Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes

por Briney, Bryan S., Willis, Jordan R., Crowe, James E.
Publicado 2012

Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity

por Briney, Bryan S., Willis, Jordan R., Crowe, James E.
Publicado 2012

Maturation-Induced Cloaking of Neutralization Epitopes on HIV-1 Particles

por Joyner, Amanda S., Willis, Jordan R., Crowe, James E., Aiken, Christopher
Publicado 2011

Human Germline Antibody Gene Segments Encode Polyspecific Antibodies

por Willis, Jordan R., Briney, Bryan S., DeLuca, Samuel L., Crowe, James E., Meiler, Jens
Publicado 2013

Tissue-Specific Expressed Antibody Variable Gene Repertoires

por Briney, Bryan S., Willis, Jordan R., Finn, Jessica A., McKinney, Brett A., Crowe, James E.
Publicado 2014

Correction: Tissue-Specific Expressed Antibody Variable Gene Repertoires

por Briney, Bryan S., Willis, Jordan R., Finn, Jessica A., McKinney, Brett A., Crowe, James E.
Publicado 2020

Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints

por Finn, Jessica A., Koehler Leman, Julia, Willis, Jordan R., Cisneros, Alberto, Crowe, James E., Meiler, Jens
Publicado 2016

PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST

por Soto, Cinque, Finn, Jessica A., Willis, Jordan R., Day, Samuel B., Sinkovits, Robert S., Jones, Taylor, Schmitz, Samuel, Meiler, Jens, Branchizio, Andre, Crowe, James E.
Publicado 2020

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

por Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicado 2017

Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries

por Yuan, Tom Z., Garg, Pankaj, Wang, Linya, Willis, Jordan R., Kwan, Eric, Hernandez, Ana G Lujan, Tuscano, Emily, Sever, Emily N., Keane, Erica, Soto, Cinque, Mucker, Eric M., Fouch, Mallorie E., Davidson, Edgar, Doranz, Benjamin J., Kailasan, Shweta, Aman, M. Javad, Li, Haoyang, Hooper, Jay W., Saphire, Erica Ollmann, Crowe, James E., Liu, Qiang, Axelrod, Fumiko, Sato, Aaron K.
Publicado 2021

Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice

por Melzi, Eleonora, Willis, Jordan R., Ma, Krystal M., Lin, Ying-Cing, Kratochvil, Sven, Berndsen, Zachary T., Landais, Elise A., Kalyuzhniy, Oleksandr, Nair, Usha, Warner, John, Steichen, Jon M., Kalyuzhniy, Anton, Le, Amber, Pecetta, Simone, Perez, Manfredo, Kirsch, Kathrin, Weldon, Stephanie R., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Sok, Devin, Ward, Andrew B., Schief, William R., Batista, Facundo D.
Publicado 2022

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

por Willis, Jordan R., Berndsen, Zachary T., Ma, Krystal M., Steichen, Jon M., Schiffner, Torben, Landais, Elise, Liguori, Alessia, Kalyuzhniy, Oleksandr, Allen, Joel D., Baboo, Sabyasachi, Omorodion, Oluwarotimi, Diedrich, Jolene K., Hu, Xiaozhen, Georgeson, Erik, Phelps, Nicole, Eskandarzadeh, Saman, Groschel, Bettina, Kubitz, Michael, Adachi, Yumiko, Mullin, Tina-Marie, Alavi, Nushin B., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Wilson, Ian A., Yates, John R., Paulson, James C., Crispin, Max, Ward, Andrew B., Schief, William R.
Publicado 2022