The “Glutamate Switch” : a link between ATPase activity and ligand binding in AAA+ proteins

por Zhang, Xiaodong, Wigley, Dale B.
Publicado 2008

Structural features of Chi recognition in AddAB with implications for RecBCD

por Wilkinson, Martin, Wigley, Dale B
Publicado 2014

DNA translocation mechanism of an XPD family helicase

por Cheng, Kaiying, Wigley, Dale B
Publicado 2018

INO80 and SWR1 complexes: the non-identical twins of chromatin remodelling

por Willhoft, Oliver, Wigley, Dale B
Publicado 2020

Mechanism for nuclease regulation in RecBCD

por Wilkinson, Martin, Chaban, Yuriy, Wigley, Dale B
Publicado 2016

A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair

por Cheng, Kaiying, Wilkinson, Martin, Chaban, Yuriy, Wigley, Dale B.
Publicado 2020

Synergy and antagonism in regulation of recombinant human INO80 chromatin remodeling complex

por Willhoft, Oliver, Bythell-Douglas, Rohan, McCormack, Elizabeth A., Wigley, Dale B.
Publicado 2016

Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System

por Wilkinson, Martin, Drabavicius, Gediminas, Silanskas, Arunas, Gasiunas, Giedrius, Siksnys, Virginijus, Wigley, Dale B.
Publicado 2019

Insights into Chi recognition from the structure of an AddAB-type helicase–nuclease complex

por Saikrishnan, Kayarat, Yeeles, Joseph T, Gilhooly, Neville S, Krajewski, Wojciech W, Dillingham, Mark S, Wigley, Dale B
Publicado 2012

Structural basis for translocation by AddAB helicase/nuclease and its arrest at Chi sites

por Krajewski, Wojciech W., Fu, Xin, Wilkinson, Martin, Cronin, Nora B., Dillingham, Mark S., Wigley, Dale B.
Publicado 2014

CryoEM structures of the human INO80 chromatin remodelling complex

por Aramayo, Ricardo J., Willhoft, Oliver, Ayala, Rafael, Bythell-Douglas, Rohan, Wigley, Dale B., Zhang, Xiaodong
Publicado 2017

Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

por Wilkinson, Martin, Wilkinson, Oliver J, Feyerherm, Connie, Fletcher, Emma E, Wigley, Dale B, Dillingham, Mark S
Publicado 2022

Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination

por Gilhooly, Neville S., Carrasco, Carolina, Gollnick, Benjamin, Wilkinson, Martin, Wigley, Dale B., Moreno-Herrero, Fernando, Dillingham, Mark S.
Publicado 2016

Functional characterization and architecture of recombinant yeast SWR1 histone exchange complex

por Lin, Chia-Liang, Chaban, Yuriy, Rees, David M., McCormack, Elizabeth A., Ocloo, Lorraine, Wigley, Dale B.
Publicado 2017

Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones

por Wilkinson, Martin, Troman, Lucy, Wan Nur Ismah, Wan AK, Chaban, Yuriy, Avison, Matthew B, Dillingham, Mark S, Wigley, Dale B
Publicado 2016

Crosstalk within a functional INO80 complex dimer regulates nucleosome sliding

por Willhoft, Oliver, McCormack, Elizabeth A, Aramayo, Ricardo J, Bythell-Douglas, Rohan, Ocloo, Lorraine, Zhang, Xiaodong, Wigley, Dale B
Publicado 2017

CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair

por Wilkinson, Oliver J, Martín-González, Alejandro, Kang, Haejoo, Northall, Sarah J, Wigley, Dale B, Moreno-Herrero, Fernando, Dillingham, Mark Simon
Publicado 2019

The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase

por Sanders, Kelly, Lin, Chia-Liang, Smith, Abigail J., Cronin, Nora, Fisher, Gemma, Eftychidis, Vasileios, McGlynn, Peter, Savery, Nigel J., Wigley, Dale B., Dillingham, Mark S.
Publicado 2017

The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis

por Carrat, Gaelle R., Haythorne, Elizabeth, Tomas, Alejandra, Haataja, Leena, Müller, Andreas, Arvan, Peter, Piunti, Alexandra, Cheng, Kaiying, Huang, Mutian, Pullen, Timothy J., Georgiadou, Eleni, Stylianides, Theodoros, Amirruddin, Nur Shabrina, Salem, Victoria, Distaso, Walter, Cakebread, Andrew, Heesom, Kate J., Lewis, Philip A., Hodson, David J., Briant, Linford J., Fung, Annie C.H., Sessions, Richard B., Alpy, Fabien, Kong, Alice P.S., Benke, Peter I., Torta, Federico, Teo, Adrian Kee Keong, Leclerc, Isabelle, Solimena, Michele, Wigley, Dale B., Rutter, Guy A.
Publicado 2020