The Neutrophil: The Underdog That Packs a Punch in the Fight against Cancer

por Ustyanovska Avtenyuk, Natasha, Visser, Nienke, Bremer, Edwin, Wiersma, Valerie R.
Publicado 2020

The multifaceted role of autophagy in cancer and the microenvironment

por Folkerts, Hendrik, Hilgendorf, Susan, Vellenga, Edo, Bremer, Edwin, Wiersma, Valerie R.
Publicado 2018

Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity

por Wiersma, Valerie R., Michalak, Marek, Abdullah, Trefa M., Bremer, Edwin, Eggleton, Paul
Publicado 2015

The Ever-Expanding Immunomodulatory Role of Calreticulin in Cancer Immunity

por de Bruyn, Marco, Wiersma, Valerie R., Helfrich, Wijnand, Eggleton, Paul, Bremer, Edwin
Publicado 2015

Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine

por Visser, Nienke, Lourens, Harm Jan, Huls, Gerwin, Bremer, Edwin, Wiersma, Valerie R.
Publicado 2021

Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction

por Hendriks, Djoke, He, Yuan, Koopmans, Iris, Wiersma, Valerie R., van Ginkel, Robert J., Samplonius, Douwe F., Helfrich, Wijnand, Bremer, Edwin
Publicado 2016

Galectin-9 Triggers Neutrophil-Mediated Anticancer Immunity

por Ustyanovska Avtenyuk, Natasha, Choukrani, Ghizlane, Ammatuna, Emanuele, Niki, Toshiro, Cendrowicz, Ewa, Lourens, Harm Jan, Huls, Gerwin, Wiersma, Valerie R., Bremer, Edwin
Publicado 2021

The Decrease in Serum sRAGE Levels Upon Smoking is Associated with Activated Neutrophils

por Wiersma, Valerie R., Hoonhorst, Susan J. M., ten Hacken, Nick H. T., van den Berge, Maarten, Slebos, Dirk-Jan, Pouwels, Simon D.
Publicado 2022

EGFR-selective activation of CD27 co-stimulatory signaling by a bispecific antibody enhances anti-tumor activity of T cells

por Melo, Vinicio, Nelemans, Levi Collin, Vlaming, Martijn, Lourens, Harm Jan, Wiersma, Valerie R., Bilemjian, Vrouyr, Huls, Gerwin, de Bruyn, Marco, Bremer, Edwin
Publicado 2023

Acute cigarette smoke‐induced eQTL affects formyl peptide receptor expression and lung function

por Pouwels, Simon D., Wiersma, Valerie R., Fokkema, Immeke E., Berg, Marijn, ten Hacken, Nick H.T., van den Berge, Maarten, Heijink, Irene, Faiz, Alen
Publicado 2020

Reply to Biswas: Acute and Chronic Effects of Cigarette Smoking on sRAGE

por Pouwels, Simon D., Klont, Frank, Kwiatkowski, Marcel, Wiersma, Valerie R., Faiz, Alen, van den Berge, Maarten, Horvatovich, Péter, Bischoff, Rainer, ten Hacken, Nick H. T.
Publicado 2019

Galectin-9 Is a Possible Promoter of Immunopathology in Rheumatoid Arthritis by Activation of Peptidyl Arginine Deiminase 4 (PAD-4) in Granulocytes

por Wiersma, Valerie R., Clarke, Alex, Pouwels, Simon D., Perry, Elizabeth, Abdullah, Trefa M., Kelly, Clive, Soyza, Anthony De, Hutchinson, David, Eggleton, Paul, Bremer, Edwin
Publicado 2019

Galectin-9 has non-apoptotic cytotoxic activity toward acute myeloid leukemia independent of cytarabine resistance

por Choukrani, Ghizlane, Visser, Nienke, Ustyanovska Avtenyuk, Natasha, Olthuis, Mirjam, Marsman, Glenn, Ammatuna, Emanuele, Lourens, Harm Jan, Niki, Toshiro, Huls, Gerwin, Bremer, Edwin, Wiersma, Valerie R.
Publicado 2023

The Glycan-Binding Protein Galectin-9 Has Direct Apoptotic Activity toward Melanoma Cells

por Wiersma, Valerie R, de Bruyn, Marco, van Ginkel, Robert J, Sigar, Emily, Hirashima, Mitsuomi, Niki, Toshiro, Nishi, Nozomu, Samplonius, Douwe F, Helfrich, Wijnand, Bremer, Edwin
Publicado 2012

The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide

por Pandya, Unnati M., Egbuta, Chinaza, Abdullah Norman, Trefa M., Chiang, Chih-Yuan (Edward), Wiersma, Valerie R., Panchal, Rekha G., Bremer, Edwin, Eggleton, Paul, Gold, Leslie I
Publicado 2019

Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis

por He, Yuan, Bouwstra, Renee, Wiersma, Valerie R., de Jong, Mathilde, Jan Lourens, Harm, Fehrmann, Rudolf, de Bruyn, Marco, Ammatuna, Emanuele, Huls, Gerwin, van Meerten, Tom, Bremer, Edwin
Publicado 2019

Galectin-9 Activates and Expands Human T-Helper 1 Cells

por Gooden, Marloes J. M., Wiersma, Valerie R., Samplonius, Douwe F., Gerssen, Jurjen, van Ginkel, Robert J., Nijman, Hans W., Hirashima, Mitsuomi, Niki, Toshiro, Eggleton, Paul, Helfrich, Wijnand, Bremer, Edwin
Publicado 2013

CD20-selective inhibition of CD47-SIRPα “don't eat me” signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab...

por van Bommel, Peter E., He, Yuan, Schepel, Ilona, Hendriks, Mark A. J. M., Wiersma, Valerie R., van Ginkel, Robert J., van Meerten, Tom, Ammatuna, Emanuele, Huls, Gerwin, Samplonius, Douwe F., Helfrich, Wijnand, Bremer, Edwin
Publicado 2017

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux

por Wiersma, Valerie R, de Bruyn, Marco, Wei, Yunwei, van Ginkel, Robert J, Hirashima, Mitsuomi, Niki, Toshiro, Nishi, Nozomu, Zhou, Jin, Pouwels, Simon D, Samplonius, Douwe F, Nijman, Hans W, Eggleton, Paul, Helfrich, Wijnand, Bremer, Edwin
Publicado 2015