Targeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells

por Wilmore, Sarah, Rogers-Broadway, Karly-Rai, Taylor, Joe, Lemm, Elizabeth, Fell, Rachel, Stevenson, Freda K., Forconi, Francesco, Steele, Andrew J., Coldwell, Mark, Packham, Graham, Yeomans, Alison
Publicado 2021

B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells

por Taylor, Joe, Wilmore, Sarah, Marriot, Sophie, Rogers-Broadway, Karly-Rai, Fell, Rachel, Minton, Annabel R., Branch, Tom, Ashton-Key, Meg, Coldwell, Mark, Stevenson, Freda K., Forconi, Francesco, Steele, Andrew J., Packham, Graham, Yeomans, Alison
Publicado 2022

PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia...

por Yeomans, Alison, Lemm, Elizabeth, Wilmore, Sarah, Cavell, Breeze E., Valle-Argos, Beatriz, Krysov, Sergey, Hidalgo, Marina Sanchez, Leonard, Elodie, Willis, Anne E., Forconi, Francesco, Stevenson, Freda K., Steele, Andrew J., Coldwell, Mark J., Packham, Graham
Publicado 2016