A Prospective, Post-Market, Multicenter Trial (CHEETAH) Suggested TearCare(®) System as a Safe and Effective Blink-Assisted Eyelid Device for the Treatment of Dry Eye Disease

por Karpecki, Paul, Wirta, David, Osmanovic, Smajo, Dhamdhere, Kavita
Publicado 2020

Phase 2b, Randomized, 3-Month, Dose-Finding Study of Sepetaprost in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: The ANGEL Study

por Wirta, David L., Kuwayama, Yasuaki, Lu, Fenghe, Shao, Hui, Odani-Kawabata, Noriko
Publicado 2022

Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis: Results of a Prospective, Randomized, Vehicle-Controlled, Double-Masked, Pivotal Trial (Saturn-1)

por Yeu, Elizabeth, Wirta, David L., Karpecki, Paul, Baba, Stephanie N., Holdbrook, Mark
Publicado 2023

A Comparison of TearCare and Lipiflow Systems in Reducing Dry Eye Disease Symptoms Associated with Meibomian Gland Disease

por Holland, Edward J, Loh, Jennifer, Bloomenstein, Marc, Thompson, Vance, Wirta, David, Dhamdhere, Kavita
Publicado 2022

A Randomized Clinical Study (SEECASE) to Assess Efficacy, Safety, and Tolerability of NOV03 for Treatment of Dry Eye Disease

por Tauber, Joseph, Wirta, David L., Sall, Kenneth, Majmudar, Parag A., Willen, Daniela, Krösser, Sonja
Publicado 2021

Repository Corticotropin Injection (Acthar(®) Gel) for Refractory Severe Noninfectious Keratitis: Efficacy and Safety from a Phase 4, Multicenter, Open-Label Study

por Wirta, David, McLaurin, Eugene, Ousler, George, Liu, Jingyu, Kacmaz, R. Oktay, Grieco, Joseph
Publicado 2021

Two Randomized, Double-masked, Placebo-controlled Studies of the Local Anesthetic Effect of Articaine Ophthalmic Solution

por Gonzalez, Victor H, Wirta, David L, Uram, Martin, Schupp, Audrey, Widmann, Michelle, Novack, Gary D
Publicado 2023

Long-term safety evaluation of bimatoprost ophthalmic solution 0.03%: a pooled analysis of six double-masked, randomized, active-controlled clinical trials

por Wirta, David, VanDenburgh, Amanda M, Weng, Emily, Whitcup, Scott M, Kurstjens, Sef, Beddingfield, Frederick C
Publicado 2011

An evaluation of the safety and efficacy of bimatoprost for eyelash growth in pediatric subjects

por Borchert, Mark, Bruce, Suzanne, Wirta, David, Yoelin, Steven G, Lee, Sungwook, Mao, Cheri, VanDenburgh, Amanda
Publicado 2016

Noninferiority Study Comparing Latanoprost 0.005% Without Versus With Benzalkonium Chloride in Open-Angle Glaucoma or Ocular Hypertension

por Wirta, David, Malhotra, Ranjan, Peace, James, Shen Lee, Bridgitte, Mitchell, Brittany, Sall, Kenneth, McMenemy, Matthew
Publicado 2022

Pharmacokinetics and safety of olopatadine hydrochloride 0.77% in healthy subjects with asymptomatic eyes: data from 2 independent clinical studies

por Meier, Edward, Narvekar, Abhijit, Iyer, Ganesh R, DuBiner, Harvey B, Vutikullird, Apinya, Wirta, David, Sall, Kenneth
Publicado 2017

Association of Oxymetazoline Hydrochloride, 0.1%, Solution Administration With Visual Field in Acquired Ptosis: A Pooled Analysis of 2 Randomized Clinical Trials

por Slonim, Charles B., Foster, Shane, Jaros, Mark, Kannarr, Shane R., Korenfeld, Michael S., Smyth-Medina, Robert, Wirta, David L.
Publicado 2020

ONSET-1 Phase 2b Randomized Trial to Evaluate the Safety and Efficacy of OC-01 (Varenicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease

por Wirta, David, Torkildsen, Gail L., Boehmer, Blair, Hollander, David A., Bendert, Edward, Zeng, Lijuan, Ackermann, Michael, Nau, Jeffrey
Publicado 2022

Safety and Target Engagement of Complement C1q Inhibitor ANX007 in Neurodegenerative Eye Disease: Results from Phase I Studies in Glaucoma

por Sun, Yang, Wirta, David, Murahashi, Wendy, Mathur, Vidhu, Sankaranarayanan, Sethu, Taylor, Lori K., Yednock, Ted, Fong, Donald S., Goldberg, Jeffrey L.
Publicado 2023

Efficacy and Safety of a Water-Free Topical Cyclosporine, 0.1%, Solution for the Treatment of Moderate to Severe Dry Eye Disease: The ESSENCE-2 Randomized Clinical Trial

por Akpek, Esen K., Wirta, David L., Downing, Johnathon E., Tauber, Joseph, Sheppard, John D., Ciolino, Joseph B., Meides, Alice S., Krösser, Sonja
Publicado 2023

Rapid and Sustained Eyelid Elevation in Acquired Blepharoptosis with Oxymetazoline 0.1%: Randomized Phase 3 Trial Results

por Bacharach, Jason, Wirta, David L, Smyth-Medina, Robert, Korenfeld, Michael S, Kannarr, Shane R, Foster, Shane, J Jaros, Mark, Slonim, Charles B
Publicado 2021

Safety of Once-Daily Oxymetazoline HCl Ophthalmic Solution, 0.1% in Patients with Acquired Blepharoptosis: Results from Four Randomized, Double-Masked Clinical Trials

por Wirta, David L, Korenfeld, Michael S, Foster, Shane, Smyth-Medina, Robert, Bacharach, Jason, Kannarr, Shane R, Jaros, Mark J, Slonim, Charles B
Publicado 2021

Combinations of Pilocarpine and Oxymetazoline for the Pharmacological Treatment of Presbyopia: Two Randomized Phase 2 Studies

por Price, Francis W., Hom, Milton, Moshirfar, Majid, Evans, David, Liu, Haixia, Penzner, Jeff, Robinson, Michael R., Lee, Sungwook, Wirta, David L.
Publicado 2021

Safety and Efficacy of AGN-190584 in Individuals With Presbyopia: The GEMINI 1 Phase 3 Randomized Clinical Trial

por Waring, George O., Price, Francis W., Wirta, David, McCabe, Cathleen, Moshirfar, Majid, Guo, Qiang, Gore, Anu, Liu, Haixia, Safyan, Eleonora, Robinson, Michael R.
Publicado 2022

A Water-free 0.1% Cyclosporine A Solution for Treatment of Dry Eye Disease: Results of the Randomized Phase 2B/3 ESSENCE Study

por Sheppard, John D., Wirta, David L., McLaurin, Eugene, Boehmer, Blair E., Ciolino, Joseph B., Meides, Alice S., Schlüter, Thomas, Ousler, George W., Usner, Dale, Krösser, Sonja
Publicado 2021