Programmable RNA-Guided Large DNA Transgenesis by CRISPR/Cas9 and Site-Specific Integrase Bxb1

por Hosur, Vishnu, Low, Benjamin E., Wiles, Michael V.
Publicado 2022

Author Correction: Efficient targeted transgenesis of large donor DNA into multiple mouse genetic backgrounds using bacteriophage Bxb1 integrase

por Low, Benjamin E., Hosur, Vishnu, Lesbirel, Simon, Wiles, Michael V.
Publicado 2023

CRISPR–Cas9-mediated genome editing and guide RNA design

por Wiles, Michael V., Qin, Wenning, Cheng, Albert W., Wang, Haoyi
Publicado 2015

Efficient targeted transgenesis of large donor DNA into multiple mouse genetic backgrounds using bacteriophage Bxb1 integrase

por Low, Benjamin E., Hosur, Vishnu, Lesbirel, Simon, Wiles, Michael V.
Publicado 2022

Conserving, Distributing and Managing Genetically Modified Mouse Lines by Sperm Cryopreservation

por Ostermeier, G. Charles, Wiles, Michael V., Farley, Jane S., Taft, Robert A.
Publicado 2008

Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis

por Hosur, Vishnu, Low, Benjamin E., Shultz, Leonard D., Wiles, Michael V.
Publicado 2017

Mouse Estrous Cycle Identification Tool and Images

por Byers, Shannon L., Wiles, Michael V., Dunn, Sadie L., Taft, Robert A.
Publicado 2012

Generation of improved humanized mouse models for human infectious diseases

por Brehm, Michael A., Wiles, Michael V., Greiner, Dale L., Shultz, Leonard D.
Publicado 2014

Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice

por Low, Benjamin E., Christianson, Gregory J., Lowell, Emily, Qin, Wenning, Wiles, Michael V.
Publicado 2020

Interleukin 6 Influences Germinal Center Development and Antibody Production via a Contribution of C3 Complement Component

por Kopf, Manfred, Herren, Suzanne, Wiles, Michael V., Pepys, Mark B., Kosco-Vilbois, Marie H.
Publicado 1998

ADAM17 is essential for ectodomain shedding of the EGF‐receptor ligand amphiregulin

por Hosur, Vishnu, Farley, Michelle L., Burzenski, Lisa M., Shultz, Leonard D., Wiles, Michael V.
Publicado 2018

Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3, Is Dependent on the Crb1(rd8) Allele

por Chang, Bo, FitzMaurice, Bernard, Wang, Jieping, Low, Benjamin E., Wiles, Michael V., Nishina, Patsy M.
Publicado 2018

Role of MicroRNA in Inflammatory Bowel Disease: Clinical Evidence and the Development of Preclinical Animal Models

por Suri, Kanika, Bubier, Jason A., Wiles, Michael V., Shultz, Leonard D., Amiji, Mansoor M., Hosur, Vishnu
Publicado 2021

Inactive rhomboid proteins RHBDF1 and RHBDF2 (iRhoms): a decade of research in murine models

por Burzenski, Lisa M., Low, Benjamin E., Kohar, Vivek, Shultz, Leonard D., Wiles, Michael V., Hosur, Vishnu
Publicado 2021

The Perfect Host: A Mouse Host Embryo Facilitating More Efficient Germ Line Transmission of Genetically Modified Embryonic Stem Cells

por Taft, Robert A., Low, Benjamin E., Byers, Shannon L., Murray, Stephen A., Kutny, Peter, Wiles, Michael V.
Publicado 2013

Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs

por Roopenian, Derry C, Low, Benjamin E, Christianson, Gregory J, Proetzel, Gabriele, Sproule, Thomas J, Wiles, Michael V
Publicado 2015

RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?

por Hosur, Vishnu, Farley, Michelle L., Low, Benjamin E., Burzenski, Lisa M., Shultz, Leonard D., Wiles, Michael V.
Publicado 2018

Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation

por Hosur, Vishnu, Low, Benjamin E., Li, Daniel, Stafford, Grace A., Kohar, Vivek, Shultz, Leonard D., Wiles, Michael V.
Publicado 2020

Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands

por Farris, M. Heath, Texter, Pamela A., Mora, Agustin A., Wiles, Michael V., Mac Garrigle, Ellen F., Klaus, Sybil A., Rosfjord, Kristine
Publicado 2020

Loss of TRP53 (p53) accelerates tumorigenesis and changes the tumor spectrum of SJL/J mice

por Branca, Jane A, Low, Benjamin E, Saxl, Ruth L, Sargent, Jennifer K, Doty, Rosalinda A, Wiles, Michael V, Dumont, Beth L, Hasham, Muneer G
Publicado 2020