Circulating prostaglandins as biomarkers for colorectal cancer?

por Greenhough, Alexander, Paraskeva, Chris, Williams, Ann C.
Publicado 2015

The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells

por Qualtrough, David, Rees, Phil, Speight, Beverley, Williams, Ann C., Paraskeva, Christos
Publicado 2015

The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells

por Greenhough, Alexander, Wallam, Catherine A., Hicks, Diane J., Moorghen, Moganaden, Williams, Ann C., Paraskeva, Chris
Publicado 2010

The role of B-Cell Lymphoma-3 (BCL-3) in enabling the hallmarks of cancer: implications for the treatment of colorectal carcinogenesis

por Legge, Danny N, Chambers, Adam C, Parker, Christopher T, Timms, Penny, Collard, Tracey J, Williams, Ann C
Publicado 2020

In-silico and in-vitro morphometric analysis of intestinal organoids

por Montes-Olivas, Sandra, Legge, Danny, Lund, Abbie, Fletcher, Alexander G., Williams, Ann C., Marucci, Lucia, Homer, Martin
Publicado 2023

Aspirin and the metabolic hallmark of cancer: novel therapeutic opportunities for colorectal cancer

por Hoskin, Ashley J., Holt, Amy K., Legge, Danny N., Collard, Tracey J., Williams, Ann C., Vincent, Emma E.
Publicado 2023

p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-κB subunit

por O'Hara, Andrew, Simpson, James, Morin, Pierre, Loveridge, Carolyn J., Williams, Ann C., Novo, Sonia M., Stark, Lesley A.
Publicado 2014

BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor beta [TGF-β1] in colorectal tumour cells

por Skeen, Victoria R., Collard, Tracey J., Southern, Samantha L., Greenhough, Alexander, Hague, Angela, Townsend, Paul, Paraskeva, Christos, Williams, Ann C.
Publicado 2012

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells

por Legge, Danny N., Shephard, Alex P., Collard, Tracey J., Greenhough, Alexander, Chambers, Adam C., Clarkson, Richard W., Paraskeva, Christos, Williams, Ann C.
Publicado 2019

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling

por Urban, Bettina C, Collard, Tracey J, Eagle, Catherine J, Southern, Samantha L, Greenhough, Alexander, Hamdollah-Zadeh, Maryam, Ghosh, Anil, Poulsom, Richard, Paraskeva, Christos, Silver, Andrew, Williams, Ann C
Publicado 2016

Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

por Greenhough, Alexander, Bagley, Clare, Heesom, Kate J, Gurevich, David B, Gay, David, Bond, Mark, Collard, Tracey J, Paraskeva, Chris, Martin, Paul, Sansom, Owen J, Malik, Karim, Williams, Ann C
Publicado 2018

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis

por Southern, Samantha L., Collard, Tracey J., Urban, Bettina C, Skeen, Victoria R, Smartt, Helena J, Hague, Angela, Oakley, Fiona, Townsend, Paul A, Perkins, Neil D., Paraskeva, Christos, Williams, Ann C.
Publicado 2011

BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination

por Parker, Christopher, Chambers, Adam C., Flanagan, Dustin J., Ho, Jasmine Wing Yu, Collard, Tracey J., Ngo, Greg, Baird, Duncan M., Timms, Penny, Morgan, Rhys G., Sansom, Owen J., Williams, Ann C.
Publicado 2022

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells

por Morgan, Rhys G., Ridsdale, Jenna, Payne, Megan, Heesom, Kate J., Wilson, Marieangela C., Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C., Blair, Allison, Waterman, Marian L., Tonks, Alex, Darley, Richard L.
Publicado 2019

Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition

por Holt, Amy K., Najumudeen, Arafath K., Collard, Tracey J., Li, Hao, Millett, Laura M., Hoskin, Ashley J., Legge, Danny N., Mortensson, Eleanor M. H., Flanagan, Dustin J., Jones, Nicholas, Kollareddy, Madhu, Timms, Penny, Hitchings, Matthew D., Cronin, James, Sansom, Owen J., Williams, Ann C., Vincent, Emma E.
Publicado 2023

Alternative splicing of TIA‐1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

por Hamdollah Zadeh, Maryam A., Amin, Elianna M., Hoareau-Aveilla, Coralie, Domingo, Enric, Symonds, Kirsty E., Ye, Xi, Heesom, Katherine J., Salmon, Andrew, D'Silva, Olivia, Betteridge, Kai B., Williams, Ann C., Kerr, David J., Salmon, Andrew H.J., Oltean, Sebastian, Midgley, Rachel S., Ladomery, Michael R., Harper, Steven J., Varey, Alexander H.R., Bates, David O.
Publicado 2014

The association between genetically elevated polyunsaturated fatty acids and risk of cancer

por Haycock, Philip C., Borges, Maria Carolina, Burrows, Kimberley, Lemaitre, Rozenn N., Burgess, Stephen, Khankari, Nikhil K., Tsilidis, Konstantinos K., Gaunt, Tom R., Hemani, Gibran, Zheng, Jie, Truong, Therese, Birmann, Brenda M., OMara, Tracy, Spurdle, Amanda B., Iles, Mark M., Law, Matthew H., Slager, Susan L., Saberi Hosnijeh, Fatemeh, Mariosa, Daniela, Cotterchio, Michelle, Cerhan, James R., Peters, Ulrike, Enroth, Stefan, Gharahkhani, Puya, Le Marchand, Loic, Williams, Ann C., Block, Robert C., Amos, Christopher I., Hung, Rayjean J., Zheng, Wei, Gunter, Marc J., Smith, George Davey, Relton, Caroline, Martin, Richard M.
Publicado 2023

Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

por Nounu, Aayah, Richmond, Rebecca C., Stewart, Isobel D., Surendran, Praveen, Wareham, Nicholas J., Butterworth, Adam, Weinstein, Stephanie J., Albanes, Demetrius, Baron, John A., Hopper, John L., Figueiredo, Jane C., Newcomb, Polly A., Lindor, Noralane M., Casey, Graham, Platz, Elizabeth A., Marchand, Loïc Le, Ulrich, Cornelia M., Li, Christopher I., van Dujinhoven, Fränzel J. B., Gsur, Andrea, Campbell, Peter T., Moreno, Víctor, Vodicka, Pavel, Vodickova, Ludmila, Amitay, Efrat, Alwers, Elizabeth, Chang-Claude, Jenny, Sakoda, Lori C., Slattery, Martha L., Schoen, Robert E., Gunter, Marc J., Castellví-Bel, Sergi, Kim, Hyeong-Rok, Kweon, Sun-Seog, Chan, Andrew T., Li, Li, Zheng, Wei, Bishop, D. Timothy, Buchanan, Daniel D., Giles, Graham G., Gruber, Stephen B., Rennert, Gad, Stadler, Zsofia K., Harrison, Tabitha A., Lin, Yi, Keku, Temitope O., Woods, Michael O., Schafmayer, Clemens, Van Guelpen, Bethany, Gallinger, Steven, Hampel, Heather, Berndt, Sonja I., Pharoah, Paul D. P., Lindblom, Annika, Wolk, Alicja, Wu, Anna H., White, Emily, Peters, Ulrike, Drew, David A., Scherer, Dominique, Bermejo, Justo Lorenzo, Brenner, Hermann, Hoffmeister, Michael, Williams, Ann C., Relton, Caroline L.
Publicado 2021