A Novel Method for Gene-Specific Enhancement of Protein Translation by Targeting 5’UTRs of Selected Tumor Suppressors

por Master, Adam, Wójcicka, Anna, Giżewska, Kamilla, Popławski, Piotr, Williams, Graham R., Nauman, Alicja
Publicado 2016

Characterization of skeletal phenotypes of TRα1(PV) and TRβ(PV) mutant mice: implications for tissue thyroid status and T3 target gene expression

por O'Shea, Patrick J., Bassett, J.H. Duncan, Cheng, Sheue-yann, Williams, Graham R.
Publicado 2006

Rapid phenotyping of knockout mice to identify genetic determinants of bone strength

por Freudenthal, Bernard, Logan, John, Croucher, Peter I, Williams, Graham R, Bassett, J H Duncan
Publicado 2016

Effect of selenium supplementation on musculoskeletal health in older women: a randomised, double-blind, placebo-controlled trial

por Walsh, Jennifer S, Jacques, Richard M, Schomburg, Lutz, Hill, Tom R, Mathers, John C, Williams, Graham R, Eastell, Richard
Publicado 2021

Iodothyronine deiodinase enzyme activities in bone

por Williams, Allan J., Robson, Helen, Kester, Monique H.A., van Leeuwen, Johannes P.T.M., Shalet, Stephen M., Visser, Theo J., Williams, Graham R.
Publicado 2008

Thyroid Hormone Receptor α Mutation Causes a Severe and Thyroxine-Resistant Skeletal Dysplasia in Female Mice

por Bassett, J. H. Duncan, Boyde, Alan, Zikmund, Tomas, Evans, Holly, Croucher, Peter I., Zhu, Xuguang, Park, Jeong Won, Cheng, Sheue-yann, Williams, Graham R.
Publicado 2014

Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha

por Freudenthal, Bernard, Shetty, Samiksha, Butterfield, Natalie C., Logan, John G., Han, Cho Rong, Zhu, Xuguang, Astapova, Inna, Hollenberg, Anthony N., Cheng, Sheue-Yann, Bassett, J.H. Duncan, Williams, Graham R.
Publicado 2019

Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice

por Loisay, Léa, Komla-Ebri, Davide, Morice, Anne, Heuzé, Yann, Viaut, Camille, de La Seiglière, Amélie, Kaci, Nabil, Chan, Danny, Lamouroux, Audrey, Baujat, Geneviève, Bassett, J.H. Duncan, Williams, Graham R., Legeai-Mallet, Laurence
Publicado 2023

Thyrostimulin Regulates Osteoblastic Bone Formation During Early Skeletal Development

por Bassett, J. H. Duncan, van der Spek, Anne, Logan, John G., Gogakos, Apostolos, Bagchi-Chakraborty, Jayashree, Murphy, Elaine, van Zeijl, Clementine, Down, Jenny, Croucher, Peter I., Boyde, Alan, Boelen, Anita, Williams, Graham R.
Publicado 2015

PYY is a negative regulator of bone mass and strength

por Leitch, Victoria D., Brassill, Mary Jane, Rahman, Sofia, Butterfield, Natalie C., Ma, Pattara, Logan, John G., Boyde, Alan, Evans, Holly, Croucher, Peter I., Batterham, Rachel L., Williams, Graham R., Bassett, J.H. Duncan
Publicado 2019

A trans-eQTL network regulates osteoclast multinucleation and bone mass

por Pereira, Marie, Ko, Jeong-Hun, Logan, John, Protheroe, Hayley, Kim, Kee-Beom, Tan, Amelia Li Min, Croucher, Peter I, Park, Kwon-Sik, Rotival, Maxime, Petretto, Enrico, Bassett, JH Duncan, Williams, Graham R, Behmoaras, Jacques
Publicado 2020

An Essential Physiological Role for MCT8 in Bone in Male Mice

por Leitch, Victoria D., Di Cosmo, Caterina, Liao, Xiao-Hui, O’Boy, Sam, Galliford, Thomas M., Evans, Holly, Croucher, Peter I., Boyde, Alan, Dumitrescu, Alexandra, Weiss, Roy E., Refetoff, Samuel, Williams, Graham R., Bassett, J. H. Duncan
Publicado 2017

Rapid-Throughput Skeletal Phenotyping of 100 Knockout Mice Identifies 9 New Genes That Determine Bone Strength

por Bassett, J. H. Duncan, Gogakos, Apostolos, White, Jacqueline K., Evans, Holly, Jacques, Richard M., van der Spek, Anne H., Ramirez-Solis, Ramiro, Ryder, Edward, Sunter, David, Boyde, Alan, Campbell, Michael J., Croucher, Peter I., Williams, Graham R.
Publicado 2012

A molecular quantitative trait locus map for osteoarthritis

por Steinberg, Julia, Southam, Lorraine, Roumeliotis, Theodoros I., Clark, Matthew J., Jayasuriya, Raveen L., Swift, Diane, Shah, Karan M., Butterfield, Natalie C., Brooks, Roger A., McCaskie, Andrew W., Bassett, J. H. Duncan, Williams, Graham R., Choudhary, Jyoti S., Wilkinson, J. Mark, Zeggini, Eleftheria
Publicado 2021

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight

por Hameed, Saira, Patterson, Michael, Dhillo, Waljit S., Rahman, Sofia A., Ma, Yue, Holton, Christopher, Gogakos, Apostolos, Yeo, Giles S.H., Lam, Brian Y.H., Polex-Wolf, Joseph, Fenske, Wiebke, Bell, Jimmy, Anastasovska, Jelena, Samarut, Jacques, Bloom, Stephen R., Bassett, J.H. Duncan, Williams, Graham R., Gardiner, James V.
Publicado 2017

An ARHGAP25 variant links aberrant Rac1 function to early‐onset skeletal fragility

por Mäkitie, Riikka E., Henning, Petra, Jiu, Yaming, Kämpe, Anders, Kogan, Konstantin, Costantini, Alice, Välimäki, Ville‐Valtteri, Medina‐Gomez, Carolina, Pekkinen, Minna, Salusky, Isidro B., Schalin‐Jäntti, Camilla, Haanpää, Maria K., Rivadeneira, Fernando, Bassett, John H. Duncan, Williams, Graham R., Lerner, Ulf H., Pereira, Renata C., Lappalainen, Pekka, Mäkitie, Outi
Publicado 2021

A Roadmap to Gene Discoveries and Novel Therapies in Monogenic Low and High Bone Mass Disorders

por Formosa, Melissa M., Bergen, Dylan J. M., Gregson, Celia L., Maurizi, Antonio, Kämpe, Anders, Garcia-Giralt, Natalia, Zhou, Wei, Grinberg, Daniel, Ovejero Crespo, Diana, Zillikens, M. Carola, Williams, Graham R., Bassett, J. H. Duncan, Brandi, Maria Luisa, Sangiorgi, Luca, Balcells, Susanna, Högler, Wolfgang, Van Hul, Wim, Mäkitie, Outi
Publicado 2021

Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy...

por Tobias, Jonathan H., Duncan, Emma L., Kague, Erika, Hammond, Chrissy L., Gregson, Celia L., Bassett, Duncan, Williams, Graham R., Min, Josine L., Gaunt, Tom R., Karasik, David, Ohlsson, Claes, Rivadeneira, Fernando, Edwards, James R., Hannan, Fadil M., Kemp, John P., Gilbert, Sophie J., Alonso, Nerea, Hassan, Neelam, Compston, Juliet E., Ralston, Stuart H.
Publicado 2021

Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes

por Gregson, Celia L., Newell, Felicity, Leo, Paul J., Clark, Graeme R., Paternoster, Lavinia, Marshall, Mhairi, Forgetta, Vincenzo, Morris, John A., Ge, Bing, Bao, Xiao, Duncan Bassett, J.H., Williams, Graham R., Youlten, Scott E., Croucher, Peter I., Davey Smith, George, Evans, David M., Kemp, John P., Brown, Matthew A., Tobias, Jon H., Duncan, Emma L.
Publicado 2018

Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling

por Rauner, Martina, Baschant, Ulrike, Roetto, Antonella, Pellegrino, Rosa Maria, Rother, Sandra, Salbach-Hirsch, Juliane, Weidner, Heike, Hintze, Vera, Campbell, Graeme, Petzold, Andreas, Lemaitre, Regis, Henry, Ian, Bellido, Teresita, Theurl, Igor, Altamura, Sandro, Colucci, Silvia, Muckenthaler, Martina U., Schett, Georg, Komla Ebri, Davide, Bassett, J. H. Duncan, Williams, Graham R., Platzbecker, Uwe, Hofbauer, Lorenz C.
Publicado 2019