MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach

por Stehn, Justine R., Floyd, Scott R., Wilker, Erik W., Reinhardt, H. Christian, Clarke, Scott M., Huang, Qiuying, Polakiewicz, Roberto D., Sonenberg, Nahum, Kong, Yi Wen, Yaffe, Michael B.
Publicado 2023

FT-6876, a Potent and Selective Inhibitor of CBP/p300, is Active in Preclinical Models of Androgen Receptor-Positive Breast Cancer

por Caligiuri, Maureen, Williams, Grace L., Castro, Jennifer, Battalagine, Linda, Wilker, Erik, Yao, Lili, Schiller, Shawn, Toms, Angela, Li, Ping, Pardo, Eneida, Graves, Bradford, Azofeifa, Joey, Chicas, Agustin, Herbertz, Torsten, Lai, Maria, Basken, Joel, Wood, Kenneth W., Xu, Qunli, Guichard, Sylvie M.
Publicado 2023

Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer

por Simoneau, Antoine, Engel, Justin L., Bandi, Madhavi, Lazarides, Katherine, Liu, Shangtao, Meier, Samuel R., Choi, Ashley H., Zhang, Hongxiang, Shen, Binzhang, Martires, Lauren, Gotur, Deepali, Pham, Truc V., Li, Fang, Gu, Lina, Gong, Shanzhong, Zhang, Minjie, Wilker, Erik, Pan, Xuewen, Whittington, Douglas A., Throner, Scott, Maxwell, John P., Chen, Yingnan, Yu, Yi, Huang, Alan, Andersen, Jannik N., Feng, Tianshu
Publicado 2023

VRK1 Is a Synthetic–Lethal Target in VRK2-Deficient Glioblastoma

por Shields, Julie A., Meier, Samuel R., Bandi, Madhavi, Mulkearns-Hubert, Erin E., Hajdari, Nicole, Ferdinez, Maria Dam, Engel, Justin L., Silver, Daniel J., Shen, Binzhang, Zhang, Wenhai, Hubert, Christopher G., Mitchell, Kelly, Shakya, Sajina, Zhao, Shan-Chuan, Bejnood, Alborz, Zhang, Minjie, Tjin Tham Sjin, Robert, Wilker, Erik, Lathia, Justin D., Andersen, Jannik N., Chen, Yingnan, Li, Fang, Weber, Barbara, Huang, Alan, Emmanuel, Natasha
Publicado 2022