Sharp kinking of a coiled-coil in MutS allows DNA binding and release

por Bhairosing-Kok, Doreth, Groothuizen, Flora S, Fish, Alexander, Dharadhar, Shreya, Winterwerp, Herrie H K, Sixma, Titia K
Publicado 2019

Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutS

por Lebbink, Joyce H. G., Fish, Alexander, Reumer, Annet, Natrajan, Ganesh, Winterwerp, Herrie H. K., Sixma, Titia K.
Publicado 2010

USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A

por Uckelmann, Michael, Densham, Ruth M., Baas, Roy, Winterwerp, Herrie H. K., Fish, Alexander, Sixma, Titia K., Morris, Joanna R.
Publicado 2018

Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation

por Groothuizen, Flora S., Fish, Alexander, Petoukhov, Maxim V., Reumer, Annet, Manelyte, Laura, Winterwerp, Herrie H. K., Marinus, Martin G., Lebbink, Joyce H. G., Svergun, Dmitri I., Friedhoff, Peter, Sixma, Titia K.
Publicado 2013

Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair

por Hermans, Nicolaas, Laffeber, Charlie, Cristovão, Michele, Artola-Borán, Mariela, Mardenborough, Yannicka, Ikpa, Pauline, Jaddoe, Aruna, Winterwerp, Herrie H.K., Wyman, Claire, Jiricny, Josef, Kanaar, Roland, Friedhoff, Peter, Lebbink, Joyce H.G.
Publicado 2016

The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair

por Mardenborough, Yannicka S N, Nitsenko, Katerina, Laffeber, Charlie, Duboc, Camille, Sahin, Enes, Quessada-Vial, Audrey, Winterwerp, Herrie H K, Sixma, Titia K, Kanaar, Roland, Friedhoff, Peter, Strick, Terence R, Lebbink, Joyce H G
Publicado 2019

Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS

por Monti, Maria Chiara, Cohen, Serge X., Fish, Alexander, Winterwerp, Herrie H. K., Barendregt, Arjan, Friedhoff, Peter, Perrakis, Anastassis, Heck, Albert J. R., Sixma, Titia K., van den Heuvel, Robert H. H., Lebbink, Joyce H. G.
Publicado 2011