Quantifying cellular dynamics in mice using a novel fluorescent division reporter system

por Lukas, Eva, Hogan, Thea, Williams, Cayman, Seddon, Benedict, Yates, Andrew J.
Publicado 2023

Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis

por Williams, Cayman, Kennedy, Alan, Robinson, Maximillian A., Lloyd, Christopher, Dovedi, Simon J., Sansom, David M.
Publicado 2022

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

por Glinos, Dafni A., Soskic, Blagoje, Williams, Cayman, Kennedy, Alan, Jostins, Luke, Sansom, David M., Trynka, Gosia
Publicado 2020

The CTLA‐4 immune checkpoint protein regulates PD‐L1:PD‐1 interaction via transendocytosis of its ligand CD80

por Kennedy, Alan, Robinson, Maximillian A, Hinze, Claudia, Waters, Erin, Williams, Cayman, Halliday, Neil, Dovedi, Simon, Sansom, David M
Publicado 2023

Regulation of CTLA‐4 recycling by LRBA and Rab11

por Janman, Daniel, Hinze, Claudia, Kennedy, Alan, Halliday, Neil, Waters, Erin, Williams, Cayman, Rowshanravan, Behzad, Hou, Tie Zheng, Minogue, Shane, Qureshi, Omar S., Sansom, David M.
Publicado 2021

CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis

por Soskic, Blagoje, Jeffery, Louisa E., Kennedy, Alan, Gardner, David H., Hou, Tie Zheng, Halliday, Neil, Williams, Cayman, Janman, Daniel, Rowshanravan, Behzad, Hirschfield, Gideon M., Sansom, David M.
Publicado 2021

CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4

por Halliday, Neil, Williams, Cayman, Kennedy, Alan, Waters, Erin, Pesenacker, Anne M., Soskic, Blagoje, Hinze, Claudia, Hou, Tie Zheng, Rowshanravan, Behzad, Janman, Daniel, Walker, Lucy S. K., Sansom, David M.
Publicado 2020

Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

por Kennedy, Alan, Waters, Erin, Rowshanravan, Behzad, Hinze, Claudia, Williams, Cayman, Janman, Daniel, Fox, Thomas A., Booth, Claire, Pesenacker, Anne M., Halliday, Neil, Soskic, Blagoje, Kaur, Satdip, Qureshi, Omar S., Morris, Emma C., Ikemizu, Shinji, Paluch, Christopher, Huo, Jiandong, Davis, Simon J., Boucrot, Emmanuel, Walker, Lucy S. K., Sansom, David M.
Publicado 2022