Lineage selection and plasticity in the intestinal crypt

por Philpott, Anna, Winton, Douglas J
Publicado 2014

Metaplastic Cdx2-depleted cells can be very disruptive neighbors

por Lourenço, Filipe C., Winton, Douglas J.
Publicado 2018

Turning off the BCL-2 switch to prevent intestinal tumorigenesis

por van der Heijden, Maartje, Winton, Douglas J., Vermeulen, Louis
Publicado 2016

A historical analysis of herpes simplex virus promoter activation in vivo reveals distinct populations of latently infected neurones

por Proença, João T., Coleman, Heather M., Connor, Viv, Winton, Douglas J., Efstathiou, Stacey
Publicado 2008

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models

por Mieszczanek, Juliusz, van Tienen, Laurens M., Ibrahim, Ashraf E. K., Winton, Douglas J., Bienz, Mariann
Publicado 2019

Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing

por Thorsen, Ann-Sofie, Khamis, Doran, Kemp, Richard, Colombé, Mathilde, Lourenço, Filipe C., Morrissey, Edward, Winton, Douglas
Publicado 2021

Delta1 Expression, Cell Cycle Exit, and Commitment to a Specific Secretory Fate Coincide within a Few Hours in the Mouse Intestinal Stem Cell System

por Stamataki, Despina, Holder, Maxine, Hodgetts, Christine, Jeffery, Rosemary, Nye, Emma, Spencer-Dene, Bradley, Winton, Douglas J., Lewis, Julian
Publicado 2011

Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny

por Davis, Felicity M., Lloyd-Lewis, Bethan, Harris, Olivia B., Kozar, Sarah, Winton, Douglas J., Muresan, Leila, Watson, Christine J.
Publicado 2016

5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation

por Uribe-Lewis, Santiago, Carroll, Thomas, Menon, Suraj, Nicholson, Anna, Manasterski, Piotr J., Winton, Douglas J., Buczacki, Simon J. A., Murrell, Adele
Publicado 2020

Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

por Shorning, Boris Y., Zabkiewicz, Joanna, McCarthy, Afshan, Pearson, Helen B., Winton, Douglas J., Sansom, Owen J., Ashworth, Alan, Clarke, Alan R.
Publicado 2009

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

por Shorning, Boris Y., Zabkiewicz, Joanna, McCarthy, Afshan, Pearson, Helen B., Winton, Douglas J., Sansom, Owen J., Ashworth, Alan, Clarke, Alan R.
Publicado 2009

Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-Deficient Murine Epithelium

por Christopher, Joseph, Thorsen, Ann-Sofie, Abujudeh, Sam, Lourenço, Filipe C., Kemp, Richard, Potter, Paul K., Morrissey, Edward, Hazelwood, Lee, Winton, Douglas J.
Publicado 2019

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

por Shorning, Boris Y., Zabkiewicz, Joanna, McCarthy, Afshan, Pearson, Helen B., Winton, Douglas J., Sansom, Owen J., Ashworth, Alan, Clarke, Alan R.
Publicado 2019

Itraconazole targets cell cycle heterogeneity in colorectal cancer

por Buczacki, Simon J.A., Popova, Semiramis, Biggs, Emma, Koukorava, Chrysa, Buzzelli, Jon, Vermeulen, Louis, Hazelwood, Lee, Francies, Hayley, Garnett, Mathew J., Winton, Douglas J.
Publicado 2018

Characterization of a heat resistant ß-glucosidase as a new reporter in cells and mice

por McCutcheon, Susan C, Jones, Ken, Cumming, Sarah A, Kemp, Richard, Ireland-Zecchini, Heather, Saunders, John C, Houghton, Carol A, Howard, Louise A, Winton, Douglas J
Publicado 2010

Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration

por Tomic, Goran, Morrissey, Edward, Kozar, Sarah, Ben-Moshe, Shani, Hoyle, Alice, Azzarelli, Roberta, Kemp, Richard, Chilamakuri, Chandra Sekhar Reddy, Itzkovitz, Shalev, Philpott, Anna, Winton, Douglas J.
Publicado 2018

Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR

por Skoufou-Papoutsaki, Nefeli, Adler, Sam, D'Santos, Paula, Mannion, Liz, Mehmed, Shenay, Kemp, Richard, Smith, Amy, Perrone, Francesca, Nayak, Komal, Russell, Alasdair, Zilbauer, Matthias, Winton, Douglas J.
Publicado 2023

Isolation of Human Colon Stem Cells Using Surface Expression of PTK7

por Jung, Peter, Sommer, Christian, Barriga, Francisco M., Buczacki, Simon J., Hernando-Momblona, Xavier, Sevillano, Marta, Duran-Frigola, Miquel, Aloy, Patrick, Selbach, Matthias, Winton, Douglas J., Batlle, Eduard
Publicado 2015

Bcl-2 is a critical mediator of intestinal transformation

por van der Heijden, Maartje, Zimberlin, Cheryl D., Nicholson, Anna M., Colak, Selcuk, Kemp, Richard, Meijer, Sybren L., Medema, Jan Paul, Greten, Florian R., Jansen, Marnix, Winton, Douglas J., Vermeulen, Louis
Publicado 2016

Detection of colorectal dysplasia using fluorescently labelled lectins

por Kuo, Joe Chin-Hun, Ibrahim, Ashraf E. K., Dawson, Sarah, Parashar, Deepak, Howat, William J., Guttula, Kiran, Miller, Richard, Fearnhead, Nicola S., Winton, Douglas J., Neves, André A., Brindle, Kevin M.
Publicado 2016