Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes

por Hecht, Randy, Li, Yue-Sheng, Sun, Jeonghoon, Belouski, Ed, Hall, Michael, Hager, Todd, Yie, Junming, Wang, Wei, Winters, Dwight, Smith, Stephen, Spahr, Chris, Tam, Lei-Ting, Shen, Zhongnan, Stanislaus, Shanaka, Chinookoswong, Narumol, Lau, Yvonne, Sickmier, Allen, Michaels, Mark Leo, Boone, Thomas, Véniant, Murielle M., Xu, Jing
Publicado 2012

Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies

por Mock, Marissa, Jacobitz, Alex W., Langmead, Christopher James, Sudom, Athena, Yoo, Daniel, Humphreys, Sara C., Alday, Mai, Alekseychyk, Larysa, Angell, Nicolas, Bi, Vivian, Catterall, Hannah, Chen, Chen-Chun, Chou, Hui-Ting, Conner, Kip P., Cook, Kevin D., Correia, Ana R., Dykstra, Andrew, Ghimire-Rijal, Sudipa, Graham, Kevin, Grandsard, Peter, Huh, Joon, Hui, John O., Jain, Mani, Jann, Victoria, Jia, Lei, Johnstone, Sheree, Khanal, Neelam, Kolvenbach, Carl, Narhi, Linda, Padaki, Rupa, Pelegri-O’Day, Emma M., Qi, Wei, Razinkov, Vladimir, Rice, Austin J., Smith, Richard, Spahr, Christopher, Stevens, Jennitte, Sun, Yax, Thomas, Veena A., van Driesche, Sarah, Vernon, Robert, Wagner, Victoria, Walker, Kenneth W., Wei, Yangjie, Winters, Dwight, Yang, Melissa, Campuzano, Iain D. G.
Publicado 2023