CDK8-Novel Therapeutic Opportunities

por Menzl, Ingeborg, Witalisz-Siepracka, Agnieszka, Sexl, Veronika
Publicado 2019

Untwining Anti-Tumor and Immunosuppressive Effects of JAK Inhibitors—A Strategy for Hematological Malignancies?

por Klein, Klara, Stoiber, Dagmar, Sexl, Veronika, Witalisz-Siepracka, Agnieszka
Publicado 2021

The Ups and Downs of STAT Inhibition in Acute Myeloid Leukemia

por Moser, Bernhard, Edtmayer, Sophie, Witalisz-Siepracka, Agnieszka, Stoiber, Dagmar
Publicado 2021

The Multifaceted Role of STAT3 in NK-Cell Tumor Surveillance

por Witalisz-Siepracka, Agnieszka, Klein, Klara, Zdársky, Bernhard, Stoiber, Dagmar
Publicado 2022

Loss of JAK1 Drives Innate Immune Deficiency

por Witalisz-Siepracka, Agnieszka, Klein, Klara, Prinz, Daniela, Leidenfrost, Nicoletta, Schabbauer, Gernot, Dohnal, Alexander, Sexl, Veronika
Publicado 2019

PB1805: BREAKING A PARADIGM: LOSS OF STAT3 INCREASES INVASION IN MLL-AF9-DRIVEN ACUTE MYELOID LEUKEMIA

por Zdársky, Bernhard, Edtmayer, Sophie, Boigenzahn, Stefanie, Witalisz-Siepracka, Agnieszka, Fiedler, Kerstin, Weiss, Stefanie, Stoiber-Sakaguchi, Dagmar
Publicado 2023

PB1783: UNRAVELING THE TUMOR SUPPRESSIVE ROLE OF STAT3B IN ACUTE MYELOID LEUKEMIA

por Edtmayer, Sophie, Witalisz-Siepracka, Agnieszka, Zdársky, Bernhard, Weiss, Stefanie, Fiedler, Kerstin, Eder, Thomas, Poli, Valeria, Grebien, Florian, Stoiber, Dagmar
Publicado 2023

T Cell-Intrinsic CDK6 Is Dispensable for Anti-Viral and Anti-Tumor Responses In Vivo

por Klein, Klara, Witalisz-Siepracka, Agnieszka, Gotthardt, Dagmar, Agerer, Benedikt, Locker, Felix, Grausenburger, Reinhard, Knab, Vanessa Maria, Bergthaler, Andreas, Sexl, Veronika
Publicado 2021

In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity

por Prchal-Murphy, Michaela, Witalisz-Siepracka, Agnieszka, Bednarik, Karoline T, Putz, Eva Maria, Gotthardt, Dagmar, Meissl, Katrin, Sexl, Veronika, Müller, Mathias, Strobl, Birgit
Publicado 2015

STAT5B(N642H) drives transformation of NKT cells: a novel mouse model for CD56(+) T-LGL leukemia

por Klein, Klara, Witalisz-Siepracka, Agnieszka, Maurer, Barbara, Prinz, Daniela, Heller, Gerwin, Leidenfrost, Nicoletta, Prchal-Murphy, Michaela, Suske, Tobias, Moriggl, Richard, Sexl, Veronika
Publicado 2019

Triple-negative breast cancer cells rely on kinase-independent functions of CDK8 to evade NK-cell-mediated tumor surveillance

por Knab, Vanessa Maria, Gotthardt, Dagmar, Klein, Klara, Grausenburger, Reinhard, Heller, Gerwin, Menzl, Ingeborg, Prinz, Daniela, Trifinopoulos, Jana, List, Julia, Fux, Daniela, Witalisz-Siepracka, Agnieszka, Sexl, Veronika
Publicado 2021

Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2

por Prinz, Daniela, Klein, Klara, List, Julia, Knab, Vanessa M., Menzl, Ingeborg, Leidenfrost, Nicoletta, Heller, Gerwin, Polić, Bojan, Putz, Eva Maria, Witalisz‐Siepracka, Agnieszka, Sexl, Veronika, Gotthardt, Dagmar
Publicado 2020

STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity

por Meissl, Katrin, Simonović, Natalija, Amenitsch, Lena, Witalisz-Siepracka, Agnieszka, Klein, Klara, Lassnig, Caroline, Puga, Ana, Vogl, Claus, Poelzl, Andrea, Bosmann, Markus, Dohnal, Alexander, Sexl, Veronika, Müller, Mathias, Strobl, Birgit
Publicado 2020