Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes

por Wierer, Michael, Mann, Matthias
Publicado 2016

Anti-inflammatory functions of the glucocorticoid receptor require DNA binding

por Escoter-Torres, Laura, Greulich, Franziska, Quagliarini, Fabiana, Wierer, Michael, Uhlenhaut, Nina Henriette
Publicado 2020

The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers

por Greulich, Franziska, Wierer, Michael, Mechtidou, Aikaterini, Gonzalez-Garcia, Omar, Uhlenhaut, N. Henriette
Publicado 2021

A Single Glycine-Alanine Exchange Directs Ligand Specificity of the Elephant Progestin Receptor

por Wierer, Michael, Schrey, Anna K., Kühne, Ronald, Ulbrich, Susanne E., Meyer, Heinrich H. D.
Publicado 2012

Identification of permissive amber suppression sites for efficient non-canonical amino acid incorporation in mammalian cells

por Bartoschek, Michael D, Ugur, Enes, Nguyen, Tuan‐Anh, Rodschinka, Geraldine, Wierer, Michael, Lang, Kathrin, Bultmann, Sebastian
Publicado 2021

Independent control of COVID-19 vaccines by EU Official Control Authority Batch Release: challenges, strengths and successes

por Milne, Catherine, Wagner, Ralf, Cano, François, Bruysters, Martijn, Waeterloos, Geneviève, Pullirsch, Dieter, Wierer, Michael, Mallet, Laurent
Publicado 2023

E47 modulates hepatic glucocorticoid action

por Hemmer, M. Charlotte, Wierer, Michael, Schachtrup, Kristina, Downes, Michael, Hübner, Norbert, Evans, Ronald M., Uhlenhaut, N. Henriette
Publicado 2019

Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions

por Reusswig, Karl-Uwe, Bittmann, Julia, Peritore, Martina, Courtes, Mathilde, Pardo, Benjamin, Wierer, Michael, Mann, Matthias, Pfander, Boris
Publicado 2022

Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry

por Reim, Alexander, Ackermann, Roland, Font-Mateu, Jofre, Kammel, Robert, Beato, Miguel, Nolte, Stefan, Mann, Matthias, Russmann, Christoph, Wierer, Michael
Publicado 2020

Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components

por Ugur, Enes, de la Porte, Alexandra, Qin, Weihua, Bultmann, Sebastian, Ivanova, Alina, Drukker, Micha, Mann, Matthias, Wierer, Michael, Leonhardt, Heinrich
Publicado 2023

Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms

por Scacchetti, Alessandro, Schauer, Tamas, Reim, Alexander, Apostolou, Zivkos, Campos Sparr, Aline, Krause, Silke, Heun, Patrick, Wierer, Michael, Becker, Peter B
Publicado 2020

Heat shock induces premature transcript termination and reconfigures the human transcriptome

por Cugusi, Simona, Mitter, Richard, Kelly, Gavin P., Walker, Jane, Han, Zhong, Pisano, Paola, Wierer, Michael, Stewart, Aengus, Svejstrup, Jesper Q.
Publicado 2022

Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner

por Saenz, Carmen, Fang, Qing, Gnanasekaran, Thiyagarajan, Trammell, Samuel Addison Jack, Buijink, Jesse Arnold, Pisano, Paola, Wierer, Michael, Moens, Frédéric, Lengger, Bettina, Brejnrod, Asker, Arumugam, Manimozhiyan
Publicado 2023

Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end‐stage cancer patient

por Doll, Sophia, Kriegmair, Maximilian C., Santos, Alberto, Wierer, Michael, Coscia, Fabian, Neil, Helen Michele, Porubsky, Stefan, Geyer, Philipp E., Mund, Andreas, Nuhn, Philipp, Mann, Matthias
Publicado 2018

Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency

por Qin, Weihua, Ugur, Enes, Mulholland, Christopher B, Bultmann, Sebastian, Solovei, Irina, Modic, Miha, Smets, Martha, Wierer, Michael, Forné, Ignasi, Imhof, Axel, Cardoso, M Cristina, Leonhardt, Heinrich
Publicado 2021

Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression

por Wierer, Michael, Prestel, Matthias, Schiller, Herbert B., Yan, Guangyao, Schaab, Christoph, Azghandi, Sepiede, Werner, Julia, Kessler, Thorsten, Malik, Rainer, Murgia, Marta, Aherrahrou, Zouhair, Schunkert, Heribert, Dichgans, Martin, Mann, Matthias
Publicado 2018

Kreuth V initiative: European consensus proposals for treatment of hemophilia using standard products, extended half-life coagulation factor concentrates and non-replacement therap...

por Peyvandi, Flora, Berger, Karin, Seitz, Rainer, Hilger, Anneliese, Hecquet, Marie-Laure, Wierer, Michael, Buchheit, Karl-Heinz, O’Mahony, Brian, Bok, Amanda, Makris, Mike, Mansmann, Ulrich, Schramm, Wolfgang, Mannucci, Pier Mannuccio
Publicado 2020

A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy

por Wierer, Michael, Werner, Julia, Wobst, Jana, Kastrati, Adnan, Cepele, Ganildo, Aherrahrou, Redouane, Sager, Hendrik B, Erdmann, Jeanette, Dichgans, Martin, Flockerzi, Veit, Civelek, Mete, Dietrich, Alexander, Mann, Matthias, Schunkert, Heribert, Kessler, Thorsten
Publicado 2021

TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation

por Stolz, Paul, Mantero, Angelo Salazar, Tvardovskiy, Andrey, Ugur, Enes, Wange, Lucas E, Mulholland, Christopher B, Cheng, Yuying, Wierer, Michael, Enard, Wolfgang, Schneider, Robert, Bartke, Till, Leonhardt, Heinrich, Elsässer, Simon J, Bultmann, Sebastian
Publicado 2022

Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

por Hoefig, Kai P., Reim, Alexander, Gallus, Christian, Wong, Elaine H., Behrens, Gesine, Conrad, Christine, Xu, Meng, Kifinger, Lisa, Ito-Kureha, Taku, Defourny, Kyra A. Y., Geerlof, Arie, Mautner, Josef, Hauck, Stefanie M., Baumjohann, Dirk, Feederle, Regina, Mann, Matthias, Wierer, Michael, Glasmacher, Elke, Heissmeyer, Vigo
Publicado 2021