The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic...

por Manoharan, Christine, Wilson, Marieangela C., Sessions, Richard B., Halestrap, Andrew P.
Publicado 2006

Studies on the DIDS-binding Site of Monocarboxylate Transporter 1 Suggest a Homology Model of the Open Conformation and a Plausible Translocation Cycle

por Wilson, Marieangela C., Meredith, David, Bunnun, Chotirote, Sessions, Richard B., Halestrap, Andrew P.
Publicado 2009

The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein

por Ovens, Matthew J., Manoharan, Christine, Wilson, Marieangela C., Murray, Clarey M., Halestrap, Andrew P.
Publicado 2010

AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7–10

por Ovens, Matthew J., Davies, Andrew J., Wilson, Marieangela C., Murray, Clare M., Halestrap, Andrew P.
Publicado 2010

Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro

por Trakarnsanga, Kongtana, Wilson, Marieangela C., Heesom, Kate J., Andrienko, Tatyana N., Srisawat, Chatchawan, Frayne, Jan
Publicado 2018

Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton

por Zuccala, Elizabeth S., Satchwell, Timothy J., Angrisano, Fiona, Tan, Yan Hong, Wilson, Marieangela C., Heesom, Kate J., Baum, Jake
Publicado 2016

The Neuroplastin Adhesion Molecules Are Accessory Proteins That Chaperone the Monocarboxylate Transporter MCT2 to the Neuronal Cell Surface

por Wilson, Marieangela C., Kraus, Michaela, Marzban, Hassan, Sarna, Justyna R., Wang, Yisong, Hawkes, Richard, Halestrap, Andrew P., Beesley, Philip W.
Publicado 2013

MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera

por Tipgomut, Chartsiam, Khuhapinant, Archrob, Wilson, Marieangela C., Poldee, Saiphon, Heesom, Kate J., Metheetrairut, Chanatip, Sripichai, Orapan, Mitrpant, Chalermchai, Frayne, Jan, Trakarnsanga, Kongtana
Publicado 2021

Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia

por Chiriches, Claudia, Khan, Dilawar, Wieske, Maria, Guillen, Nathalie, Rokicki, Michal, Guy, Carol, Wilson, Marieangela, Heesom, Kate J., Ottmann, Oliver Gerhard, Ruthardt, Martin
Publicado 2022

Qualitative and Quantitative Comparison of the Proteome of Erythroid Cells Differentiated from Human iPSCs and Adult Erythroid Cells by Multiplex TMT Labelling and NanoLC-MS/MS

por Trakarnsanga, Kongtana, Wilson, Marieangela C., Griffiths, Rebecca E., Toye, Ashley M., Carpenter, Lee, Heesom, Kate J., Parsons, Steve F., Anstee, David J., Frayne, Jan
Publicado 2014

An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells

por Trakarnsanga, Kongtana, Griffiths, Rebecca E., Wilson, Marieangela C., Blair, Allison, Satchwell, Timothy J., Meinders, Marjolein, Cogan, Nicola, Kupzig, Sabine, Kurita, Ryo, Nakamura, Yukio, Toye, Ashley M., Anstee, David J., Frayne, Jan
Publicado 2017

Bicuspid Aortic Valve Alters Aortic Protein Expression Profile in Neonatal Coarctation Patients

por Skeffington, Katie L., Bond, Andrew R., Abdul-Ghani, Safa, Iacobazzi, Dominga, Kang, Sok-Leng, Heesom, Kate J., Wilson, Marieangela C., Ghorbel, Mohamed, Stoica, Serban, Martin, Robin, Suleiman, M. Saadeh, Caputo, Massimo
Publicado 2019

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells

por Morgan, Rhys G., Ridsdale, Jenna, Payne, Megan, Heesom, Kate J., Wilson, Marieangela C., Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C., Blair, Allison, Waterman, Marian L., Tonks, Alex, Darley, Richard L.
Publicado 2019

Changes in inflammation and oxidative stress signalling pathways in coarcted aorta triggered by bicuspid aortic valve and growth in young children

por Skeffington, Katie L., Bond, Andrew R., Bigotti, M. Giulia, AbdulGhani, Safa, Iacobazzi, Dominga, Kang, Sok-Leng, Heesom, Kate J., Wilson, Marieangela C., Stoica, Serban, Martin, Robin, Caputo, Massimo, Suleiman, M. Saadeh, Ghorbel, Mohamed T.
Publicado 2020

Human cellular model systems of β-thalassemia enable in-depth analysis of disease phenotype

por Daniels, Deborah E., Ferrer-Vicens, Ivan, Hawksworth, Joseph, Andrienko, Tatyana N., Finnie, Elizabeth M., Bretherton, Natalie S., Ferguson, Daniel C. J., Oliveira, A. Sofia. F., Szeto, Jenn-Yeu A., Wilson, Marieangela C., Brewin, John N., Frayne, Jan
Publicado 2023

Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editing

por Hawksworth, Joseph, Satchwell, Timothy J, Meinders, Marjolein, Daniels, Deborah E, Regan, Fiona, Thornton, Nicole M, Wilson, Marieangela C, Dobbe, Johannes GG, Streekstra, Geert J, Trakarnsanga, Kongtana, Heesom, Kate J, Anstee, David J, Frayne, Jan, Toye, Ashley M
Publicado 2018

Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation

por Trakarnsanga, Kongtana, Ferguson, Daniel, Daniels, Deborah E., Griffiths, Rebecca E., Wilson, Marieangela C., Mordue, Kathryn E., Gartner, Abi, Andrienko, Tatyana N., Calvert, Annabel, Condie, Alison, McCahill, Angela, Mountford, Joanne C., Toye, Ashley M., Anstee, David J., Frayne, Jan
Publicado 2019

Characterization and evolutionary origin of novel C2H2 zinc finger protein (ZNF648) required for both erythroid and megakaryocyte differentiation in humans

por Ferguson, Daniel C. J., Mokim, Juraidah Haji, Meinders, Marjolein, Moody, Edmund R. R., Williams, Tom A., Cooke, Sarah, Trakarnsanga, Kongtana, Daniels, Deborah E., Ferrer-Vicens, Ivan, Shoemark, Deborah, Tipgomut, Chartsiam, Macinnes, Katherine A., Wilson, Marieangela C., Singleton, Belinda K., Frayne, Jan
Publicado 2020

Reproducible immortalization of erythroblasts from multiple stem cell sources provides approach for sustainable RBC therapeutics

por Daniels, Deborah E., Ferguson, Daniel C.J., Griffiths, Rebecca E., Trakarnsanga, Kongtana, Cogan, Nicola, MacInnes, Katherine A., Mordue, Kathryn E., Andrienko, Tatyana, Ferrer-Vicens, Ivan, Ramos Jiménez, Daniel, Lewis, Phillip A., Wilson, Marieangela C., Canham, Maurice A., Kurita, Ryo, Nakamura, Yukio, Anstee, David J., Frayne, Jan
Publicado 2021

A role for NPY-NPY2R signaling in albuminuric kidney disease

por Lay, Abigail C., Barrington, A. Fern, Hurcombe, Jenny A., Ramnath, Raina D., Graham, Mark, Lewis, Philip A., Wilson, Marieangela C., Heesom, Kate J., Butler, Matthew J., Perrett, Rebecca M., Neal, Chris R., Herbert, Eleanor, Mountjoy, Edward, Atan, Denize, Nair, Viji, Ju, Wenjun, Nelson, Robert G., Kretzler, Matthias, Satchell, Simon C., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.
Publicado 2020