Unravelling the genetic architecture of human complex traits through whole genome sequencing

por Bocher, Ozvan, Willer, Cristen J., Zeggini, Eleftheria
Publicado 2023

METAL: fast and efficient meta-analysis of genomewide association scans

por Willer, Cristen J., Li, Yun, Abecasis, Gonçalo R.
Publicado 2010

Genome-scale CRISPR screening for modifiers of cellular LDL uptake

por Emmer, Brian T., Sherman, Emily J., Lascuna, Paul J., Graham, Sarah E., Willer, Cristen J., Ginsburg, David
Publicado 2021

Incorporating family disease history and controlling case–control imbalance for population-based genetic association studies

por Zhuang, Yongwen, Wolford, Brooke N, Nam, Kisung, Bi, Wenjian, Zhou, Wei, Willer, Cristen J, Mukherjee, Bhramar, Lee, Seunggeun
Publicado 2022

LocusZoom: regional visualization of genome-wide association scan results

por Pruim, Randall J., Welch, Ryan P., Sanna, Serena, Teslovich, Tanya M., Chines, Peter S., Gliedt, Terry P., Boehnke, Michael, Abecasis, Gonçalo R., Willer, Cristen J.
Publicado 2010

A Novel Variant in APOB Gene Causes Extremely Low LDL-C Without Known Adverse Effects

por Surakka, Ida, Hornsby, Whitney E., Farhat, Linda, Rubenfire, Melvyn, Fritsche, Lars G., Hveem, Kristian, Chen, Y. Eugene, Brook, Robert D., Willer, Cristen J., Weinberg, Richard L.
Publicado 2020

Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study)

por Brandkvist, Maria, Bjørngaard, Johan Håkon, Ødegård, Rønnaug Astri, Brumpton, Ben, Smith, George Davey, Åsvold, Bjørn Olav, Sund, Erik R., Kvaløy, Kirsti, Willer, Cristen J., Vie, Gunnhild Åberge
Publicado 2020

Identification of cell type specific ACE2 modifiers by CRISPR screening

por Sherman, Emily J., Mirabelli, Carmen, Tang, Vi T., Khan, Taslima G., Leix, Kyle, Kennedy, Andrew A., Graham, Sarah E., Willer, Cristen J., Tai, Andrew W., Sexton, Jonathan Z., Wobus, Christiane E., Emmer, Brian T.
Publicado 2022

The Michigan Genomics Initiative: A biobank linking genotypes and electronic clinical records in Michigan Medicine patients

por Zawistowski, Matthew, Fritsche, Lars G., Pandit, Anita, Vanderwerff, Brett, Patil, Snehal, Schmidt, Ellen M., VandeHaar, Peter, Willer, Cristen J., Brummett, Chad M., Kheterpal, Sachin, Zhou, Xiang, Boehnke, Michael, Abecasis, Gonçalo R., Zöllner, Sebastian
Publicado 2023

Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

por Brænne, Ingrid, Zeng, Lingyao, Willenborg, Christina, Tragante, Vinicius, Kessler, Thorsten, Willer, Cristen J., Laakso, Markku, Wallentin, Lars, Franks, Paul W., Salomaa, Veikko, Dehghan, Abbas, Meitinger, Thomas, Samani, Nilesh J., Asselbergs, Folkert W., Erdmann, Jeanette, Schunkert, Heribert
Publicado 2017

Exposure and risk factors for COVID-19 and the impact of staying home on Michigan residents

por Wu, Kuan-Han H., Hornsby, Whitney E., Klunder, Bethany, Krause, Amelia, Driscoll, Anisa, Kulka, John, Bickett-Hickok, Ryan, Fellows, Austin, Graham, Sarah, Kaleba, Erin O., Hayek, Salim S., Shi, Xu, Sutton, Nadia R., Douville, Nicholas, Mukherjee, Bhramar, Jamerson, Kenneth, Brummett, Chad M., Willer, Cristen J.
Publicado 2021

A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors

por Brænne, Ingrid, Willenborg, Christina, Tragante, Vinicius, Kessler, Thorsten, Zeng, Lingyao, Reiz, Benedikt, Kleinecke, Mariana, von Ameln, Simon, Willer, Cristen J., Laakso, Markku, Wild, Philipp S., Zeller, Tanja, Wallentin, Lars, Franks, Paul W., Salomaa, Veikko, Dehghan, Abbas, Meitinger, Thomas, Samani, Nilesh J., Asselbergs, Folkert W., Erdmann, Jeanette, Schunkert, Heribert
Publicado 2017

Mitochondrial genome-wide association study of migraine – the HUNT Study

por Børte, Sigrid, Zwart, John-Anker, Skogholt, Anne Heidi, Gabrielsen, Maiken Elvestad, Thomas, Laurent F, Fritsche, Lars G, Surakka, Ida, Nielsen, Jonas B, Zhou, Wei, Wolford, Brooke N, Vigeland, Magnus D, Hagen, Knut, Kristoffersen, Espen Saxhaug, Nyholt, Dale R, Chasman, Daniel I, Brumpton, Ben M, Willer, Cristen J, Winsvold, Bendik S
Publicado 2020

Meta-Analysis of Gene Level Tests for Rare Variant Association

por Liu, Dajiang J., Peloso, Gina M., Zhan, Xiaowei, Holmen, Oddgeir L., Zawistowski, Matthew, Feng, Shuang, Nikpay, Majid, Auer, Paul L., Goel, Anuj, Zhang, He, Peters, Ulrike, Farrall, Martin, Orho-Melander, Marju, Kooperberg, Charles, McPherson, Ruth, Watkins, Hugh, Willer, Cristen J., Hveem, Kristian, Melander, Olle, Kathiresan, Sekar, Abecasis, Gonçalo R.
Publicado 2013

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

por Zhou, Wei, Nielsen, Jonas B., Fritsche, Lars G., Dey, Rounak, Gabrielsen, Maiken E., Wolford, Brooke N., LeFaive, Jonathon, VandeHaar, Peter, Gagliano, Sarah A., Gifford, Aliya, Bastarache, Lisa A., Wei, Wei-Qi, Denny, Joshua C., Lin, Maoxuan, Hveem, Kristian, Kang, Hyun Min, Abecasis, Goncalo R., Willer, Cristen J., Lee, Seunggeun
Publicado 2018

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT

por Moksnes, Marta R., Graham, Sarah E., Wu, Kuan-Han, Hansen, Ailin Falkmo, Gagliano Taliun, Sarah A., Zhou, Wei, Thorstensen, Ketil, Fritsche, Lars G., Gill, Dipender, Mason, Amy, Cucca, Francesco, Schlessinger, David, Abecasis, Gonçalo R., Burgess, Stephen, Åsvold, Bjørn Olav, Nielsen, Jonas B., Hveem, Kristian, Willer, Cristen J., Brumpton, Ben M.
Publicado 2022

Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries

por Surakka, Ida, Wu, Kuan-Han, Hornsby, Whitney, Wolford, Brooke N., Shen, Fred, Zhou, Wei, Huffman, Jennifer E., Pandit, Anita, Hu, Yao, Brumpton, Ben, Skogholt, Anne Heidi, Gabrielsen, Maiken E., Walters, Robin G., Hveem, Kristian, Kooperberg, Charles, Zöllner, Sebastian, Wilson, Peter W.F., Sutton, Nadia R., Daly, Mark J., Neale, Benjamin M., Willer, Cristen J.
Publicado 2023

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

por Graham, Sarah E., Nielsen, Jonas B., Zawistowski, Matthew, Zhou, Wei, Fritsche, Lars G., Gabrielsen, Maiken E., Skogholt, Anne Heidi, Surakka, Ida, Hornsby, Whitney E., Fermin, Damian, Larach, Daniel B., Kheterpal, Sachin, Brummett, Chad M., Lee, Seunggeun, Kang, Hyun Min, Abecasis, Goncalo R., Romundstad, Solfrid, Hallan, Stein, Sampson, Matthew G., Hveem, Kristian, Willer, Cristen J.
Publicado 2019

Meta-analysis of sub-Saharan African studies provides insights into genetic architecture of lipid traits

por Choudhury, Ananyo, Brandenburg, Jean-Tristan, Chikowore, Tinashe, Sengupta, Dhriti, Boua, Palwende Romuald, Crowther, Nigel J., Agongo, Godfred, Asiki, Gershim, Gómez-Olivé, F. Xavier, Kisiangani, Isaac, Maimela, Eric, Masemola-Maphutha, Matshane, Micklesfield, Lisa K., Nonterah, Engelbert A., Norris, Shane A., Sorgho, Hermann, Tinto, Halidou, Tollman, Stephen, Graham, Sarah E., Willer, Cristen J., Hazelhurst, Scott, Ramsay, Michèle
Publicado 2022

Author Correction: Meta-analysis of sub-Saharan African studies provides insights into genetic architecture of lipid traits

por Choudhury, Ananyo, Brandenburg, Jean-Tristan, Chikowore, Tinashe, Sengupta, Dhriti, Boua, Palwende Romuald, Crowther, Nigel J., Agongo, Godfred, Asiki, Gershim, Gómez-Olivé, F. Xavier, Kisiangani, Isaac, Maimela, Eric, Masemola-Maphutha, Matshane, Micklesfield, Lisa K., Nonterah, Engelbert A., Norris, Shane A., Sorgho, Hermann, Tinto, Halidou, Tollman, Stephen, Graham, Sarah E., Willer, Cristen J., Hazelhurst, Scott, Ramsay, Michèle
Publicado 2022