Neuron Loss in Alzheimer’s Disease: Translation in Transgenic Mouse Models

por Wirths, Oliver, Zampar, Silvia
Publicado 2020

Chronic Memantine Treatment Ameliorates Behavioral Deficits, Neuron Loss, and Impaired Neurogenesis in a Model of Alzheimer’s Disease

por Stazi, Martina, Wirths, Oliver
Publicado 2020

Characterization of a Mouse Model of Alzheimer’s Disease Expressing Aβ4-42 and Human Mutant Tau

por Zampar, Silvia, Wirths, Oliver
Publicado 2021

Intracellular Accumulation of Amyloid-Beta – A Predictor for Synaptic Dysfunction and Neuron Loss in Alzheimer's Disease

por Bayer, Thomas A., Wirths, Oliver
Publicado 2010

Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease

por Wirths, Oliver, Bayer, Thomas A.
Publicado 2010

Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease

por Bayer, Thomas A., Wirths, Oliver
Publicado 2014

Loss of Hippocampal Calretinin and Parvalbumin Interneurons in the 5XFAD Mouse Model of Alzheimer’s Disease

por Giesers, Naomi K., Wirths, Oliver
Publicado 2020

Effects of Long-Term Environmental Enrichment on Anxiety, Memory, Hippocampal Plasticity and Overall Brain Gene Expression in C57BL6 Mice

por Hüttenrauch, Melanie, Salinas, Gabriela, Wirths, Oliver
Publicado 2016

A novel interface between the N-terminal and coiled-coil domain of STAT1 functions in an auto-inhibitory manner

por Remling, Linus, Gregus, Anke, Wirths, Oliver, Meyer, Thomas, Staab, Julia
Publicado 2023

Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal Aβ accumulation

por Christensen, Ditte Z., Huettenrauch, Melanie, Mitkovski, Miso, Pradier, Laurent, Wirths, Oliver
Publicado 2014

The Cannabinoid CB1/CB2 Agonist WIN55212.2 Promotes Oligodendrocyte Differentiation In Vitro and Neuroprotection During the Cuprizone‐Induced Central Nervous System Demyelination

por Tomas‐Roig, Jordi, Wirths, Oliver, Salinas‐Riester, Gabriela, Havemann‐Reinecke, Ursula
Publicado 2016

Physical Activity Ameliorates Impaired Hippocampal Neurogenesis in the Tg4-42 Mouse Model of Alzheimer’s Disease

por Gerberding, Anna-Lina, Zampar, Silvia, Stazi, Martina, Liebetanz, David, Wirths, Oliver
Publicado 2019

An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form

por Menon, Priyanka Rajeev, Staab, Julia, Gregus, Anke, Wirths, Oliver, Meyer, Thomas
Publicado 2022

A Combination of Caffeine Supplementation and Enriched Environment in an Alzheimer’s Disease Mouse Model

por Stazi, Martina, Zampar, Silvia, Klafki, Hans-Wolfgang, Meyer, Thomas, Wirths, Oliver
Publicado 2023

Combined long-term enriched environment and caffeine supplementation improve memory function in C57Bl6 mice

por Stazi, Martina, Zampar, Silvia, Nadolny, Madeleine, Büschgens, Luca, Meyer, Thomas, Wirths, Oliver
Publicado 2022

Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

por Wirths, Oliver, Breyhan, Henning, Cynis, Holger, Schilling, Stephan, Demuth, Hans-Ulrich, Bayer, Thomas A.
Publicado 2009

Accumulation of intraneuronal Aβ correlates with ApoE4 genotype

por Christensen, Ditte Z., Schneider-Axmann, Thomas, Lucassen, Paul J., Bayer, Thomas A., Wirths, Oliver
Publicado 2010

Circulating immune complexes of Aβ and IgM in plasma of patients with Alzheimer’s disease

por Marcello, Andrea, Wirths, Oliver, Schneider-Axmann, Thomas, Degerman-Gunnarsson, Malin, Lannfelt, Lars, Bayer, Thomas A.
Publicado 2009

Matrix Development for the Detection of Phosphorylated Amyloid-β Peptides by MALDI-TOF-MS

por Liepold, Thomas, Klafki, Hans-Wolfgang, Kumar, Sathish, Walter, Jochen, Wirths, Oliver, Wiltfang, Jens, Jahn, Olaf
Publicado 2023

Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

por Hüttenrauch, Melanie, Ogorek, Isabella, Klafki, Hans, Otto, Markus, Stadelmann, Christine, Weggen, Sascha, Wiltfang, Jens, Wirths, Oliver
Publicado 2018