Islet Autoantibody Testing: An End to the Trials and Tribulations?

por Bingley, Polly J., Williams, Alistair J.K.
Publicado 2013

Following the Fate of the Failing β-Cell: New Insights From First-Phase Insulin Responses

por Williams, Alistair J.K., Long, Anna E.
Publicado 2013

Rising Incidence of Type 1 Diabetes Is Associated With Altered Immunophenotype at Diagnosis

por Long, Anna E., Gillespie, Kathleen M., Rokni, Saba, Bingley, Polly J., Williams, Alistair J.K.
Publicado 2012

The Core Cysteines, (C909) of Islet Antigen-2 and (C945) of Islet Antigen-2β, Are Crucial to Autoantibody Binding in Type 1 Diabetes

por Elvers, Karen T., Geoghegan, Ivey, Shoemark, Debbie K., Lampasona, Vito, Bingley, Polly J., Williams, Alistair J.K.
Publicado 2013

Humoral Responses to Islet Antigen-2 and Zinc Transporter 8 Are Attenuated in Patients Carrying HLA-A*24 Alleles at the Onset of Type 1 Diabetes

por Long, Anna E., Gillespie, Kathleen M., Aitken, Rachel J., Goode, Julia C., Bingley, Polly J., Williams, Alistair J.K.
Publicado 2013

Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops

por Marzinotto, Ilaria, Pittman, David L., Williams, Alistair J. K., Long, Anna E., Achenbach, Peter, Schlosser, Michael, Akolkar, Beena, Winter, William E., Lampasona, Vito
Publicado 2023

Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12

por Achenbach, Peter, Hawa, Mohammed I., Krause, Stephanie, Lampasona, Vito, Jerram, Samuel T., Williams, Alistair J. K., Bonifacio, Ezio, Ziegler, Anette G., Leslie, R. David
Publicado 2018

The measurement of autoantibodies to insulin informs diagnosis of diabetes in a childhood population negative for other autoantibodies

por Williams, Claire L., Aitken, Rachel J., Wilson, Isabel V., Mortimer, Georgina L. M., Long, Anna E., Williams, Alistair J. K., Gillespie, Kathleen M.
Publicado 2022

Detection of Antibodies Directed to the N-Terminal Region of GAD Is Dependent on Assay Format and Contributes to Differences in the Specificity of GAD Autoantibody Assays for Type...

por Williams, Alistair J.K., Lampasona, Vito, Schlosser, Michael, Mueller, Patricia W., Pittman, David L., Winter, William E., Akolkar, Beena, Wyatt, Rebecca, Brigatti, Cristina, Krause, Stephanie, Achenbach, Peter
Publicado 2015

Rationale and protocol for the After Diabetes Diagnosis REsearch Support System (ADDRESS): an incident and high risk type 1 diabetes UK cohort study

por Walkey, Helen C, Kaur, Akaal, Bravis, Vassiliki, Godsland, Ian F, Misra, Shivani, Williams, Alistair J K, Bingley, Polly J, Dunger, David B, Oliver, Nick, Johnston, Desmond G
Publicado 2017

Increased levels of anti-BSA antibodies in children with Down syndrome

por Grace, Sian L., Mortimer, Georgina L., Kozhakhmetova, Aizhan, Leveret, Jamie, Newton, Richard, Reimand, Koit, Shield, Julian P. H., Uibo, Raivo, Williams, Alistair J. K., Gillespie, Kathleen M.
Publicado 2023

Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

por Brorsson, Caroline A., Onengut, Suna, Chen, Wei-Min, Wenzlau, Janet, Yu, Liping, Baker, Peter, Williams, Alistair J.K., Bingley, Polly J., Hutton, John C., Eisenbarth, George S., Concannon, Patrick, Rich, Stephen S., Pociot, Flemming
Publicado 2015

Relationship between islet autoantibody status and the clinical characteristics of children and adults with incident type 1 diabetes in a UK cohort

por Bravis, Vassiliki, Kaur, Akaal, Walkey, Helen C, Godsland, Ian F, Misra, Shivani, Bingley, Polly J, Williams, Alistair J K, Dunger, David B, Dayan, Colin M, Peakman, Mark, Oliver, Nick S, Johnston, Desmond G
Publicado 2018

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes

por Williams, Georgina M., Long, Anna E., Wilson, Isabel V., Aitken, Rachel J., Wyatt, Rebecca C., McDonald, Timothy J., Wong, F. Susan, Hattersley, Andrew T., Williams, Alistair J. K., Bingley, Polly J., Gillespie, Kathleen M.
Publicado 2016

Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: the SNAIL study

por Long, Anna E., Wilson, Isabel V., Becker, Dorothy J., Libman, Ingrid M., Arena, Vincent C., Wong, F. Susan, Steck, Andrea K., Rewers, Marian J., Yu, Liping, Achenbach, Peter, Casas, Rosaura, Ludvigsson, Johnny, Williams, Alistair J. K., Gillespie, Kathleen M.
Publicado 2018

Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8(+) T cells and exhibit a distinct CD95(hi) B cell phenotype

por Hanna, Stephanie J., Powell, Wendy E., Long, Anna E., Robinson, Emma J. S., Davies, Joanne, Megson, Clare, Howell, Alexandra, Jones, Taz J., Ladell, Kristin, Price, David A., Dayan, Colin M., Williams, Alistair J. K., Gillespie, Kathleen M., Wong, F. Susan
Publicado 2020

Assessment and Management of Anti-Insulin Autoantibodies in Varying Presentations of Insulin Autoimmune Syndrome

por Church, David, Cardoso, Luís, Kay, Richard G, Williams, Claire L, Freudenthal, Bernard, Clarke, Catriona, Harris, Julie, Moorthy, Myuri, Karra, Efthmia, Gribble, Fiona M, Reimann, Frank, Burling, Keith, Williams, Alistair J K, Munir, Alia, Jones, T Hugh, Führer, Dagmar, Moeller, Lars C, Cohen, Mark, Khoo, Bernard, Halsall, David, Semple, Robert K
Publicado 2018

Type 1 diabetes in Africa: an immunogenetic study in the Amhara of North-West Ethiopia

por Balcha, Shitaye A., Demisse, Abayneh G., Mishra, Rajashree, Vartak, Tanwi, Cousminer, Diana L., Hodge, Kenyaita M., Voight, Benjamin F., Lorenz, Kim, Schwartz, Stanley, Jerram, Samuel T., Gamper, Arla, Holmes, Alice, Wilson, Hannah F., Williams, Alistair J. K., Grant, Struan F. A., Leslie, R. David, Phillips, David I. W., Trimble, Elisabeth R.
Publicado 2020

Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2

por Goenka, Anu, Halliday, Alice, Gregorova, Michaela, Milodowski, Emily, Thomas, Amy, Williamson, Maia Kavanagh, Baum, Holly, Oliver, Elizabeth, Long, Anna E., Knezevic, Lea, Williams, Alistair J.K., Lampasona, Vito, Piemonti, Lorenzo, Gupta, Kapil, Di Bartolo, Natalie, Berger, Imre, Toye, Ashley M., Vipond, Barry, Muir, Peter, Bernatoniene, Jolanta, Bailey, Mick, Gillespie, Kathleen M., Davidson, Andrew D., Wooldridge, Linda, Rivino, Laura, Finn, Adam
Publicado 2021

Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults

por Thomas, Amy C., Oliver, Elizabeth, Baum, Holly E., Gupta, Kapil, Shelley, Kathryn L., Long, Anna E., Jones, Hayley E., Smith, Joyce, Hitchings, Benjamin, di Bartolo, Natalie, Vasileiou, Kate, Rabi, Fruzsina, Alamir, Hanin, Eghleilib, Malak, Francis, Ore, Oliver, Jennifer, Morales-Aza, Begonia, Obst, Ulrike, Shattock, Debbie, Barr, Rachael, Collingwood, Lucy, Duale, Kaltun, Grace, Niall, Livera, Guillaume Gonnage, Bishop, Lindsay, Downing, Harriet, Rodrigues, Fernanda, Timpson, Nicholas, Relton, Caroline L., Toye, Ashley, Woolfson, Derek N., Berger, Imre, Goenka, Anu, Davidson, Andrew D., Gillespie, Kathleen M., Williams, Alistair J. K., Bailey, Mick, Brooks-Pollock, Ellen, Finn, Adam, Halliday, Alice
Publicado 2023