RELATIONSHIP BETWEEN SARS-COV-2 VIRAL LOAD, ANTIGEN POSITIVITY AND INFECTIOUS TITER

por Germuskova, Z., Strobl, M., Mock, T., Hortsch, S., Wildum, S., Bauer, R.
Publicado 2023

Mapping of mitochondrial mRNA termini in Arabidopsis thaliana: t-elements contribute to 5′ and 3′ end formation

por Forner, Joachim, Weber, Bärbel, Thuss, Sabine, Wildum, Steffen, Binder, Stefan
Publicado 2007

Investigating the transmission of baloxavir‐resistant influenza viruses from treated index patients to untreated household contacts in the BLOCKSTONE study

por Harding, Joanne, Bernasconi, Corrado, Williams, Sarah, Wildum, Steffen, Kinoshita, Masahiro, Uehara, Takeki, Hurt, Aeron C.
Publicado 2023

Comprehensive assessment of amino acid substitutions in the trimeric RNA polymerase complex of influenza A virus detected in clinical trials of baloxavir marboxil

por Hashimoto, Takashi, Baba, Keiko, Inoue, Kae, Okane, Miyako, Hata, Satoshi, Shishido, Takao, Naito, Akira, Wildum, Steffen, Omoto, Shinya
Publicado 2020

Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children: A Randomized, Double-blind, Active Controlled Phase 3 Safety and Efficacy Trial (miniSTONE-2)

por Baker, Jeffrey, Block, Stanley L., Matharu, Balpreet, Burleigh Macutkiewicz, Laura, Wildum, Steffen, Dimonaco, Sophie, Collinson, Neil, Clinch, Barry, Piedra, Pedro A.
Publicado 2020

A Phase 2 Randomized Trial Evaluating the Antiviral Activity and Safety of the Direct-Acting Antiviral Bemnifosbuvir in Ambulatory Patients with Mild or Moderate COVID-19 (MOONSONG...

por Boffito, Marta, Dolan, Eamon, Singh, Karishma, Holmes, William, Wildum, Steffen, Horga, Arantxa, Pietropaolo, Keith, Zhou, Xiao-Jian, Clinch, Barry, Collinson, Neil, Ukachukwu, Vincent
Publicado 2023

Assessing the fitness of a dual-antiviral drug resistant human influenza virus in the ferret model

por Stannard, Harry L., Mifsud, Edin J., Wildum, Steffen, Brown, Sook Kwan, Koszalka, Paulina, Shishido, Takao, Kojima, Satoshi, Omoto, Shinya, Baba, Keiko, Kuhlbusch, Klaus, Hurt, Aeron C., Barr, Ian G.
Publicado 2022

Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon‐α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus

por Menne, Stephan, Wildum, Steffen, Steiner, Guido, Suresh, Manasa, Korolowicz, Kyle, Balarezo, Maria, Yon, Changsuek, Murreddu, Marta, Hong, Xupeng, Kallakury, Bhaskar V., Tucker, Robin, Yang, Song, Young, John A.T., Javanbakht, Hassan
Publicado 2020

Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins

por Sauter, Daniel, Hotter, Dominik, Van Driessche, Benoît, Stürzel, Christina M., Kluge, Silvia F., Wildum, Steffen, Yu, Hangxing, Baumann, Bernd, Wirth, Thomas, Plantier, Jean-Christophe, Leoz, Marie, Hahn, Beatrice H., Van Lint, Carine, Kirchhoff, Frank
Publicado 2015

Oral bemnifosbuvir (AT-527) vs placebo in patients with mild-to-moderate COVID-19 in an outpatient setting (MORNINGSKY)

por Horga, Arantxa, Saenz, Rebecca, Yilmaz, Gürdal, Simón-Campos, Abraham, Pietropaolo, Keith, Stubbings, William J, Collinson, Neil, Ishak, Laura, Zrinscak, Barbara, Belanger, Bruce, Granier, Catherine, Lin, Kai, C Hurt, Aeron, Zhou, Xiao-Jian, Wildum, Steffen, Hammond, Janet
Publicado 2023

Prognostic value of severe acute respiratory syndrome coronavirus‐2 viral load and antibodies in patients hospitalized with COVID‐19

por Bauer, Rebecca N., Teterina, Anastasia, Shivram, Haridha, McBride, Jacqueline, Rosenberger, Carrie M., Cai, Fang, Bao, Min, Tsai, Larry, Gordon, Oliver, Lee, Ivan T., Wallin, Jeffrey J., Porter, Danielle, Juneja, Kavita, Camus, Gregory, Rosas, Ivan O., Wildum, Steffen
Publicado 2023

Toll-Like Receptor 7 Agonist RG7854 Mediates Therapeutic Efficacy and Seroconversion in Woodchucks With Chronic Hepatitis B

por Wildum, Steffen, Korolowicz, Kyle E., Suresh, Manasa, Steiner, Guido, Dai, Lue, Li, Bin, Yon, Changsuek, De Vera Mudry, Maria Cristina, Regenass-Lechner, Franziska, Huang, Xu, Hong, Xupeng, Murreddu, Marta G., Kallakury, Bhaskar V., Young, John A. T., Menne, Stephan
Publicado 2022

Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms

por Zhou, Zheng, Hu, Taishan, Zhou, Xue, Wildum, Steffen, Garcia-Alcalde, Fernando, Xu, Zhiheng, Wu, Daitze, Mao, Yi, Tian, Xiaojun, Zhou, Yuan, Shen, Fang, Zhang, Zhisen, Tang, Guozhi, Najera, Isabel, Yang, Guang, Shen, Hong C., Young, John A. T., Qin, Ning
Publicado 2017

Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model

por Lee, Leo Y, Zhou, Jie, Koszalka, Paulina, Frise, Rebecca, Farrukee, Rubaiyea, Baba, Keiko, Miah, Shahjahan, Shishido, Takao, Galiano, Monica, Hashimoto, Takashi, Omoto, Shinya, Uehara, Takeki, Mifsud, Edin J., Collinson, Neil, Kuhlbusch, Klaus, Clinch, Barry, Wildum, Steffen, Barclay, Wendy S., Hurt, Aeron C.
Publicado 2021

Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission

por Lee, Leo Yi Yang, Zhou, Jie, Frise, Rebecca, Goldhill, Daniel H., Koszalka, Paulina, Mifsud, Edin J., Baba, Kaoru, Noda, Takahiro, Ando, Yoshinori, Sato, Kenji, Yuki, Aoe-Ishikawa, Shishido, Takao, Uehara, Takeki, Wildum, Steffen, Zwanziger, Elke, Collinson, Neil, Kuhlbusch, Klaus, Clinch, Barry, Hurt, Aeron C., Barclay, Wendy S.
Publicado 2020

Machine-learning based patient classification using Hepatitis B virus full-length genome quasispecies from Asian and European cohorts

por Mueller-Breckenridge, Alan J., Garcia-Alcalde, Fernando, Wildum, Steffen, Smits, Saskia L., de Man, Robert A., van Campenhout, Margo J. H., Brouwer, Willem P., Niu, Jianjun, Young, John A. T., Najera, Isabel, Zhu, Lina, Wu, Daitze, Racek, Tomas, Hundie, Gadissa Bedada, Lin, Yong, Boucher, Charles A., van de Vijver, David, Haagmans, Bart L.
Publicado 2019

Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA)

por Rosas, Ivan O., Bräu, Norbert, Waters, Michael, Go, Ronaldo C., Malhotra, Atul, Hunter, Bradley D., Bhagani, Sanjay, Skiest, Daniel, Savic, Sinisa, Douglas, Ivor S., Garcia-Diaz, Julia, Aziz, Mariam S., Cooper, Nichola, Youngstein, Taryn, Sorbo, Lorenzo Del, Zerda, David J. De La, Ustianowski, Andrew, Gracian, Antonio Cubillo, Blyth, Kevin G., Carratalà, Jordi, François, Bruno, Benfield, Thomas, Haslem, Derrick, Bonfanti, Paolo, van der Leest, Cor H., Rohatgi, Nidhi, Wiese, Lothar, Luyt, Charles Edouard, Bauer, Rebecca N., Cai, Fang, Lee, Ivan T., Matharu, Balpreet, Metcalf, Louis, Wildum, Steffen, Graham, Emily, Tsai, Larry, Bao, Min
Publicado 2022