Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex

por Winkler, G. Sebastiaan, Balacco, Dario L.
Publicado 2013

The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4–Not nuclease module

por Maryati, Maryati, Airhihen, Blessing, Winkler, G. Sebastiaan
Publicado 2015

The Anti-Proliferative Activity of BTG/TOB Proteins Is Mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) Deadenylase Subunits of the Ccr4-Not Complex

por Doidge, Rachel, Mittal, Saloni, Aslam, Akhmed, Winkler, G. Sebastiaan
Publicado 2012

DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4–Not complex

por Mulder, Klaas W., Winkler, G. Sebastiaan, Timmers, H. Th. Marc
Publicado 2005

The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4–Not complex contribute to the prevention of cell death and senescence

por Mittal, Saloni, Aslam, Akhmed, Doidge, Rachel, Medica, Rachel, Winkler, G. Sebastiaan
Publicado 2011

Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1

por Jadhav, Gopal P., Kaur, Ishwinder, Maryati, Maryati, Airhihen, Blessing, Fischer, Peter M., Winkler, G. Sebastiaan
Publicado 2015

Disruption of the Mammalian Ccr4–Not Complex Contributes to Transcription-Mediated Genome Instability

por Hagkarim, Nafiseh Chalabi, Hajkarim, Morteza Chalabi, Suzuki, Toru, Fujiwara, Toshinobu, Winkler, G. Sebastiaan, Stewart, Grant S., Grand, Roger J.
Publicado 2023

A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity

por Maryati, Maryati, Kaur, Ishwinder, Jadhav, Gopal P., Olotu-Umoren, Loyin, Oveh, Blessing, Hashmi, Lubna, Fischer, Peter M., Winkler, G. Sebastiaan
Publicado 2014

Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA

por Hage, Naim, Howard, Tina, Phillips, Chris, Brassington, Claire, Overman, Ross, Debreczeni, Judit, Gellert, Paul, Stolnik, Snow, Winkler, G. Sebastiaan, Falcone, Franco H.
Publicado 2015

Structural and binding characterization of the LacdiNAc-specific adhesin (LabA; HopD) exodomain from Helicobacter pylori

por Paraskevopoulou, Vasiliki, Schimpl, Marianne, Overman, Ross C., Stolnik, Snow, Chen, Yajie, Nguyen, Linh, Winkler, G. Sebastiaan, Gellert, Paul, Klassen, John S., Falcone, Franco H.
Publicado 2020

Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells

por Collins, Hilary M, Abdelghany, Magdy K, Messmer, Marie, Yue, Baigong, Deeves, Sian E, Kindle, Karin B, Mantelingu, Kempegowda, Aslam, Akhmed, Winkler, G Sebastiaan, Kundu, Tapas K, Heery, David M
Publicado 2013