Whole-genome and transcriptome analysis of advanced adrenocortical cancer highlights multiple alterations affecting epigenome and DNA repair pathways

por Lavoie, Jean-Michel, Csizmok, Veronika, Williamson, Laura M., Culibrk, Luka, Wang, Gang, Marra, Marco A., Laskin, Janessa, Jones, Steven J.M., Renouf, Daniel J., Kollmannsberger, Christian K.
Publicado 2022

TMBur: a distributable tumor mutation burden approach for whole genome sequencing

por Titmuss, Emma, Corbett, Richard D., Davidson, Scott, Abbasi, Sanna, Williamson, Laura M., Pleasance, Erin D., Shlien, Adam, Renouf, Daniel J., Jones, Steven J. M., Laskin, Janessa, Marra, Marco A.
Publicado 2022

Fluorouracil sensitivity in a head and neck squamous cell carcinoma with a somatic DPYD structural variant

por Majounie, Elisa, Wee, Kathleen, Williamson, Laura M., Jones, Martin R., Pleasance, Erin, Lim, Howard J., Ho, Cheryl, Renouf, Daniel J., Yip, Stephen, Jones, Steven J.M., Marra, Marco A., Laskin, Janessa
Publicado 2020

Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers

por Romero, Joan Miguel, Titmuss, Emma, Wang, Yifan, Vafiadis, James, Pacis, Alain, Jang, Gun Ho, Zhang, Amy, Golesworthy, Bryn, Lenko, Tatiana, Williamson, Laura M., Grünwald, Barbara, O’Kane, Grainne M., Jones, Steven J. M., Marra, Marco. A., Wilson, Julie M., Gallinger, Steven, Laskin, Janessa, Zogopoulos, George
Publicado 2023

Genomic characterization of a well-differentiated grade 3 pancreatic neuroendocrine tumor

por Williamson, Laura M., Steel, Michael, Grewal, Jasleen K., Thibodeau, My Lihn, Zhao, Eric Y., Loree, Jonathan M., Yang, Kevin C., Gorski, Sharon M., Mungall, Andrew J., Mungall, Karen L., Moore, Richard A., Marra, Marco A., Laskin, Janessa, Renouf, Daniel J., Schaeffer, David F., Jones, Steven J.M.
Publicado 2019

Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration

por Tsang, Erica S., Csizmok, Veronika, Williamson, Laura M., Pleasance, Erin, Topham, James T., Karasinska, Joanna M., Titmuss, Emma, Schrader, Intan, Yip, Stephen, Tessier-Cloutier, Basile, Mungall, Karen, Ng, Tony, Sun, Sophie, Lim, Howard J., Loree, Jonathan M., Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Publicado 2023

Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury

por Williamson, Laura M., Rive, Craig M., Di Francesco, Daniela, Titmuss, Emma, Chun, Hye-Jung E., Brown, Scott D., Milne, Katy, Pleasance, Erin, Lee, Anna F., Yip, Stephen, Rosenbaum, Daniel G., Hasselblatt, Martin, Johann, Pascal D., Kool, Marcel, Harvey, Melissa, Dix, David, Renouf, Daniel J., Holt, Robert A., Nelson, Brad H., Hirst, Martin, Jones, Steven J. M., Laskin, Janessa, Rassekh, Shahrad R., Deyell, Rebecca J., Marra, Marco A.
Publicado 2021

A platform for oncogenomic reporting and interpretation

por Reisle, Caralyn, Williamson, Laura M., Pleasance, Erin, Davies, Anna, Pellegrini, Brayden, Bleile, Dustin W., Mungall, Karen L., Chuah, Eric, Jones, Martin R., Ma, Yussanne, Lewis, Eleanor, Beckie, Isaac, Pham, David, Matiello Pletz, Raphael, Muhammadzadeh, Amir, Pierce, Brandon M., Li, Jacky, Stevenson, Ross, Wong, Hansen, Bailey, Lance, Reisle, Abbey, Douglas, Matthew, Bonakdar, Melika, Nelson, Jessica M. T., Grisdale, Cameron J., Krzywinski, Martin, Fisic, Ana, Mitchell, Teresa, Renouf, Daniel J., Yip, Stephen, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M.
Publicado 2022

Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma

por Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Publicado 2022