Application of single-cell genomics in cancer: promise and challenges

por Wills, Quin F., Mead, Adam J.
Publicado 2015

A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells

por Yang, Yu Hsuan Carol, Wills, Quin F., Johnson, James D.
Publicado 2015

Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R

por McCarthy, Davis J, Campbell, Kieran R, Lun, Aaron T L, Wills, Quin F
Publicado 2017

Isoform-level gene expression patterns in single-cell RNA-sequencing data

por Vu, Trung Nghia, Wills, Quin F, Kalari, Krishna R, Niu, Nifang, Wang, Liewei, Pawitan, Yudi, Rantalainen, Mattias
Publicado 2018

Statistical approaches and software for clustering islet cell functional heterogeneity

por Wills, Quin F., Boothe, Tobias, Asadi, Ali, Ao, Ziliang, Warnock, Garth L., Kieffer, Timothy J., Johnson, James D.
Publicado 2016

Methods for qPCR gene expression profiling applied to 1440 lymphoblastoid single cells

por Livak, Kenneth J., Wills, Quin F., Tipping, Alex J., Datta, Krishnalekha, Mittal, Rowena, Goldson, Andrew J., Sexton, Darren W., Holmes, Chris C.
Publicado 2013

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer

por Athreya, Arjun P., Kalari, Krishna R., Cairns, Junmei, Gaglio, Alan J., Wills, Quin F., Niu, Nifang, Weinshilboum, Richard, Iyer, Ravishankar K., Wang, Liewei
Publicado 2017

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

por Herrera, Blanca M, Lockstone, Helen E, Taylor, Jennifer M, Wills, Quin F, Kaisaki, Pamela J, Barrett, Amy, Camps, Carme, Fernandez, Christina, Ragoussis, Jiannis, Gauguier, Dominique, McCarthy, Mark I, Lindgren, Cecilia M
Publicado 2009

MicroRNA Expression in Abdominal and Gluteal Adipose Tissue Is Associated with mRNA Expression Levels and Partly Genetically Driven

por Rantalainen, Mattias, Herrera, Blanca M., Nicholson, George, Bowden, Rory, Wills, Quin F., Min, Josine L., Neville, Matt J., Barrett, Amy, Allen, Maxine, Rayner, Nigel W., Fleckner, Jan, McCarthy, Mark I., Zondervan, Krina T., Karpe, Fredrik, Holmes, Chris C., Lindgren, Cecilia M.
Publicado 2011

The nature and nurture of cell heterogeneity: accounting for macrophage gene-environment interactions with single-cell RNA-Seq

por Wills, Quin F., Mellado-Gomez, Esther, Nolan, Rory, Warner, Damien, Sharma, Eshita, Broxholme, John, Wright, Benjamin, Lockstone, Helen, James, William, Lynch, Mark, Gonzales, Michael, West, Jay, Leyrat, Anne, Padilla-Parra, Sergi, Filippi, Sarah, Holmes, Chris, Moore, Michael D., Bowden, Rory
Publicado 2017

Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes

por Min, Josine L., Nicholson, George, Halgrimsdottir, Ingileif, Almstrup, Kristian, Petri, Andreas, Barrett, Amy, Travers, Mary, Rayner, Nigel W., Mägi, Reedik, Pettersson, Fredrik H., Broxholme, John, Neville, Matt J., Wills, Quin F., Cheeseman, Jane, Allen, Maxine, Holmes, Chris C., Spector, Tim D., Fleckner, Jan, McCarthy, Mark I., Karpe, Fredrik, Lindgren, Cecilia M., Zondervan, Krina T.
Publicado 2012