por O’Brien, Susan M., Brown, Jennifer R., Byrd, John C., Furman, Richard R., Ghia, Paolo, Sharman, Jeff P., Wierda, William G.
Publicado 2021

The Stromal Microenvironment Modulates Mitochondrial Oxidative Phosphorylation in Chronic Lymphocytic Leukemia Cells()()

por Vangapandu, Hima V., Ayres, Mary L., Bristow, Christopher A., Wierda, William G., Keating, Michael J., Balakrishnan, Kumudha, Stellrecht, Christine M., Gandhi, Varsha
Publicado 2017