Splicing factor SRSF6 promotes hyperplasia of sensitized skin

por Jensen, Mads A., Wilkinson, John E., Krainer, Adrian R.
Publicado 2014

Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin(-/-) Mice

por Markham, Bruce E., Kernodle, Stace, Nemzek, Jean, Wilkinson, John E., Sigler, Robert
Publicado 2015

A Pipeline for Drug Target Identification and Validation

por Manchado, Eusebio, Huang, Chun-Hao, Tasdemir, Nilgun, Tschaharganeh, Darjus F., Wilkinson, John E., Lowe, Scott W.
Publicado 2017

R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine

por Han, Teng, Schatoff, Emma M., Murphy, Charles, Zafra, Maria Paz, Wilkinson, John E., Elemento, Olivier, Dow, Lukas E.
Publicado 2017

Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations

por Bauler, Timothy J., Kamiya, Nobuhiro, Lapinski, Philip E., Langewisch, Eric, Mishina, Yuji, Wilkinson, John E., Feng, Gen-Sheng, King, Philip D.
Publicado 2011

Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition

por Bolden, Jessica E., Tasdemir, Nilgun, Dow, Lukas E., van Es, Johan H., Wilkinson, John E., Zhao, Zhen, Clevers, Hans, Lowe, Scott W.
Publicado 2014

A Mouse Model for Human Norovirus

por Taube, Stefan, Kolawole, Abimbola O., Höhne, Marina, Wilkinson, John E., Handley, Scott A., Perry, Jeffrey W., Thackray, Larissa B., Akkina, Ramesh, Wobus, Christiane E.
Publicado 2013

Differential susceptibility of C57BL/6NCr and B6.Cg-Ptprc(a )mice to commensal bacteria after whole body irradiation in translational bone marrow transplant studies

por Duran-Struuck, Raimon, Hartigan, Adam, Clouthier, Shawn G, Dyson, Melissa C, Lowler, Kathi, Gatza, Erin, Tawara, Isao, Toubai, Tomomi, Weisiger, Elisabeth, Hugunin, Kelly, Reddy, Pavan, Wilkinson, John E
Publicado 2008

PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils

por Song, Dongyan, Adrover, Jose M., Felice, Christy, Christensen, Lisa N., He, Xue-Yan, Merrill, Joseph R., Wilkinson, John E., Janowitz, Tobias, Lyons, Scott K., Egeblad, Mikala, Tonks, Nicholas K.
Publicado 2022

Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant lesions

por Feigman, Mary J., Moss, Matthew A., Chen, Chen, Cyrill, Samantha L., Ciccone, Michael F., Trousdell, Marygrace C., Yang, Shih-Ting, Frey, Wesley D., Wilkinson, John E., dos Santos, Camila O.
Publicado 2020

Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases

por Taranda, Julian, Mathew, Grinu, Watrud, Kaitlin, El-Amine, Nour, Lee, Matthew F., Elowsky, Corey, Bludova, Anastasiia, Avelar, Sintia Escobar, Nowak, Dawid G., Wee, Tse-Luen, Wilkinson, John E., Trotman, Lloyd C., Osten, Pavel
Publicado 2021

Transcription Factors OVOL1 and OVOL2 Induce the Mesenchymal to Epithelial Transition in Human Cancer

por Roca, Hernan, Hernandez, James, Weidner, Savannah, McEachin, Richard C., Fuller, David, Sud, Sudha, Schumann, Taibriana, Wilkinson, John E., Zaslavsky, Alexander, Li, Hangwen, Maher, Christopher A., Daignault-Newton, Stephanie, Healy, Patrick N., Pienta, Kenneth J.
Publicado 2013

Acarbose has sex-dependent and -independent effects on age-related physical function, cardiac health, and lipid biology

por Herrera, Jonathan J., Louzon, Sean, Pifer, Kaitlyn, Leander, Danielle, Merrihew, Gennifer E., Park, Jea H., Szczesniak, Kate, Whitson, Jeremy, Wilkinson, John E., Fiehn, Oliver, MacCoss, Michael J., Day, Sharlene M., Miller, Richard A., Garratt, Michael
Publicado 2020

Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

por Somasundara, Amritha Varshini Hanasoge, Moss, Matthew A., Feigman, Mary J., Chen, Chen, Cyrill, Samantha L., Ciccone, Michael F., Trousdell, Marygrace C., Vollbrecht, Macy, Li, Siran, Kendall, Jude, Beyaz, Semir, Wilkinson, John E., dos Santos, Camila O.
Publicado 2021

Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer

por Paffenholz, Stella V., Salvagno, Camilla, Ho, Yu-Jui, Limjoco, Matthew, Baslan, Timour, Tian, Sha, Kulick, Amanda, de Stanchina, Elisa, Wilkinson, John E., Barriga, Francisco M., Zamarin, Dmitriy, Cubillos-Ruiz, Juan R., Leibold, Josef, Lowe, Scott W.
Publicado 2022

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer

por Huang, Yu-Han, Klingbeil, Olaf, He, Xue-Yan, Wu, Xiaoli S., Arun, Gayatri, Lu, Bin, Somerville, Tim D.D., Milazzo, Joseph P., Wilkinson, John E., Demerdash, Osama E., Spector, David L., Egeblad, Mikala, Shi, Junwei, Vakoc, Christopher R.
Publicado 2018

ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis

por Wang, Lidong, Yang, Huibin, Abel, Ethan V., Ney, Gina M., Palmbos, Phillip L., Bednar, Filip, Zhang, Yaqing, Leflein, Jacob, Waghray, Meghna, Owens, Scott, Wilkinson, John E., Prasad, Jayendra, Ljungman, Mats, Rhim, Andrew D., Pasca di Magliano, Marina, Simeone, Diane M.
Publicado 2015

The PHLPP2 phosphatase is a druggable driver of prostate cancer progression

por Nowak, Dawid G., Katsenelson, Ksenya Cohen, Watrud, Kaitlin E., Chen, Muhan, Mathew, Grinu, D’Andrea, Vincent D., Lee, Matthew F., Swamynathan, Manojit Mosur, Casanova-Salas, Irene, Jibilian, Megan C., Buckholtz, Caroline L., Ambrico, Alexandra J., Pan, Chun-Hao, Wilkinson, John E., Newton, Alexandra C., Trotman, Lloyd C.
Publicado 2019

A gene-environment induced epigenetic program initiates tumorigenesis

por Alonso-Curbelo, Direna, Ho, Yu-Jui, Burdziak, Cassandra, Maag, Jesper L.V., Morris, John P., Chandwani, Rohit, Chen, Hsuan-An, Tsanov, Kaloyan M., Barriga, Francisco M., Luan, Wei, Tasdemir, Nilgun, Livshits, Geulah, Azizi, Elham, Chun, Jaeyoung, Wilkinson, John E., Mazutis, Linas, Leach, Steven D., Koche, Richard, Pe’er, Dana, Lowe, Scott W.
Publicado 2021

A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets

por Li, Xiang, Huang, Chun-Hao, Sánchez-Rivera, Francisco J., Kennedy, Margaret C., Tschaharganeh, Darjus F., Morris, John P., Montinaro, Antonella, O'Rourke, Kevin P., Banito, Ana, Wilkinson, John E., Chen, Chi-Chao, Ho, Yu-Jui, Dow, Lukas E., Tian, Sha, Luan, Wei, de Stanchina, Elisa, Zhang, Tinghu, Gray, Nathanael S., Walczak, Henning, Lowe, Scott W.
Publicado 2022