The Extracellular Loop 2 (ECL2) of the Human Histamine H(4) Receptor Substantially Contributes to Ligand Binding and Constitutive Activity

por Wifling, David, Bernhardt, Günther, Dove, Stefan, Buschauer, Armin
Publicado 2015

Structure‐Activity Relationship of Hetarylpropylguanidines Aiming at the Development of Selective Histamine Receptor Ligands(†)

por Pockes, Steffen, Wifling, David, Buschauer, Armin, Elz, Sigurd
Publicado 2019

Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H(2) Receptor Agonists†

por Pockes, Steffen, Wifling, David, Keller, Max, Buschauer, Armin, Elz, Sigurd
Publicado 2018

Luciferase Reporter Gene Assay on Human, Murine and Rat Histamine H(4) Receptor Orthologs: Correlations and Discrepancies between Distal and Proximal Readouts

por Nordemann, Uwe, Wifling, David, Schnell, David, Bernhardt, Günther, Stark, Holger, Seifert, Roland, Buschauer, Armin
Publicado 2013

Basal Histamine H(4) Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif

por Wifling, David, Pfleger, Christopher, Kaindl, Jonas, Ibrahim, Passainte, Kling, Ralf C., Buschauer, Armin, Gohlke, Holger, Clark, Timothy
Publicado 2019

Structural basis of ligand binding modes at the neuropeptide Y Y(1) receptor

por Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brian J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David, Bernhardt, Guenther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C., Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin, Wu, Beili
Publicado 2018

Pandemic drugs at pandemic speed: infrastructure for accelerating COVID-19 drug discovery with hybrid machine learning- and physics-based simulations on high-performance computers

por Bhati, Agastya P, Wan, Shunzhou, Alfè, Dario, Clyde, Austin R, Bode, Mathis, Tan, Li, Titov, Mikhail, Merzky, Andre, Turilli, Matteo, Jha, Shantenu, Highfield, Roger R, Rocchia, Walter, Scafuri, Nicola, Succi, Sauro, Kranzlmüller, Dieter, Mathias, Gerald, Wifling, David, Donon, Yann, Di Meglio, Alberto, Vallecorsa, Sofia, Ma, Heng, Trifan, Anda, Ramanathan, Arvind, Brettin, Tom, Partin, Alexander, Xia, Fangfang, Duan, Xiaotan, Stevens, Rick, Coveney, Peter V
Publicado 2021

Pandemic drugs at pandemic speed: infrastructure for accelerating COVID-19 drug discovery with hybrid machine learning- and physics-based simulations on high-performance computers

por Bhati, Agastya P., Wan, Shunzhou, Alfè, Dario, Clyde, Austin R., Bode, Mathis, Tan, Li, Titov, Mikhail, Merzky, Andre, Turilli, Matteo, Jha, Shantenu, Highfield, Roger R., Rocchia, Walter, Scafuri, Nicola, Succi, Sauro, Kranzlmüller, Dieter, Mathias, Gerald, Wifling, David, Donon, Yann, Di Meglio, Alberto, Vallecorsa, Sofia, Ma, Heng, Trifan, Anda, Ramanathan, Arvind, Brettin, Tom, Partin, Alexander, Xia, Fangfang, Duan, Xiaotan, Stevens, Rick, Coveney, Peter V.
Publicado 2021