In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1

por Pak, Y. Anne, Long, Amanda J., Annes, William F., Witcher, Jennifer W., Knadler, Mary Pat, Ayan-Oshodi, Mosun A., Mitchell, Malcolm I., Leese, Phillip, Hillgren, Kathleen M.
Publicado 2017

Target modulation and pharmacokinetics/pharmacodynamics translation of the BTK inhibitor poseltinib for model-informed phase II dose selection

por Byun, Joo-Yun, Koh, Yi T., Jang, Sun Young, Witcher, Jennifer W., Chan, Jason R., Pustilnik, Anna, Daniels, Mark J., Kim, Young Hoon, Suh, Kwee Hyun, Linnik, Matthew D., Lee, Young-Mi
Publicado 2021

Determining Pharmacological Selectivity of the Kappa Opioid Receptor Antagonist LY2456302 Using Pupillometry as a Translational Biomarker in Rat and Human

por Rorick-Kehn, Linda M., Witcher, Jennifer W., Lowe, Stephen L., Gonzales, Celedon R., Weller, Mary Ann, Bell, Robert L., Hart, John C., Need, Anne B., McKinzie, Jamie H., Statnick, Michael A., Suico, Jeffrey G., McKinzie, David L., Tauscher-Wisniewski, Sitra, Mitch, Charles H., Stoltz, Randall R., Wong, Conrad J.
Publicado 2015