Integrative Analysis of Cancer-Related Signaling Pathways

por Kessler, Thomas, Hache, Hendrik, Wierling, Christoph
Publicado 2013

GeNGe: systematic generation of gene regulatory networks

por Hache, Hendrik, Wierling, Christoph, Lehrach, Hans, Herwig, Ralf
Publicado 2009

ConsensusPathDB—a database for integrating human functional interaction networks

por Kamburov, Atanas, Wierling, Christoph, Lehrach, Hans, Herwig, Ralf
Publicado 2009

Modeling of miRNA and Drug Action in the EGFR Signaling Pathway

por Li, Jian, Pandey, Vikash, Kessler, Thomas, Lehrach, Hans, Wierling, Christoph
Publicado 2012

ConsensusPathDB: toward a more complete picture of cell biology

por Kamburov, Atanas, Pentchev, Konstantin, Galicka, Hanna, Wierling, Christoph, Lehrach, Hans, Herwig, Ralf
Publicado 2011

Predictive Modeling of Drug Treatment in the Area of Personalized Medicine

por Ogilvie, Lesley A., Wierling, Christoph, Kessler, Thomas, Lehrach, Hans, Lange, Bodo M. H.
Publicado 2015

Models of Models: A Translational Route for Cancer Treatment and Drug Development

por Ogilvie, Lesley A., Kovachev, Aleksandra, Wierling, Christoph, Lange, Bodo M. H., Lehrach, Hans
Publicado 2017

Monte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network

por Kühn, Clemens, Wierling, Christoph, Kühn, Alexander, Klipp, Edda, Panopoulou, Georgia, Lehrach, Hans, Poustka, Albert J
Publicado 2009

Simulation of DNA array hybridization experiments and evaluation of critical parameters during subsequent image and data analysis

por Wierling, Christoph K, Steinfath, Matthias, Elge, Thorsten, Schulze-Kremer, Steffen, Aanstad, Pia, Clark, Matthew, Lehrach, Hans, Herwig, Ralf
Publicado 2002

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors

por Stehr, Henning, Jang, Seon-Hi J, Duarte, José M, Wierling, Christoph, Lehrach, Hans, Lappe, Michael, Lange, Bodo MH
Publicado 2011

Mini-batch optimization enables training of ODE models on large-scale datasets

por Stapor, Paul, Schmiester, Leonard, Wierling, Christoph, Merkt, Simon, Pathirana, Dilan, Lange, Bodo M. H., Weindl, Daniel, Hasenauer, Jan
Publicado 2022

An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts

por Tantiwong, Chukiat, Dunster, Joanne L., Cavill, Rachel, Tomlinson, Michael G., Wierling, Christoph, Heemskerk, Johan W. M., Gibbins, Jonathan M.
Publicado 2023

Synergism between Hedgehog-GLI and EGFR Signaling in Hedgehog-Responsive Human Medulloblastoma Cells Induces Downregulation of Canonical Hedgehog-Target Genes and Stabilized Expres...

por Götschel, Frank, Berg, Daniela, Gruber, Wolfgang, Bender, Christian, Eberl, Markus, Friedel, Myriam, Sonntag, Johanna, Rüngeler, Elena, Hache, Hendrik, Wierling, Christoph, Nietfeld, Wilfried, Lehrach, Hans, Frischauf, Annemarie, Schwartz-Albiez, Reinhard, Aberger, Fritz, Korf, Ulrike
Publicado 2013

Comparative Analysis and Modeling of the Severity of Steatohepatitis in DDC-Treated Mouse Strains

por Pandey, Vikash, Sultan, Marc, Kashofer, Karl, Ralser, Meryem, Amstislavskiy, Vyacheslav, Starmann, Julia, Osprian, Ingrid, Grimm, Christina, Hache, Hendrik, Yaspo, Marie-Laure, Sültmann, Holger, Trauner, Michael, Denk, Helmut, Zatloukal, Kurt, Lehrach, Hans, Wierling, Christoph
Publicado 2014

A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells

por Jozefczuk, Justyna, Kashofer, Karl, Ummanni, Ramesh, Henjes, Frauke, Rehman, Samrina, Geenen, Suzanne, Wruck, Wasco, Regenbrecht, Christian, Daskalaki, Andriani, Wierling, Christoph, Turano, Paola, Bertini, Ivano, Korf, Ulrike, Zatloukal, Kurt, Westerhoff, Hans V., Lehrach, Hans, Adjaye, James
Publicado 2012

Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes

por Wruck, Wasco, Kashofer, Karl, Rehman, Samrina, Daskalaki, Andriani, Berg, Daniela, Gralka, Ewa, Jozefczuk, Justyna, Drews, Katharina, Pandey, Vikash, Regenbrecht, Christian, Wierling, Christoph, Turano, Paola, Korf, Ulrike, Zatloukal, Kurt, Lehrach, Hans, Westerhoff, Hans V., Adjaye, James
Publicado 2015

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

por Eberl, Markus, Klingler, Stefan, Mangelberger, Doris, Loipetzberger, Andrea, Damhofer, Helene, Zoidl, Kerstin, Schnidar, Harald, Hache, Hendrik, Bauer, Hans-Christian, Solca, Flavio, Hauser-Kronberger, Cornelia, Ermilov, Alexandre N, Verhaegen, Monique E, Bichakjian, Christopher K, Dlugosz, Andrzej A, Nietfeld, Wilfried, Sibilia, Maria, Lehrach, Hans, Wierling, Christoph, Aberger, Fritz
Publicado 2012

High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications

por Röhr, Christina, Kerick, Martin, Fischer, Axel, Kühn, Alexander, Kashofer, Karl, Timmermann, Bernd, Daskalaki, Andriani, Meinel, Thomas, Drichel, Dmitriy, Börno, Stefan T., Nowka, Anja, Krobitsch, Sylvia, McHardy, Alice C., Kratsch, Christina, Becker, Tim, Wunderlich, Andrea, Barmeyer, Christian, Viertler, Christian, Zatloukal, Kurt, Wierling, Christoph, Lehrach, Hans, Schweiger, Michal R.
Publicado 2013

Synergistic cross‐talk of hedgehog and interleukin‐6 signaling drives growth of basal cell carcinoma

por Sternberg, Christina, Gruber, Wolfgang, Eberl, Markus, Tesanovic, Suzana, Stadler, Manuela, Elmer, Dominik P., Schlederer, Michaela, Grund, Sandra, Roos, Simone, Wolff, Florian, Kaur, Supreet, Mangelberger, Doris, Lehrach, Hans, Hache, Hendrik, Wierling, Christoph, Laimer, Josef, Lackner, Peter, Wiederstein, Markus, Kasper, Maria, Risch, Angela, Petzelbauer, Peter, Moriggl, Richard, Kenner, Lukas, Aberger, Fritz
Publicado 2018

Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins

por Maqsood, Zahra, Clark, Joanne C., Martin, Eleyna M., Cheung, Yam Fung Hilaire, Morán, Luis A., Watson, Sean E. T., Pike, Jeremy A., Di, Ying, Poulter, Natalie S., Slater, Alexandre, Lange, Bodo M. H., Nieswandt, Bernhard, Eble, Johannes A., Tomlinson, Mike G., Owen, Dylan M., Stegner, David, Bridge, Lloyd J., Wierling, Christoph, Watson, Steve P.
Publicado 2022