Characterization and Sequence Mapping of Large RNA and mRNA Therapeutics Using Mass Spectrometry

por Vanhinsbergh, Christina J., Criscuolo, Angela, Sutton, Jennifer N., Murphy, Keeley, Williamson, Andrew J. K., Cook, Ken, Dickman, Mark J.
Publicado 2022

THOC5 controls 3′end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100)

por Tran, Doan Duy Hai, Saran, Shashank, Williamson, Andrew J.K., Pierce, Andrew, Dittrich-Breiholz, Oliver, Wiehlmann, Lutz, Koch, Alexandra, Whetton, Anthony D., Tamura, Teruko
Publicado 2014

BCR-ABL Affects STAT5A and STAT5B Differentially

por Schaller-Schönitz, Michael, Barzan, David, Williamson, Andrew J. K., Griffiths, John R., Dallmann, Iris, Battmer, Karin, Ganser, Arnold, Whetton, Anthony D., Scherr, Michaela, Eder, Matthias
Publicado 2014

MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5

por Whetton, Anthony D., Azmi, Norhaida Che, Pearson, Stella, Jaworska, Ewa, Zhang, Liqun, Blance, Rognvald, Kendall, Alexandra C., Nicolaou, Anna, Taylor, Samuel, Williamson, Andrew J.K., Pierce, Andrew
Publicado 2016

The Methyltransferase WBSCR22/Merm1 Enhances Glucocorticoid Receptor Function and Is Regulated in Lung Inflammation and Cancer

por Jangani, Maryam, Poolman, Toryn M., Matthews, Laura, Yang, Nan, Farrow, Stuart N., Berry, Andrew, Hanley, Neil, Williamson, Andrew J. K., Whetton, Anthony D., Donn, Rachelle, Ray, David W.
Publicado 2014

Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production

por Morgan, David J., Poolman, Toryn M., Williamson, Andrew J. K., Wang, Zichen, Clark, Neil R., Ma’ayan, Avi, Whetton, Anthony D., Brass, Andrew, Matthews, Laura C., Ray, David W.
Publicado 2016

Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells

por Bulut-Karslioglu, Aydan, Jin, Hu, Kim, Yun-Kyo, Cho, Brandon, Guzman-Ayala, Marcela, Williamson, Andrew J. K., Hejna, Miroslav, Stötzel, Maximilian, Whetton, Anthony D., Song, Jun S., Ramalho-Santos, Miguel
Publicado 2021

Comparative Quantification of the Surfaceome of Human Multipotent Mesenchymal Progenitor Cells

por Holley, Rebecca J., Tai, Guangping, Williamson, Andrew J.K., Taylor, Samuel, Cain, Stuart A., Richardson, Stephen M., Merry, Catherine L.R., Whetton, Anthony D., Kielty, Cay M., Canfield, Ann E.
Publicado 2015

Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value

por Walker, Michael J., Zhou, Cong, Backen, Alison, Pernemalm, Maria, Williamson, Andrew J.K., Priest, Lynsey J.C., Koh, Pek, Faivre-Finn, Corinne, Blackhall, Fiona H., Dive, Caroline, Whetton, Anthony D.
Publicado 2015

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids

por Dutta, Anindita, Potier, David N., Walker, Michael J., Gray, Oliver J., Parker, Catriona, Holland, Mark, Williamson, Andrew J.K., Pierce, Andrew, Unwin, Richard D., Krishnan, Shekhar, Saha, Vaskar, Whetton, Anthony D.
Publicado 2016

Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia

por Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle, Baker, Sarah, Gilkes, Amanda F., Knapper, Steven, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L., Tonks, Alex
Publicado 2019

HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block

por Maiques-Diaz, Alba, Nicosia, Luciano, Basma, Naseer J., Romero-Camarero, Isabel, Camera, Francesco, Spencer, Gary J., Amaral, Fabio M. R., Simeoni, Fabrizio, Wingelhofer, Bettina, Williamson, Andrew J. K., Pierce, Andrew, Whetton, Anthony D., Somervaille, Tim C. P.
Publicado 2022

Protein Z: A putative novel biomarker for early detection of ovarian cancer

por Russell, Matthew R., Walker, Michael J., Williamson, Andrew J. K., Gentry‐Maharaj, Aleksandra, Ryan, Andy, Kalsi, Jatinderpal, Skates, Steven, D'Amato, Alfonsina, Dive, Caroline, Pernemalm, Maria, Humphryes, Phillip C., Fourkala, Evangelia‐Ourania, Whetton, Anthony D., Menon, Usha, Jacobs, Ian, Graham, Robert L.J.
Publicado 2016

S124: PHOSPHOPROTEOMICS ACCURATELY PREDICTS RESPONSES TO MIDOSTAURIN PLUS CHEMOTHERAPY IN TWO INDEPENDENT COHORTS OF FLT3 MUTANT-POSITIVE ACUTE MYELOID LEUKAEMIA

por Dokal, Arran, Borek, Weronika E., Nobre, Luis, Federico Pedicona, Salvatore, Wrench, Bela, Gallipoli, Paolo, Arruda, Andrea, Campbell, Amy E., Nawaz, Nazrath, Ferguson, Harriet R., Perkins, David N., Moreno-Cardoso, Pedro, Thompson, Andrew, Williamson, Andrew J.K., Minden, Mark D., Gribben, John G., Britton, David J., Cutillas, Pedro R.
Publicado 2023

EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association

por Paredes, Roberto, Schneider, Marion, Stevens, Adam, White, Daniel J, Williamson, Andrew J K, Muter, Joanne, Pearson, Stella, Kelly, James R, Connors, Kathleen, Wiseman, Daniel H, Chadwick, John A, Löffler, Harald, Teng, Hsiang Ying, Lovell, Simon, Unwin, Richard, van de Vrugt, Henri J, Smith, Helen, Kustikova, Olga, Schambach, Axel, Somervaille, Tim C P, Pierce, Andrew, Whetton, Anthony D, Meyer, Stefan
Publicado 2018

Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption

por Meyer, Stefan, Stevens, Adam, Paredes, Roberto, Schneider, Marion, Walker, Michael J, Williamson, Andrew J K, Gonzalez-Sanchez, Maria-Belen, Smetsers, Stephanie, Dalal, Vineet, Teng, Hsiang Ying, White, Daniel J, Taylor, Sam, Muter, Joanne, Pierce, Andrew, de Leonibus, Chiara, Rockx, Davy A P, Rooimans, Martin A, Spooncer, Elaine, Stauffer, Stacey, Biswas, Kajal, Godthelp, Barbara, Dorsman, Josephine, Clayton, Peter E, Sharan, Shyam K, Whetton, Anthony D
Publicado 2017