A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases

por Southall, Stacey M., Cronin, Nora B., Wilson, Jon R.
Publicado 2014

Evolving Catalytic Properties of the MLL Family SET Domain

por Zhang, Ying, Mittal, Anshumali, Reid, James, Reich, Stephanie, Gamblin, Steven J., Wilson, Jon R.
Publicado 2015

The structure of the RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sites

por Mittal, Anshumali, Hobor, Fruzsina, Zhang, Ying, Martin, Stephen R, Gamblin, Steven J, Ramos, Andres, Wilson, Jon R
Publicado 2018

Foot-and-Mouth Disease Virus 2C Is a Hexameric AAA+ Protein with a Coordinated ATP Hydrolysis Mechanism

por Sweeney, Trevor R., Cisnetto, Valentina, Bose, Daniel, Bailey, Matthew, Wilson, Jon R., Zhang, Xiaodong, Belsham, Graham J., Curry, Stephen
Publicado 2010

Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells

por Willows, Robin, Sanders, Matthew J., Xiao, Bing, Patel, Bhakti R., Martin, Stephen R., Read, Jon, Wilson, Jon R., Hubbard, Julia, Gamblin, Steven J., Carling, David
Publicado 2017

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

por Justin, Neil, Zhang, Ying, Tarricone, Cataldo, Martin, Stephen R., Chen, Shuyang, Underwood, Elizabeth, De Marco, Valeria, Haire, Lesley F., Walker, Philip A., Reinberg, Danny, Wilson, Jon R., Gamblin, Steven J.
Publicado 2016

G-tract RNA removes Polycomb Repressive Complex 2 from genes

por Beltran, Manuel, Tavares, Manuel, Justin, Neil, Khandelwal, Garima, Ambrose, John, Foster, Benjamin M., Worlock, Kaylee B., Tvardovskiy, Andrey, Kunzelmann, Simone, Herrero, Javier, Bartke, Till, Gamblin, Steven J., Wilson, Jon R., Jenner, Richard G.
Publicado 2019

Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205),...

por Vaswani, Rishi G., Gehling, Victor S., Dakin, Les A., Cook, Andrew S., Nasveschuk, Christopher G., Duplessis, Martin, Iyer, Priyadarshini, Balasubramanian, Srividya, Zhao, Feng, Good, Andrew C., Campbell, Robert, Lee, Christina, Cantone, Nico, Cummings, Richard T., Normant, Emmanuel, Bellon, Steven F., Albrecht, Brian K., Harmange, Jean-Christophe, Trojer, Patrick, Audia, James E., Zhang, Ying, Justin, Neil, Chen, Shuyang, Wilson, Jon R., Gamblin, Steven J.
Publicado 2016