New Model Systems and the Development of Targeted Therapies for the Treatment of Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors

por Williams, Kyle B., Largaespada, David A.
Publicado 2020

Evidence of a Bacterial Receptor for Lysozyme: Binding of Lysozyme to the Anti-σ Factor RsiV Controls Activation of the ECF σ Factor σ(V)

por Hastie, Jessica L., Williams, Kyle B., Sepúlveda, Carolina, Houtman, Jon C., Forest, Katrina T., Ellermeier, Craig D.
Publicado 2014

The Anti-sigma Factor RsiV Is a Bacterial Receptor for Lysozyme: Co-crystal Structure Determination and Demonstration That Binding of Lysozyme to RsiV Is Required for σ(V) Activati...

por Hastie, Jessica L., Williams, Kyle B., Bohr, Lindsey L., Houtman, Jon C., Gakhar, Lokesh, Ellermeier, Craig D.
Publicado 2016

Perinatal folate levels do not influence tumor latency or multiplicity in a model of NF1 associated plexiform-like neurofibromas

por Williams, Kyle B., Marley, Andrew R., Tibbitts, Justin, Moertel, Christopher L., Johnson, Kimberly J., Linden, Michael A., Largaespada, David A., Marcotte, Erin L.
Publicado 2023

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1

por Isakson, Sara H., Rizzardi, Anthony E., Coutts, Alexander W., Carlson, Daniel F., Kirstein, Mark N., Fisher, James, Vitte, Jeremie, Williams, Kyle B., Pluhar, G. Elizabeth, Dahiya, Sonika, Widemann, Brigitte C., Dombi, Eva, Rizvi, Tilat, Ratner, Nancy, Messiaen, Ludwine, Stemmer-Rachamimov, Anat O., Fahrenkrug, Scott C., Gutmann, David H., Giovannini, Marco, Moertel, Christopher L., Largaespada, David A., Watson, Adrienne L.
Publicado 2018

Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology

por Larsson, Alex T, Bhatia, Himanshi, Calizo, Ana, Pollard, Kai, Zhang, Xiaochun, Conniff, Eric, Tibbitts, Justin F, Rono, Elizabeth, Cummins, Katherine, Osum, Sara H, Williams, Kyle B, Crampton, Alexandra L, Jubenville, Tyler, Schefer, Daniel, Yang, Kuangying, Lyu, Yang, Pino, James C, Bade, Jessica, Gross, John M, Lisok, Alla, Dehner, Carina A, Chrisinger, John S A, He, Kevin, Gosline, Sara J C, Pratilas, Christine A, Largaespada, David A, Wood, David K, Hirbe, Angela C
Publicado 2023